Three-order interactions in the alpha band of default mode network EEGs based on O-information rate: insights from aging and Alzheimer's disease.

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Title: Three-order interactions in the alpha band of default mode network EEGs based on O-information rate: insights from aging and Alzheimer's disease.
Authors: Azami H; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 1025 Queen St W, Toronto, ON, M6J 1H1, Canada.; Adult Neurodevelopment and Geriatric Psychiatry Division, Centre for Addiction and Mental Health, 1025 Queen St W, Toronto, ON, M6J 1H1, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, 250 College Street, Toronto, ON, M5T 1R8, Canada., Antonacci Y; Department of Engineering, University of Palermo, Viale Delle Scienze, Palermo, 90128, Italy., Blumberger DM; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 1025 Queen St W, Toronto, ON, M6J 1H1, Canada.; Adult Neurodevelopment and Geriatric Psychiatry Division, Centre for Addiction and Mental Health, 1025 Queen St W, Toronto, ON, M6J 1H1, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, 250 College Street, Toronto, ON, M5T 1R8, Canada.; Temerty Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, 1025 Queen St W, Toronto, ON, M6J 1H1, Canada., Brooks H; Adult Neurodevelopment and Geriatric Psychiatry Division, Centre for Addiction and Mental Health, 1025 Queen St W, Toronto, ON, M6J 1H1, Canada., Faes L; Department of Engineering, University of Palermo, Viale Delle Scienze, Palermo, 90128, Italy.; Faculty of Technical Sciences, University of Novi Sad, Novi Sad City, 21000, Republic of Serbia., Fischer CE; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, 30 Bond St Toronto, Toronto, ON, M5B 1W8, Canada., Flint A; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, 250 College Street, Toronto, ON, M5T 1R8, Canada.; University Health Network, 190 Elizabeth St, Toronto, ON, M5G 2C4, Canada., Herrmann N; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, 250 College Street, Toronto, ON, M5T 1R8, Canada.; Sunnybrook Health Sciences Centre, 2075 Bayview Ave, Toronto, ON, M4N 3M5, Canada., Kumar S; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 1025 Queen St W, Toronto, ON, M6J 1H1, Canada.; Adult Neurodevelopment and Geriatric Psychiatry Division, Centre for Addiction and Mental Health, 1025 Queen St W, Toronto, ON, M6J 1H1, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, 250 College Street, Toronto, ON, M5T 1R8, Canada., Gallagher D; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, 250 College Street, Toronto, ON, M5T 1R8, Canada.; Sunnybrook Health Sciences Centre, 2075 Bayview Ave, Toronto, ON, M4N 3M5, Canada., Mah L; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, 250 College Street, Toronto, ON, M5T 1R8, Canada.; Rotman Research Institute, Baycrest Health Sciences, 3560 Bathurst Street, North York, ON, M6A 2E1, Canada., Mulsant BH; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 1025 Queen St W, Toronto, ON, M6J 1H1, Canada.; Adult Neurodevelopment and Geriatric Psychiatry Division, Centre for Addiction and Mental Health, 1025 Queen St W, Toronto, ON, M6J 1H1, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, 250 College Street, Toronto, ON, M5T 1R8, Canada.; The Royal Ottawa Hospital, 1053 Carling Ave, Ottawa, ON, K1Y 4E9, Canada., Schoer N; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 1025 Queen St W, Toronto, ON, M6J 1H1, Canada., Pollock BG; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 1025 Queen St W, Toronto, ON, M6J 1H1, Canada.; Adult Neurodevelopment and Geriatric Psychiatry Division, Centre for Addiction and Mental Health, 1025 Queen St W, Toronto, ON, M6J 1H1, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, 250 College Street, Toronto, ON, M5T 1R8, Canada., Rajji TK; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 1025 Queen St W, Toronto, ON, M6J 1H1, Canada. tarek.rajji@utsouthwestern.edu.; Adult Neurodevelopment and Geriatric Psychiatry Division, Centre for Addiction and Mental Health, 1025 Queen St W, Toronto, ON, M6J 1H1, Canada. tarek.rajji@utsouthwestern.edu.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, 250 College Street, Toronto, ON, M5T 1R8, Canada. tarek.rajji@utsouthwestern.edu.; Temerty Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, 1025 Queen St W, Toronto, ON, M6J 1H1, Canada. tarek.rajji@utsouthwestern.edu.; University of Texas Southwestern Medical Center, 2201 Inwood Road, Suite NC6.102, Dallas, TX, 75235-9070, USA. tarek.rajji@utsouthwestern.edu.
Corporate Authors: PACt-M. D. Study Group
Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2026 Jul 15. Date of Electronic Publication: 2026 Jul 15.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1758-9193
DOI:10.1186/s13195-026-02131-3