CXCR4-EGFR heteromers show ligand-dependent changes in conformation and signaling.
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| Title: | CXCR4-EGFR heteromers show ligand-dependent changes in conformation and signaling. |
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| Authors: | Comez D; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands Nottingham, Nottingham, UK., Anbuhl SM; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, VU University, Amsterdam, the Netherlands; QVQ, Universiteitsweg 101, 3584 CG Utrecht, the Netherlands., Platt S; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands Nottingham, Nottingham, UK., Isaac OC; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands Nottingham, Nottingham, UK., Karsai N; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands Nottingham, Nottingham, UK., Markus R; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands Nottingham, Nottingham, UK., Siderius M; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, VU University, Amsterdam, the Netherlands., Smit MJ; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, VU University, Amsterdam, the Netherlands., Heukers R; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, VU University, Amsterdam, the Netherlands; QVQ, Universiteitsweg 101, 3584 CG Utrecht, the Netherlands., Kilpatrick LE; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands Nottingham, Nottingham, UK; Division of Bimolecular Science and Medicinal Chemistry, Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham, UK., Hill SJ; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands Nottingham, Nottingham, UK. Electronic address: steve.hill@nottingham.ac.uk. |
| Source: | Cell chemical biology [Cell Chem Biol] 2026 Jul 14. Date of Electronic Publication: 2026 Jul 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42447861 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: CXCR4-EGFR heteromers show ligand-dependent changes in conformation and signaling. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Comez+D%22">Comez D</searchLink>; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Anbuhl+SM%22">Anbuhl SM</searchLink>; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, VU University, Amsterdam, the Netherlands; QVQ, Universiteitsweg 101, 3584 CG Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Platt+S%22">Platt S</searchLink>; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Isaac+OC%22">Isaac OC</searchLink>; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Karsai+N%22">Karsai N</searchLink>; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Markus+R%22">Markus R</searchLink>; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Siderius+M%22">Siderius M</searchLink>; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, VU University, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Smit+MJ%22">Smit MJ</searchLink>; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, VU University, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Heukers+R%22">Heukers R</searchLink>; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, VU University, Amsterdam, the Netherlands; QVQ, Universiteitsweg 101, 3584 CG Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Kilpatrick+LE%22">Kilpatrick LE</searchLink>; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands Nottingham, Nottingham, UK; Division of Bimolecular Science and Medicinal Chemistry, Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Hill+SJ%22">Hill SJ</searchLink>; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands Nottingham, Nottingham, UK. Electronic address: steve.hill@nottingham.ac.uk. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101676030%22">Cell chemical biology</searchLink> [Cell Chem Biol] 2026 Jul 14. <i>Date of Electronic Publication: </i>2026 Jul 14. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101676030 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2451-9448 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224519448%22">24519448 </searchLink><i>NLM ISO Abbreviation: </i>Cell Chem Biol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42447861 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.chembiol.2026.06.008 Languages: – Code: eng Text: English Titles: – TitleFull: CXCR4-EGFR heteromers show ligand-dependent changes in conformation and signaling. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Comez D – PersonEntity: Name: NameFull: Anbuhl SM – PersonEntity: Name: NameFull: Platt S – PersonEntity: Name: NameFull: Isaac OC – PersonEntity: Name: NameFull: Karsai N – PersonEntity: Name: NameFull: Markus R – PersonEntity: Name: NameFull: Siderius M – PersonEntity: Name: NameFull: Smit MJ – PersonEntity: Name: NameFull: Heukers R – PersonEntity: Name: NameFull: Kilpatrick LE – PersonEntity: Name: NameFull: Hill SJ IsPartOfRelationships: – BibEntity: Dates: – D: 14 M: 07 Text: 2026 Jul 14 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2451-9448 Titles: – TitleFull: Cell chemical biology Type: main |
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