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DANGER/ITPRIP-mediated iron homeostasis mediates ferroptosis resistance and presents a potential therapeutic target in ccRCC.

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Title: DANGER/ITPRIP-mediated iron homeostasis mediates ferroptosis resistance and presents a potential therapeutic target in ccRCC.
Authors: Fan K; School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, 266071, China., Zhou Y; School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, 266071, China., Xu J; Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, China; Peking University Cancer Hospital & Institute, Beijing, 100142, China., Mathis BJ; Department of Cardiovascular Surgery, Institute of Medicine, University of Tsukuba, Tsukuba, 305-8575, Japan., Hao J; School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, 266071, China., Feng Y; Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, China., Lin J; Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, China., Yu X; School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, 266071, China., Liu S; School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, 266071, China., Sun D; Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, China. Electronic address: d.qsun@163.com., Wu W; School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, 266071, China. Electronic address: weiwei.wu@qdu.edu.cn.
Source: Free radical biology & medicine [Free Radic Biol Med] 2026 Jul 14; Vol. 255, pp. 16-34. Date of Electronic Publication: 2026 Jul 14.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: DANGER/ITPRIP-mediated iron homeostasis mediates ferroptosis resistance and presents a potential therapeutic target in ccRCC.
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  Data: <searchLink fieldCode="AU" term="%22Fan+K%22">Fan K</searchLink>; School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, 266071, China.<br /><searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, 266071, China.<br /><searchLink fieldCode="AU" term="%22Xu+J%22">Xu J</searchLink>; Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, China; Peking University Cancer Hospital & Institute, Beijing, 100142, China.<br /><searchLink fieldCode="AU" term="%22Mathis+BJ%22">Mathis BJ</searchLink>; Department of Cardiovascular Surgery, Institute of Medicine, University of Tsukuba, Tsukuba, 305-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Hao+J%22">Hao J</searchLink>; School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, 266071, China.<br /><searchLink fieldCode="AU" term="%22Feng+Y%22">Feng Y</searchLink>; Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, China.<br /><searchLink fieldCode="AU" term="%22Lin+J%22">Lin J</searchLink>; Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, China.<br /><searchLink fieldCode="AU" term="%22Yu+X%22">Yu X</searchLink>; School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, 266071, China.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, 266071, China.<br /><searchLink fieldCode="AU" term="%22Sun+D%22">Sun D</searchLink>; Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, China. Electronic address: d.qsun@163.com.<br /><searchLink fieldCode="AU" term="%22Wu+W%22">Wu W</searchLink>; School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, 266071, China. Electronic address: weiwei.wu@qdu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%228709159%22">Free radical biology & medicine</searchLink> [Free Radic Biol Med] 2026 Jul 14; Vol. 255, pp. 16-34. <i>Date of Electronic Publication: </i>2026 Jul 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8709159 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-4596 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208915849%22">08915849 </searchLink><i>NLM ISO Abbreviation: </i>Free Radic Biol Med <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.freeradbiomed.2026.07.022
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              Text: 2026 Jul 14
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