Widespread white matter microstructural abnormalities in treatment‑naïve patients with first‑episode schizophrenia revealed by fixel-based analysis.
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| Title: | Widespread white matter microstructural abnormalities in treatment‑naïve patients with first‑episode schizophrenia revealed by fixel-based analysis. |
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| Authors: | Yang M; Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.; Nanhu Brain-computer Interface Institute, Hangzhou, Zhejiang, China.; Zhejiang Key Laboratory of Clinical and Basic Research for Psychiatric Diseases, Hangzhou, Zhejiang, China., Li H; Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.; Nanhu Brain-computer Interface Institute, Hangzhou, Zhejiang, China.; Zhejiang Key Laboratory of Clinical and Basic Research for Psychiatric Diseases, Hangzhou, Zhejiang, China., Li M; Mental Health Center of West China Hospital, Sichuan University, Chengdu, Sichuan, China., Wang Q; Mental Health Center of West China Hospital, Sichuan University, Chengdu, Sichuan, China., Deng L; Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.; Nanhu Brain-computer Interface Institute, Hangzhou, Zhejiang, China.; Zhejiang Key Laboratory of Clinical and Basic Research for Psychiatric Diseases, Hangzhou, Zhejiang, China., Zhao L; Mental Health Center of West China Hospital, Sichuan University, Chengdu, Sichuan, China., Yu H; Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.; Nanhu Brain-computer Interface Institute, Hangzhou, Zhejiang, China.; Zhejiang Key Laboratory of Clinical and Basic Research for Psychiatric Diseases, Hangzhou, Zhejiang, China., Li X; Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.; Nanhu Brain-computer Interface Institute, Hangzhou, Zhejiang, China.; Zhejiang Key Laboratory of Clinical and Basic Research for Psychiatric Diseases, Hangzhou, Zhejiang, China., Deng W; Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.; Nanhu Brain-computer Interface Institute, Hangzhou, Zhejiang, China.; Zhejiang Key Laboratory of Clinical and Basic Research for Psychiatric Diseases, Hangzhou, Zhejiang, China.; NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University, Hangzhou, Zhejiang, China.; Liangzhu Laboratory, MOE Frontier Science Center for Brain Science and Brain-machine Integration, State Key Laboratory of Brain-machine Intelligence, Zhejiang University, Hangzhou, Zhejiang, China., Guo W; Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.; Nanhu Brain-computer Interface Institute, Hangzhou, Zhejiang, China.; Zhejiang Key Laboratory of Clinical and Basic Research for Psychiatric Diseases, Hangzhou, Zhejiang, China., Wei W; Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. weiweih7@zju.edu.cn.; Nanhu Brain-computer Interface Institute, Hangzhou, Zhejiang, China. weiweih7@zju.edu.cn.; Zhejiang Key Laboratory of Clinical and Basic Research for Psychiatric Diseases, Hangzhou, Zhejiang, China. weiweih7@zju.edu.cn.; NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University, Hangzhou, Zhejiang, China. weiweih7@zju.edu.cn.; Liangzhu Laboratory, MOE Frontier Science Center for Brain Science and Brain-machine Integration, State Key Laboratory of Brain-machine Intelligence, Zhejiang University, Hangzhou, Zhejiang, China. weiweih7@zju.edu.cn., Li T; Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. litaozjusc@zju.edu.cn.; Nanhu Brain-computer Interface Institute, Hangzhou, Zhejiang, China. litaozjusc@zju.edu.cn.; Zhejiang Key Laboratory of Clinical and Basic Research for Psychiatric Diseases, Hangzhou, Zhejiang, China. litaozjusc@zju.edu.cn.; NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University, Hangzhou, Zhejiang, China. litaozjusc@zju.edu.cn.; Liangzhu Laboratory, MOE Frontier Science Center for Brain Science and Brain-machine Integration, State Key Laboratory of Brain-machine Intelligence, Zhejiang University, Hangzhou, Zhejiang, China. litaozjusc@zju.edu.cn. |
| Source: | Translational psychiatry [Transl Psychiatry] 2026 Jul 13; Vol. 16 (1). Date of Electronic Publication: 2026 Jul 13. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2158-3188 |
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| DOI: | 10.1038/s41398-026-04277-y |
