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HumanFilt: a multi-reference host depletion pipeline improves Fusobacterium detection accuracy in tumor WGS data sets.

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Title: HumanFilt: a multi-reference host depletion pipeline improves Fusobacterium detection accuracy in tumor WGS data sets.
Authors: Frolova M; Department of Physiology and Medical Physics and RCSI Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland., Maguire B; Department of Physiology and Medical Physics and RCSI Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Department of Colorectal Surgery, Beaumont Hospital, Dublin, Ireland., Duessmann H; Department of Physiology and Medical Physics and RCSI Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland., Rayan M; Department of Physiology and Medical Physics and RCSI Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Department of Pharmaceutical Sciences, College of Pharmacy, QU Health, Qatar University, Doha, Qatar., Burke C; UCD School of Medicine, UCD Conway Institute, University College Dublin, Dublin, Ireland., Korashy HM; Department of Pharmaceutical Sciences, College of Pharmacy, QU Health, Qatar University, Doha, Qatar., Raman A; UCD School of Medicine, UCD Conway Institute, University College Dublin, Dublin, Ireland., Gallagher WM; UCD School of Medicine, UCD Conway Institute, University College Dublin, Dublin, Ireland., Burke JP; Department of Colorectal Surgery, Beaumont Hospital, Dublin, Ireland., Furney SJ; Department of Physiology and Medical Physics and RCSI Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland., Prehn JHM; Department of Physiology and Medical Physics and RCSI Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
Source: MSystems [mSystems] 2026 Jul 14, pp. e0055026. Date of Electronic Publication: 2026 Jul 14.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101680636 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2379-5077 (Electronic) Linking ISSN: 23795077 NLM ISO Abbreviation: mSystems Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Frolova+M%22">Frolova M</searchLink>; Department of Physiology and Medical Physics and RCSI Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Maguire+B%22">Maguire B</searchLink>; Department of Physiology and Medical Physics and RCSI Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Department of Colorectal Surgery, Beaumont Hospital, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Duessmann+H%22">Duessmann H</searchLink>; Department of Physiology and Medical Physics and RCSI Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Rayan+M%22">Rayan M</searchLink>; Department of Physiology and Medical Physics and RCSI Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Department of Pharmaceutical Sciences, College of Pharmacy, QU Health, Qatar University, Doha, Qatar.<br /><searchLink fieldCode="AU" term="%22Burke+C%22">Burke C</searchLink>; UCD School of Medicine, UCD Conway Institute, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Korashy+HM%22">Korashy HM</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy, QU Health, Qatar University, Doha, Qatar.<br /><searchLink fieldCode="AU" term="%22Raman+A%22">Raman A</searchLink>; UCD School of Medicine, UCD Conway Institute, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Gallagher+WM%22">Gallagher WM</searchLink>; UCD School of Medicine, UCD Conway Institute, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Burke+JP%22">Burke JP</searchLink>; Department of Colorectal Surgery, Beaumont Hospital, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Furney+SJ%22">Furney SJ</searchLink>; Department of Physiology and Medical Physics and RCSI Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Prehn+JHM%22">Prehn JHM</searchLink>; Department of Physiology and Medical Physics and RCSI Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
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  Data: <searchLink fieldCode="JN" term="%22101680636%22">MSystems</searchLink> [mSystems] 2026 Jul 14, pp. e0055026. <i>Date of Electronic Publication: </i>2026 Jul 14.
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              Text: 2026 Jul 14
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