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Targeting AATF reprograms the tumor microenvironment and suppresses hepatocellular carcinoma via MIR100HG-TGF-β signaling.

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Title: Targeting AATF reprograms the tumor microenvironment and suppresses hepatocellular carcinoma via MIR100HG-TGF-β signaling.
Authors: Suresh D; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India., Srinivas AN; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India., Gunaseelan B; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India., Bharadwaj SAA; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India., Moorthy M; TheraCUES Innovations Pvt. Ltd, Bangalore 560092, India., Ramaswamy G; TheraCUES Innovations Pvt. Ltd, Bangalore 560092, India., Satish S; Department of Pathology, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India., Vishwanath P; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India., Santhekadur PK; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India., Chidambaram SB; Department of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India., Kumar DP; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India.
Source: Molecular therapy. Oncology [Mol Ther Oncol] 2026 Jun 06; Vol. 34 (3), pp. 201259. Date of Electronic Publication: 2026 Jun 06 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 9918752083706676 Publication Model: eCollection Cited Medium: Print ISSN: 2950-3299 (Print) Linking ISSN: 29503299 NLM ISO Abbreviation: Mol Ther Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2950-3299
DOI:10.1016/j.omton.2026.201259