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Pyridine-containing antitumor agents: structure-oriented medicinal chemistry, structure-activity relationships, and ADMET liabilities.

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Title: Pyridine-containing antitumor agents: structure-oriented medicinal chemistry, structure-activity relationships, and ADMET liabilities.
Authors: Zhao W; School of Medicine, Xi'an Peihua University, Xi'an, 710125, China. 004157@peihua.edu.cn., Bie B; School of Medicine, Xi'an Peihua University, Xi'an, 710125, China., Wang J; School of Medicine, Xi'an Peihua University, Xi'an, 710125, China., Liu X; School of Medicine, Xi'an Peihua University, Xi'an, 710125, China., Fang H; School of Medicine, Xi'an Peihua University, Xi'an, 710125, China., Niu R; School of Medicine, Xi'an Peihua University, Xi'an, 710125, China.
Source: Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents [Med Chem Res] 2026 Jul; Vol. 35 (7), pp. 1316-1329. Date of Electronic Publication: 2026 Jun 27.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 9211347 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8120 (Electronic) Linking ISSN: 10542523 NLM ISO Abbreviation: Med Chem Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Pyridine-containing antitumor agents: structure-oriented medicinal chemistry, structure-activity relationships, and ADMET liabilities.
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  Data: <searchLink fieldCode="AU" term="%22Zhao+W%22">Zhao W</searchLink>; School of Medicine, Xi'an Peihua University, Xi'an, 710125, China. 004157@peihua.edu.cn.<br /><searchLink fieldCode="AU" term="%22Bie+B%22">Bie B</searchLink>; School of Medicine, Xi'an Peihua University, Xi'an, 710125, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; School of Medicine, Xi'an Peihua University, Xi'an, 710125, China.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; School of Medicine, Xi'an Peihua University, Xi'an, 710125, China.<br /><searchLink fieldCode="AU" term="%22Fang+H%22">Fang H</searchLink>; School of Medicine, Xi'an Peihua University, Xi'an, 710125, China.<br /><searchLink fieldCode="AU" term="%22Niu+R%22">Niu R</searchLink>; School of Medicine, Xi'an Peihua University, Xi'an, 710125, China.
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  Data: <searchLink fieldCode="JN" term="%229211347%22">Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents</searchLink> [Med Chem Res] 2026 Jul; Vol. 35 (7), pp. 1316-1329. <i>Date of Electronic Publication: </i>2026 Jun 27.
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      – Type: doi
        Value: 10.1007/s00044-026-03588-5
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      – Code: eng
        Text: English
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        StartPage: 1316
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      – TitleFull: Pyridine-containing antitumor agents: structure-oriented medicinal chemistry, structure-activity relationships, and ADMET liabilities.
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            NameFull: Zhao W
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            NameFull: Bie B
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            NameFull: Fang H
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            – D: 01
              M: 07
              Text: 2026 Jul
              Type: published
              Y: 2026
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              Value: 35
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              Value: 7
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            – TitleFull: Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents
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