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Reactivation of DRP1 plays a functional role in resistance to MEK inhibition in pancreatic cancer cells.

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Title: Reactivation of DRP1 plays a functional role in resistance to MEK inhibition in pancreatic cancer cells.
Authors: Sharmin S; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia Health System, Charlottesville, VA, USA., Kashatus JA; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia Health System, Charlottesville, VA, USA., Adair SJ; Department of Surgery, University of Virginia Health System, Charlottesville, VA, USA., Loewgren EB; Department of Biomedical Engineering, University of Virginia Health System, Charlottesville, VA, USA., Fallahi-Sichani M; Department of Biomedical Engineering, University of Virginia Health System, Charlottesville, VA, USA., Bauer TW; Department of Surgery, University of Virginia Health System, Charlottesville, VA, USA., Kashatus DF; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia Health System, Charlottesville, VA, USA. kashatus@virginia.edu.; Department of Biomedical Engineering, University of Virginia Health System, Charlottesville, VA, USA. kashatus@virginia.edu.
Source: British journal of cancer [Br J Cancer] 2026 Jul 14. Date of Electronic Publication: 2026 Jul 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Sharmin+S%22">Sharmin S</searchLink>; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia Health System, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Kashatus+JA%22">Kashatus JA</searchLink>; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia Health System, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Adair+SJ%22">Adair SJ</searchLink>; Department of Surgery, University of Virginia Health System, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Loewgren+EB%22">Loewgren EB</searchLink>; Department of Biomedical Engineering, University of Virginia Health System, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Fallahi-Sichani+M%22">Fallahi-Sichani M</searchLink>; Department of Biomedical Engineering, University of Virginia Health System, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Bauer+TW%22">Bauer TW</searchLink>; Department of Surgery, University of Virginia Health System, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Kashatus+DF%22">Kashatus DF</searchLink>; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia Health System, Charlottesville, VA, USA. kashatus@virginia.edu.; Department of Biomedical Engineering, University of Virginia Health System, Charlottesville, VA, USA. kashatus@virginia.edu.
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  Data: <searchLink fieldCode="JN" term="%220370635%22">British journal of cancer</searchLink> [Br J Cancer] 2026 Jul 14. <i>Date of Electronic Publication: </i>2026 Jul 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+on+behalf+of+Cancer+Research+UK%22">Nature Publishing Group on behalf of Cancer Research UK </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0370635 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-1827 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200070920%22">00070920 </searchLink><i>NLM ISO Abbreviation: </i>Br J Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41416-026-03542-7
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              Text: 2026 Jul 14
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