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Avatrombopag Versus Placebo for Persistent Chemotherapy-Induced Thrombocytopenia in GI Cancers: The Phase II ACT-GI Trial.

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Title: Avatrombopag Versus Placebo for Persistent Chemotherapy-Induced Thrombocytopenia in GI Cancers: The Phase II ACT-GI Trial.
Authors: Al-Samkari H; Mass General Brigham Cancer Institute, Massachusetts General Hospital, Boston, MA.; Harvard Medical School, Boston, MA., Shatzel JJ; Knight Cancer Institute, Oregon Health and Science University, Portland, OR., Panch SR; Fred Hutch Cancer Center, University of Washington, Seattle, WA., Keating JH; Dana-Farber Cancer Institute, Boston, MA., Walsh EP; Mass General Brigham Cancer Institute, Massachusetts General Hospital, Boston, MA.; Harvard Medical School, Boston, MA., Weekes CD; Mass General Brigham Cancer Institute, Massachusetts General Hospital, Boston, MA.; Harvard Medical School, Boston, MA., Kardosh A; Knight Cancer Institute, Oregon Health and Science University, Portland, OR., Cohen SA; Fred Hutch Cancer Center, University of Washington, Seattle, WA., Cohen JJ; University of Miami Health System/Sylvester Comprehensive Cancer Center, Miami, FL., Hodges PG; Mass General Brigham Cancer Institute, Massachusetts General Hospital, Boston, MA., Dhaver SE; Mass General Brigham Cancer Institute, Massachusetts General Hospital, Boston, MA., Strojny N; Mass General Brigham Cancer Institute, Massachusetts General Hospital, Boston, MA., Donovan C; Mass General Brigham Cancer Institute, Massachusetts General Hospital, Boston, MA., Belibasakis C; Mass General Brigham Cancer Institute, Massachusetts General Hospital, Boston, MA., Soff GA; University of Miami Health System/Sylvester Comprehensive Cancer Center, Miami, FL.
Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2026 Jul 13, pp. JCO2600568. Date of Electronic Publication: 2026 Jul 13.
Publication Type: Journal Article
Journal Info: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Al-Samkari+H%22">Al-Samkari H</searchLink>; Mass General Brigham Cancer Institute, Massachusetts General Hospital, Boston, MA.; Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Shatzel+JJ%22">Shatzel JJ</searchLink>; Knight Cancer Institute, Oregon Health and Science University, Portland, OR.<br /><searchLink fieldCode="AU" term="%22Panch+SR%22">Panch SR</searchLink>; Fred Hutch Cancer Center, University of Washington, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Keating+JH%22">Keating JH</searchLink>; Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Walsh+EP%22">Walsh EP</searchLink>; Mass General Brigham Cancer Institute, Massachusetts General Hospital, Boston, MA.; Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Weekes+CD%22">Weekes CD</searchLink>; Mass General Brigham Cancer Institute, Massachusetts General Hospital, Boston, MA.; Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Kardosh+A%22">Kardosh A</searchLink>; Knight Cancer Institute, Oregon Health and Science University, Portland, OR.<br /><searchLink fieldCode="AU" term="%22Cohen+SA%22">Cohen SA</searchLink>; Fred Hutch Cancer Center, University of Washington, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Cohen+JJ%22">Cohen JJ</searchLink>; University of Miami Health System/Sylvester Comprehensive Cancer Center, Miami, FL.<br /><searchLink fieldCode="AU" term="%22Hodges+PG%22">Hodges PG</searchLink>; Mass General Brigham Cancer Institute, Massachusetts General Hospital, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Dhaver+SE%22">Dhaver SE</searchLink>; Mass General Brigham Cancer Institute, Massachusetts General Hospital, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Strojny+N%22">Strojny N</searchLink>; Mass General Brigham Cancer Institute, Massachusetts General Hospital, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Donovan+C%22">Donovan C</searchLink>; Mass General Brigham Cancer Institute, Massachusetts General Hospital, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Belibasakis+C%22">Belibasakis C</searchLink>; Mass General Brigham Cancer Institute, Massachusetts General Hospital, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Soff+GA%22">Soff GA</searchLink>; University of Miami Health System/Sylvester Comprehensive Cancer Center, Miami, FL.
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  Data: <searchLink fieldCode="JN" term="%228309333%22">Journal of clinical oncology : official journal of the American Society of Clinical Oncology</searchLink> [J Clin Oncol] 2026 Jul 13, pp. JCO2600568. <i>Date of Electronic Publication: </i>2026 Jul 13.
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