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Targeting AATF reprograms the tumor microenvironment and suppresses hepatocellular carcinoma via MIR100HG-TGF-β signaling.

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Title: Targeting AATF reprograms the tumor microenvironment and suppresses hepatocellular carcinoma via MIR100HG-TGF-β signaling.
Authors: Suresh D; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India., Srinivas AN; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India., Gunaseelan B; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India., Bharadwaj SAA; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India., Moorthy M; TheraCUES Innovations Pvt. Ltd, Bangalore 560092, India., Ramaswamy G; TheraCUES Innovations Pvt. Ltd, Bangalore 560092, India., Satish S; Department of Pathology, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India., Vishwanath P; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India., Santhekadur PK; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India., Chidambaram SB; Department of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India., Kumar DP; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India.
Source: Molecular therapy. Oncology [Mol Ther Oncol] 2026 Jun 06; Vol. 34 (3), pp. 201259. Date of Electronic Publication: 2026 Jun 06 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 9918752083706676 Publication Model: eCollection Cited Medium: Print ISSN: 2950-3299 (Print) Linking ISSN: 29503299 NLM ISO Abbreviation: Mol Ther Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting AATF reprograms the tumor microenvironment and suppresses hepatocellular carcinoma via MIR100HG-TGF-β signaling.
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  Data: <searchLink fieldCode="AU" term="%22Suresh+D%22">Suresh D</searchLink>; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India.<br /><searchLink fieldCode="AU" term="%22Srinivas+AN%22">Srinivas AN</searchLink>; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India.<br /><searchLink fieldCode="AU" term="%22Gunaseelan+B%22">Gunaseelan B</searchLink>; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India.<br /><searchLink fieldCode="AU" term="%22Bharadwaj+SAA%22">Bharadwaj SAA</searchLink>; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India.<br /><searchLink fieldCode="AU" term="%22Moorthy+M%22">Moorthy M</searchLink>; TheraCUES Innovations Pvt. Ltd, Bangalore 560092, India.<br /><searchLink fieldCode="AU" term="%22Ramaswamy+G%22">Ramaswamy G</searchLink>; TheraCUES Innovations Pvt. Ltd, Bangalore 560092, India.<br /><searchLink fieldCode="AU" term="%22Satish+S%22">Satish S</searchLink>; Department of Pathology, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India.<br /><searchLink fieldCode="AU" term="%22Vishwanath+P%22">Vishwanath P</searchLink>; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India.<br /><searchLink fieldCode="AU" term="%22Santhekadur+PK%22">Santhekadur PK</searchLink>; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India.<br /><searchLink fieldCode="AU" term="%22Chidambaram+SB%22">Chidambaram SB</searchLink>; Department of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India.<br /><searchLink fieldCode="AU" term="%22Kumar+DP%22">Kumar DP</searchLink>; Department of Biochemistry, CEMR Lab, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India.
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  Data: <searchLink fieldCode="JN" term="%229918752083706676%22">Molecular therapy. Oncology</searchLink> [Mol Ther Oncol] 2026 Jun 06; Vol. 34 (3), pp. 201259. <i>Date of Electronic Publication: </i>2026 Jun 06 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Inc%22">Elsevier Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9918752083706676 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2950-3299 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2229503299%22">29503299 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther Oncol <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2026 Jun 06
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