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A tumor profiling resource for ovarian cancer: insights into chemotherapy-driven heterogeneity and personalized treatment strategy.

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Title: A tumor profiling resource for ovarian cancer: insights into chemotherapy-driven heterogeneity and personalized treatment strategy.
Authors: Jacob F; Ovarian Cancer Research, Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland. francis.jacob@unibas.ch., Wegmann R; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland., Ficek-Pascual J; Department of Computer Science, ETH Zurich, Zurich, Switzerland., Lischetti U; Ovarian Cancer Research, Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland., Kuipers J; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Chevrier S; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.; Navignostics AG, Horgen, Switzerland., Prummer M; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.; NEXUS Personalized Health Technologies, ETH Zurich, Zurich, Switzerland., Toussaint NC; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.; NEXUS Personalized Health Technologies, ETH Zurich, Zurich, Switzerland.; Swiss Data Science Center, ETH Zürich, Zurich, Switzerland., Alborelli I; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland., Coelho R; Ovarian Cancer Research, Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland., Casanova R; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland., Goetze S; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Department of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland.; Swiss Multi-Omics Center, PHRT-CPAC, ETH Zurich, Zurich, Switzerland., Gut G; Department of Molecular Life Sciences, University of Zurich, Zurich, Switzerland., Baciu-Drăgan MA; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Bertolini A; NEXUS Personalized Health Technologies, ETH Zurich, Zurich, Switzerland., Bonilla X; Department of Computer Science, ETH Zurich, Zurich, Switzerland., Brugger J; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland., Brune MM; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland., Calgua B; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland., Engler S; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland., Esposito C; Department of Molecular Life Sciences, University of Zurich, Zurich, Switzerland., Ferreira PF; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Jacobs A; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.; Navignostics AG, Horgen, Switzerland., Lombardo FC; Ovarian Cancer Research, Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland., Malsot P; Department of Computer Science, ETH Zurich, Zurich, Switzerland.; AI Center, ETH Zurich, Zurich, Switzerland., Mena J; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland., Miglino N; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland., Milani ES; Department of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland., Sarabia Del Castillo J; Department of Molecular Life Sciences, University of Zurich, Zurich, Switzerland., Sivapatham S; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland., Sobottka-Brillout BA; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Faculty of Medicine, Zurich, Switzerland., Tanna T; Department of Computer Science, ETH Zurich, Zurich, Switzerland.; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Zwimpfer TA; Ovarian Cancer Research, Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland., Aebersold R; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland., Bacac M; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Zurich, Zurich, Switzerland., Beerenwinkel N; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland., Beisel C; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Bodenmiller B; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.; Department of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland., Koelzer VH; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Faculty of Medicine, Zurich, Switzerland., Lehmann KV; Department of Computer Science, ETH Zurich, Zurich, Switzerland., Levesque MP; Department of Dermatology, University of Zurich Hospital, Zurich, Switzerland., Moch H; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Faculty of Medicine, Zurich, Switzerland., Muenst S; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland., Pelkmans L; Department of Molecular Life Sciences, University of Zurich, Zurich, Switzerland., Manz MG; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland., Rätsch G; Department of Computer Science, ETH Zurich, Zurich, Switzerland.; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.; AI Center, ETH Zurich, Zurich, Switzerland., Singer F; NEXUS Personalized Health Technologies, ETH Zurich, Zurich, Switzerland., Snijder B; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland.; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland., Theocharides APA; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland., Tolnay M; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland., Wicki A; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Faculty of Medicine, Zurich, Switzerland., Wollscheid B; Department of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland., Heinzelmann-Schwarz V; Ovarian Cancer Research, Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland. viola.heinzelmann@usb.ch.; Department of Gynecology and Gynecologic Oncology, University Hospital Basel, Basel, Switzerland. viola.heinzelmann@usb.ch.
Corporate Authors: TumorProfiler Consortium
Source: Nature communications [Nat Commun] 2026 Jul 13. Date of Electronic Publication: 2026 Jul 13.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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