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Neuromodulatory effects of berberine chloride against aluminum chloride/D-Galactose induced Alzheimer-like neurodegeneration model in rats.

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Title: Neuromodulatory effects of berberine chloride against aluminum chloride/D-Galactose induced Alzheimer-like neurodegeneration model in rats.
Authors: Adefisan-Adeoye AO; Chemical Sciences Department, Faculty of Computing and Applied Sciences, Dominion University Ibadan, Ibadan, Nigeria. adedoyinadefisan22@gmail.com.; Department of Pediatric, Hematology-Oncology Section, Baylor College of Medicine, Houston, TX, USA. adedoyinadefisan22@gmail.com., Oluwadamilare H; Chemical Sciences Department, Faculty of Computing and Applied Sciences, Dominion University Ibadan, Ibadan, Nigeria., Aisedion M; Molecular Drug Metabolism and Toxicology Laboratories, Department of Biochemistry, College of Medicine, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Nigeria., Shittu TS; Department of Physiology, College of Medicine, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Nigeria., Amangele T; Department of Physiology, College of Medicine, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Nigeria., Adeoye TD; Federal Teaching Hospital, Ido-Ekiti, Ekiti, Nigeria., Unuofin JO; Department of Life and Consumer Sciences, College of Agriculture and Environmental Sciences, University of South Africa, Pretoria, South Africa., Orimolade BM; Geriatric Medicine, Caithness General Hospital, NHS Highland, Wick, UK., Lebelo SL; Department of Life and Consumer Sciences, College of Agriculture and Environmental Sciences, University of South Africa, Pretoria, South Africa. Lebelol@unisa.ac.za., Adaramoye OA; Molecular Drug Metabolism and Toxicology Laboratories, Department of Biochemistry, College of Medicine, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Nigeria.
Source: Scientific reports [Sci Rep] 2026 Jul 14. Date of Electronic Publication: 2026 Jul 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: Neuromodulatory effects of berberine chloride against aluminum chloride/D-Galactose induced Alzheimer-like neurodegeneration model in rats.
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  Data: <searchLink fieldCode="AU" term="%22Adefisan-Adeoye+AO%22">Adefisan-Adeoye AO</searchLink>; Chemical Sciences Department, Faculty of Computing and Applied Sciences, Dominion University Ibadan, Ibadan, Nigeria. adedoyinadefisan22@gmail.com.; Department of Pediatric, Hematology-Oncology Section, Baylor College of Medicine, Houston, TX, USA. adedoyinadefisan22@gmail.com.<br /><searchLink fieldCode="AU" term="%22Oluwadamilare+H%22">Oluwadamilare H</searchLink>; Chemical Sciences Department, Faculty of Computing and Applied Sciences, Dominion University Ibadan, Ibadan, Nigeria.<br /><searchLink fieldCode="AU" term="%22Aisedion+M%22">Aisedion M</searchLink>; Molecular Drug Metabolism and Toxicology Laboratories, Department of Biochemistry, College of Medicine, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Nigeria.<br /><searchLink fieldCode="AU" term="%22Shittu+TS%22">Shittu TS</searchLink>; Department of Physiology, College of Medicine, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Nigeria.<br /><searchLink fieldCode="AU" term="%22Amangele+T%22">Amangele T</searchLink>; Department of Physiology, College of Medicine, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Nigeria.<br /><searchLink fieldCode="AU" term="%22Adeoye+TD%22">Adeoye TD</searchLink>; Federal Teaching Hospital, Ido-Ekiti, Ekiti, Nigeria.<br /><searchLink fieldCode="AU" term="%22Unuofin+JO%22">Unuofin JO</searchLink>; Department of Life and Consumer Sciences, College of Agriculture and Environmental Sciences, University of South Africa, Pretoria, South Africa.<br /><searchLink fieldCode="AU" term="%22Orimolade+BM%22">Orimolade BM</searchLink>; Geriatric Medicine, Caithness General Hospital, NHS Highland, Wick, UK.<br /><searchLink fieldCode="AU" term="%22Lebelo+SL%22">Lebelo SL</searchLink>; Department of Life and Consumer Sciences, College of Agriculture and Environmental Sciences, University of South Africa, Pretoria, South Africa. Lebelol@unisa.ac.za.<br /><searchLink fieldCode="AU" term="%22Adaramoye+OA%22">Adaramoye OA</searchLink>; Molecular Drug Metabolism and Toxicology Laboratories, Department of Biochemistry, College of Medicine, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Nigeria.
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        Value: 10.1038/s41598-026-61600-9
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              Text: 2026 Jul 14
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