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Normal spermatogenesis in older men is associated with compensatory transcriptome changes.

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Title: Normal spermatogenesis in older men is associated with compensatory transcriptome changes.
Authors: Wang Y; Institute of Reproductive Genetics, Centre of Medical Genetics, University of Münster, Münster, Germany.; Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany., Berres S; Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany.; Medical Bioinformatics, Medical Faculty, Ruhr University, Bochum, Germany., Krenz H; Institute of Medical Informatics, University of Münster, Münster, Germany., Tekath T; Institute of Medical Informatics, University of Münster, Münster, Germany., Wöste M; Institute of Medical Informatics, University of Münster, Münster, Germany., Sandmann S; Institute of Medical Data Science, Otto-Von-Guericke University, Magdeburg, Germany., Körtje A; Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany., Henrich A; Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany.; Max Planck Institute for Biology of Ageing, Cologne, Germany., Terwort N; Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany., Tüttelmann F; Institute of Reproductive Genetics, Centre of Medical Genetics, University of Münster, Münster, Germany., Neuhaus N; Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany., Kliesch S; Department of Andrology, Centre of Reproductive Medicine and Andrology, University Hospital Münster, Münster, Germany., Wistuba J; Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany., Gromoll J; Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany., Laurentino S; Institute of Reproductive Genetics, Centre of Medical Genetics, University of Münster, Münster, Germany. Sandra.Laurentino@ukmuenster.de.; Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany. Sandra.Laurentino@ukmuenster.de.
Source: GeroScience [Geroscience] 2026 Jul 14. Date of Electronic Publication: 2026 Jul 14.
Publication Type: Journal Article
Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE
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  Data: Normal spermatogenesis in older men is associated with compensatory transcriptome changes.
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  Data: <searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Institute of Reproductive Genetics, Centre of Medical Genetics, University of Münster, Münster, Germany.; Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Berres+S%22">Berres S</searchLink>; Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany.; Medical Bioinformatics, Medical Faculty, Ruhr University, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Krenz+H%22">Krenz H</searchLink>; Institute of Medical Informatics, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Tekath+T%22">Tekath T</searchLink>; Institute of Medical Informatics, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Wöste+M%22">Wöste M</searchLink>; Institute of Medical Informatics, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Sandmann+S%22">Sandmann S</searchLink>; Institute of Medical Data Science, Otto-Von-Guericke University, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Körtje+A%22">Körtje A</searchLink>; Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Henrich+A%22">Henrich A</searchLink>; Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany.; Max Planck Institute for Biology of Ageing, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Terwort+N%22">Terwort N</searchLink>; Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Tüttelmann+F%22">Tüttelmann F</searchLink>; Institute of Reproductive Genetics, Centre of Medical Genetics, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Neuhaus+N%22">Neuhaus N</searchLink>; Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Kliesch+S%22">Kliesch S</searchLink>; Department of Andrology, Centre of Reproductive Medicine and Andrology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Wistuba+J%22">Wistuba J</searchLink>; Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Gromoll+J%22">Gromoll J</searchLink>; Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Laurentino+S%22">Laurentino S</searchLink>; Institute of Reproductive Genetics, Centre of Medical Genetics, University of Münster, Münster, Germany. Sandra.Laurentino@ukmuenster.de.; Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany. Sandra.Laurentino@ukmuenster.de.
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              Text: 2026 Jul 14
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