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The ARDS, Pneumonia, and Sepsis (APS) Consortium: Rationale, Design, and Feasibility of a National Platform for Phenotyping Critical Illness Syndromes.

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Title: The ARDS, Pneumonia, and Sepsis (APS) Consortium: Rationale, Design, and Feasibility of a National Platform for Phenotyping Critical Illness Syndromes.
Authors: Self WH; Vanderbilt Institute for Clinical and Translational Research and Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Calfee CS; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Departments of Medicine and Anesthesia, University of California, San Francisco, San Francisco, CA, USA., Brown SM; Department of Pulmonary and Critical Care Medicine, Intermountain Medical Center, Salt Lake City, UT, USA., Moss M; Division of Pulmonary, Allergy, and Critical Care Medicine, University of Colorado School of Medicine, Aurora, CO, USA., Ware LB; Departments of Medicine and Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN, USA., Hyzy RC; University of Michigan, Ann Arbor, MI, USA., Meyer NJ; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Reilly JP; Division of Pulmonary, Allergy, and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Harhay MO; Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Shashaty MGS; Division of Pulmonary, Allergy, and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Sandsmark DK; Department of Neurology, Division of Neurocritical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Auriemma CL; Division of Pulmonary, Allergy, and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Palliative and Advanced Illness Research (PAIR) Center, University of Pennsylvania, Philadelphia, PA, USA., Jones TK; University of Pennsylvania, Philadelphia, PA, USA., Prescott HC; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Dickson RP; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine; Department of Microbiology and Immunology; Weil Institute for Critical Care Research & Innovation, University of Michigan, Ann Arbor, MI, USA., Nelson K; University of Michigan, Ann Arbor, MI, USA., McSparron JI; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA., Lagina M; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA., Denstaedt SJ; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA., Admon AJ; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School; Veterans Affairs Center for Clinical Management Research; Ann Arbor, MI, USA., Patel BK; Section of Pulmonary and Critical Care, Department of Medicine, University of Chicago, Chicago, IL, USA., Wolfe KS; University of Chicago, Chicago, IL, USA., Hite RD; University of Cincinnati College of Medicine, Cincinnati, OH, USA., Hudock KM; Division of Pulmonary, Sleep & Critical Care Medicine, Department of Medicine, University of Cincinnati, Cincinnati, OH, USA., Bastarache JA; Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Koyama T; Vanderbilt University Medical Center, Nashville, TN, USA., Kerchberger VE; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA., Ely EW; Vanderbilt University Medical Center, Nashville, TN, USA; Tennessee Valley Veteran's Affairs Geriatric Research Education Clinical Center (GRECC), Nashville, TN, USA., Jackson JC; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Sinha P; Department of Anesthesiology, Washington University in Saint Louis School of Medicine, Saint Louis, MO, USA., Mudd PA; Department of Emergency Medicine, Washington University in Saint Louis School of Medicine, Saint Louis, MO, USA., Kraft BD; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA., Fremont RD; Meharry Medical College, Nashville, TN, USA., Singh R; Meharry Medical College, Nashville, TN, USA., Aggarwal NR; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Colorado Anschutz, Aurora, CO, USA., Jolley SE; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Colorado Anschutz, Aurora, CO, USA., Burnham EL; University of Colorado School of Medicine, Aurora, CO, USA., Mantelli RA; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Colorado Anschutz, Aurora, CO, USA., Janssen WJ; Division of Pulmonary, Critical Care, and Sleep Medicine, National Jewish Health, Denver, CO, USA., Moore CM; Center for Genes, Environment and Health, National Jewish Health, Denver, CO, USA., Douglas IS; Westchester Medical Center Health, New York Medical College, Valhalla, NY, USA., Peterson R; University of Iowa, Iowa City, IA, USA., Peltan ID; Department of Pulmonary and Critical Care Medicine, Intermountain Medical Center, Salt Lake City, UT, USA., Barkauskas CE; Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, Duke University, Durham, NC, USA., Pratt EH; Duke University School of Medicine, Durham, NC, USA., Harris ES; University of Utah, Salt Lake City, UT, USA., Scharfstein DO; Division of Biostatistics, Department of Population Health Sciences, University of Utah School of Medicine, Salt Lake City, UT, USA., Needham DM; Division of Pulmonary and Critical Care Medicine and Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Sahetya SK; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA., Parker AM; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Outcomes After Surgery and Critical Illness Research Group, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Iwashyna TJ; Johns Hopkins University, Baltimore, MD, USA., Shenderov K; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Matthay MA; Departments of Medicine and Anesthesia, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA., Alipanah-Lechner N; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Magee L; University of California, San Franscico, San Francisco, CA, USA., Shwartzman T; University of California, San Franscico, San Francisco, CA, USA., Lin C; University of California, San Franscico, San Francisco, CA, USA., Weingart MF; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Langelier CR; Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Chao O; University of California, San Franscico, San Francisco, CA, USA., Hendrickson CM; Zuckerberg San Francisco General Hospital, University of California, San Franscico, San Francisco, CA, USA., Kornblith LZ; Zuckerberg San Francisco General Hospital, University of California, San Franscico, San Francisco, CA, USA., Chak S; Zuckerberg San Francisco General Hospital, University of California, San Franscico, San Francisco, CA, USA., Bardillon K; Zuckerberg San Francisco General Hospital, San Francisco, CA, USA., Rodriguez KH; University of California, San Franscico, San Francisco, CA, USA., Rogers AJ; Division of Pulmonary, Allergy, and Critical Care Medicine, Stanford University, Stanford, CA, USA., Moore AR; Division of Pulmonary, Allergy, and Critical Care Medicine, Stanford University, Stanford, CA, USA., Levitt JE; Division of Pulmonary, Allergy, and Critical Care Medicine, Stanford University, Palo Alto, CA, USA., Vojnik R; Stanford University, Stanford, CA, USA., Perez C; Stanford University, Palo Alto, CA, USA., Lindsell CJ; Duke University, Durham, NC, USA., Shotwell MS; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Blette BS; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Imhoff BW; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Rice TW; Vanderbilt University Medical Center, Nashville, TN, USA., Rhoads JP; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA., Womack KN; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA., Merkel AR; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA., Ahmad LN; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA., Zhao X; National Institute of General Medical Sciences, National Institutes of Health, Bethesda, MD, USA., Grandon IE; Division of Lung Diseases, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Gong MN; Division of Critical Care Medicine, Division of Pulmonary Medicine, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Corporate Authors: ARDS, Pneumonia, and Sepsis (APS) Consortium
Source: Chest [Chest] 2026 Jul 13. Date of Electronic Publication: 2026 Jul 13.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0231335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1931-3543 (Electronic) Linking ISSN: 00123692 NLM ISO Abbreviation: Chest Subsets: MEDLINE
Database: MEDLINE Ultimate
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      – PersonEntity:
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            NameFull: Shenderov K
      – PersonEntity:
          Name:
            NameFull: Matthay MA
      – PersonEntity:
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            NameFull: Alipanah-Lechner N
      – PersonEntity:
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            NameFull: Shwartzman T
      – PersonEntity:
          Name:
            NameFull: Lin C
      – PersonEntity:
          Name:
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      – PersonEntity:
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      – PersonEntity:
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            NameFull: Rice TW
      – PersonEntity:
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      – PersonEntity:
          Name:
            NameFull: Ahmad LN
      – PersonEntity:
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            NameFull: Zhao X
      – PersonEntity:
          Name:
            NameFull: Grandon IE
      – PersonEntity:
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            NameFull: Gong MN
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 13
              M: 07
              Text: 2026 Jul 13
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1931-3543
          Titles:
            – TitleFull: Chest
              Type: main
ResultId 1