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Targeted antibody-drug conjugates for rhabdomyosarcoma and other FGFR4-expressing cancers.

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Title: Targeted antibody-drug conjugates for rhabdomyosarcoma and other FGFR4-expressing cancers.
Authors: Tian M; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Jia K; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Wu JT; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Cheuk AT; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Fang S; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, Binghamton, NY, USA., Ojo VT; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, Binghamton, NY, USA., Pope EG; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Milewski D; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Kim YY; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Chou HC; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Kelekar A; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Dey S; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Yu Y; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Rahman MA; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, Binghamton, NY, USA., Khan RMN; Clinical Pharmacology Lab, Clinical Center, National Institutes of Health Clinical Center, Bethesda, MD, USA., Arisa O; Clinical Pharmacology Lab, Clinical Center, National Institutes of Health Clinical Center, Bethesda, MD, USA., Figg WD; Clinical Pharmacology Lab, Clinical Center, National Institutes of Health Clinical Center, Bethesda, MD, USA; Clinical Pharmacology Program, Center for Cancer Research, National Institutes of Health Clinical Center, Bethesda, MD, USA., Sharan SK; Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, NIH, Frederick, MD 21702, USA; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA., Ohler ZW; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA., Szabova L; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA., Difilippantonio S; Laboratory Animal Sciences Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA., Shor B; Manhattan BioSolutions, Inc., New York, NY, USA., Tumey LN; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, Binghamton, NY, USA., Wei JS; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: weij@mail.nih.gov., Khan J; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: khanjav@mail.nih.gov.
Source: Cell reports. Medicine [Cell Rep Med] 2026 Jul 14, pp. 102922. Date of Electronic Publication: 2026 Jul 14.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE
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  Data: Targeted antibody-drug conjugates for rhabdomyosarcoma and other FGFR4-expressing cancers.
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  Data: <searchLink fieldCode="AU" term="%22Tian+M%22">Tian M</searchLink>; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Jia+K%22">Jia K</searchLink>; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Wu+JT%22">Wu JT</searchLink>; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Cheuk+AT%22">Cheuk AT</searchLink>; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Fang+S%22">Fang S</searchLink>; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, Binghamton, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ojo+VT%22">Ojo VT</searchLink>; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, Binghamton, NY, USA.<br /><searchLink fieldCode="AU" term="%22Pope+EG%22">Pope EG</searchLink>; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Milewski+D%22">Milewski D</searchLink>; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kim+YY%22">Kim YY</searchLink>; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Chou+HC%22">Chou HC</searchLink>; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kelekar+A%22">Kelekar A</searchLink>; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Dey+S%22">Dey S</searchLink>; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Yu+Y%22">Yu Y</searchLink>; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Rahman+MA%22">Rahman MA</searchLink>; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, Binghamton, NY, USA.<br /><searchLink fieldCode="AU" term="%22Khan+RMN%22">Khan RMN</searchLink>; Clinical Pharmacology Lab, Clinical Center, National Institutes of Health Clinical Center, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Arisa+O%22">Arisa O</searchLink>; Clinical Pharmacology Lab, Clinical Center, National Institutes of Health Clinical Center, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Figg+WD%22">Figg WD</searchLink>; Clinical Pharmacology Lab, Clinical Center, National Institutes of Health Clinical Center, Bethesda, MD, USA; Clinical Pharmacology Program, Center for Cancer Research, National Institutes of Health Clinical Center, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Sharan+SK%22">Sharan SK</searchLink>; Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, NIH, Frederick, MD 21702, USA; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.<br /><searchLink fieldCode="AU" term="%22Ohler+ZW%22">Ohler ZW</searchLink>; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.<br /><searchLink fieldCode="AU" term="%22Szabova+L%22">Szabova L</searchLink>; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.<br /><searchLink fieldCode="AU" term="%22Difilippantonio+S%22">Difilippantonio S</searchLink>; Laboratory Animal Sciences Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.<br /><searchLink fieldCode="AU" term="%22Shor+B%22">Shor B</searchLink>; Manhattan BioSolutions, Inc., New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Tumey+LN%22">Tumey LN</searchLink>; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, Binghamton, NY, USA.<br /><searchLink fieldCode="AU" term="%22Wei+JS%22">Wei JS</searchLink>; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: weij@mail.nih.gov.<br /><searchLink fieldCode="AU" term="%22Khan+J%22">Khan J</searchLink>; Oncogenomics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: khanjav@mail.nih.gov.
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  Data: <searchLink fieldCode="JN" term="%22101766894%22">Cell reports. Medicine</searchLink> [Cell Rep Med] 2026 Jul 14, pp. 102922. <i>Date of Electronic Publication: </i>2026 Jul 14.
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