Adjuvant therapy with total salvianolic acid injection enhances the safety and efficacy of recombinant prourokinase in ischemic stroke by mitigating blood-brain barrier disruption.
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| Title: | Adjuvant therapy with total salvianolic acid injection enhances the safety and efficacy of recombinant prourokinase in ischemic stroke by mitigating blood-brain barrier disruption. |
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| Authors: | Wang XY; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, 38 Xueyuan Road, Beijing, 100191, People's Republic of China.; China Rehabilitation Science Institute, China Rehabilitation Research Center, Beijing, China., Li Q; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Beijing, China., Yan L; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Beijing, China., Wang D; Beijing Luhe Hospital Affiliated to Capital Medical University, Beijing, China., Pan CS; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Beijing, China., Fan JY; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Beijing, China., Ma ZZ; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, 38 Xueyuan Road, Beijing, 100191, People's Republic of China. zhma@bjmu.edu.cn.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China. zhma@bjmu.edu.cn.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China. zhma@bjmu.edu.cn.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Beijing, China. zhma@bjmu.edu.cn., Han JY; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, 38 Xueyuan Road, Beijing, 100191, People's Republic of China. hanjingyan@bjmu.edu.cn.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China. hanjingyan@bjmu.edu.cn.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China. hanjingyan@bjmu.edu.cn.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China. hanjingyan@bjmu.edu.cn.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Beijing, China. hanjingyan@bjmu.edu.cn. |
| Source: | Journal of translational medicine [J Transl Med] 2026 Jul 14. Date of Electronic Publication: 2026 Jul 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42449381 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Adjuvant therapy with total salvianolic acid injection enhances the safety and efficacy of recombinant prourokinase in ischemic stroke by mitigating blood-brain barrier disruption. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Wang+XY%22">Wang XY</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, 38 Xueyuan Road, Beijing, 100191, People's Republic of China.; China Rehabilitation Science Institute, China Rehabilitation Research Center, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Yan+L%22">Yan L</searchLink>; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+D%22">Wang D</searchLink>; Beijing Luhe Hospital Affiliated to Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Pan+CS%22">Pan CS</searchLink>; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Fan+JY%22">Fan JY</searchLink>; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Ma+ZZ%22">Ma ZZ</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, 38 Xueyuan Road, Beijing, 100191, People's Republic of China. zhma@bjmu.edu.cn.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China. zhma@bjmu.edu.cn.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China. zhma@bjmu.edu.cn.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Beijing, China. zhma@bjmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Han+JY%22">Han JY</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, 38 Xueyuan Road, Beijing, 100191, People's Republic of China. hanjingyan@bjmu.edu.cn.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China. hanjingyan@bjmu.edu.cn.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China. hanjingyan@bjmu.edu.cn.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China. hanjingyan@bjmu.edu.cn.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Beijing, China. hanjingyan@bjmu.edu.cn. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101190741%22">Journal of translational medicine</searchLink> [J Transl Med] 2026 Jul 14. <i>Date of Electronic Publication: </i>2026 Jul 14. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101190741 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1479-5876 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214795876%22">14795876 </searchLink><i>NLM ISO Abbreviation: </i>J Transl Med <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42449381 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s12967-026-08583-3 Languages: – Code: eng Text: English Titles: – TitleFull: Adjuvant therapy with total salvianolic acid injection enhances the safety and efficacy of recombinant prourokinase in ischemic stroke by mitigating blood-brain barrier disruption. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wang XY – PersonEntity: Name: NameFull: Li Q – PersonEntity: Name: NameFull: Yan L – PersonEntity: Name: NameFull: Wang D – PersonEntity: Name: NameFull: Pan CS – PersonEntity: Name: NameFull: Fan JY – PersonEntity: Name: NameFull: Ma ZZ – PersonEntity: Name: NameFull: Han JY IsPartOfRelationships: – BibEntity: Dates: – D: 14 M: 07 Text: 2026 Jul 14 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1479-5876 Titles: – TitleFull: Journal of translational medicine Type: main |
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