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Suppression of Post-Ischemic Cardiac Remodelling and Inflammatory Response by a Novel Sphingolipid Modifier, CIN038.

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Title: Suppression of Post-Ischemic Cardiac Remodelling and Inflammatory Response by a Novel Sphingolipid Modifier, CIN038.
Authors: Wang BH; Heart Failure Research Group, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.; Monash Alfred Baker Centre for Cardiovascular Research, School of Translational Medicine, Monash University, Melbourne 3004, Australia.; Biomarker Discovery, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.; Centre for Cardiovascular Research in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia., Savira F; Biomarker Discovery, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.; Centre for Cardiovascular Research in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.; School of Health and Social Development, Faculty of Health, Deakin University, Melbourne 3125, Australia., Xiong X; Biomarker Discovery, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.; Centre for Cardiovascular Research in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia., Donner DD; Translational Cardiology Centre, Baker Heart and Diabetes Institute, Melbourne 3004, Australia., Kiriazis H; Translational Cardiology Centre, Baker Heart and Diabetes Institute, Melbourne 3004, Australia., Brown A; Translational Cardiology Centre, Baker Heart and Diabetes Institute, Melbourne 3004, Australia., Huang L; Monash Alfred Baker Centre for Cardiovascular Research, School of Translational Medicine, Monash University, Melbourne 3004, Australia.; Biomarker Discovery, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.; Centre for Cardiovascular Research in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia., Mellet N; Metabolomics Research Group, Baker Heart and Diabetes Institute, Melbourne 3004, Australia., Huynh K; Metabolomics Research Group, Baker Heart and Diabetes Institute, Melbourne 3004, Australia., Meikle PJ; Metabolomics Research Group, Baker Heart and Diabetes Institute, Melbourne 3004, Australia., Creek D; Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne 3052, Australia., Reid C; Centre for Cardiovascular Research in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.; School of Public Health, Curtin University, Perth 6102, Australia., Flynn BL; Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne 3052, Australia., Kaye DM; Heart Failure Research Group, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.; Monash Alfred Baker Centre for Cardiovascular Research, School of Translational Medicine, Monash University, Melbourne 3004, Australia., Liew D; Centre for Cardiovascular Research in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.; Faculty of Medicine, University of Adelaide, Adelaide 5000, Australia., Magaye RR; Heart Failure Research Group, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.; Monash Alfred Baker Centre for Cardiovascular Research, School of Translational Medicine, Monash University, Melbourne 3004, Australia.; Biomarker Discovery, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.; Centre for Cardiovascular Research in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.
Source: International journal of molecular sciences [Int J Mol Sci] 2026 Jun 26; Vol. 27 (13). Date of Electronic Publication: 2026 Jun 26.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Wang+BH%22">Wang BH</searchLink>; Heart Failure Research Group, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.; Monash Alfred Baker Centre for Cardiovascular Research, School of Translational Medicine, Monash University, Melbourne 3004, Australia.; Biomarker Discovery, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.; Centre for Cardiovascular Research in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.<br /><searchLink fieldCode="AU" term="%22Savira+F%22">Savira F</searchLink>; Biomarker Discovery, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.; Centre for Cardiovascular Research in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.; School of Health and Social Development, Faculty of Health, Deakin University, Melbourne 3125, Australia.<br /><searchLink fieldCode="AU" term="%22Xiong+X%22">Xiong X</searchLink>; Biomarker Discovery, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.; Centre for Cardiovascular Research in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.<br /><searchLink fieldCode="AU" term="%22Donner+DD%22">Donner DD</searchLink>; Translational Cardiology Centre, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.<br /><searchLink fieldCode="AU" term="%22Kiriazis+H%22">Kiriazis H</searchLink>; Translational Cardiology Centre, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.<br /><searchLink fieldCode="AU" term="%22Brown+A%22">Brown A</searchLink>; Translational Cardiology Centre, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.<br /><searchLink fieldCode="AU" term="%22Huang+L%22">Huang L</searchLink>; Monash Alfred Baker Centre for Cardiovascular Research, School of Translational Medicine, Monash University, Melbourne 3004, Australia.; Biomarker Discovery, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.; Centre for Cardiovascular Research in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.<br /><searchLink fieldCode="AU" term="%22Mellet+N%22">Mellet N</searchLink>; Metabolomics Research Group, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.<br /><searchLink fieldCode="AU" term="%22Huynh+K%22">Huynh K</searchLink>; Metabolomics Research Group, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.<br /><searchLink fieldCode="AU" term="%22Meikle+PJ%22">Meikle PJ</searchLink>; Metabolomics Research Group, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.<br /><searchLink fieldCode="AU" term="%22Creek+D%22">Creek D</searchLink>; Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Reid+C%22">Reid C</searchLink>; Centre for Cardiovascular Research in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.; School of Public Health, Curtin University, Perth 6102, Australia.<br /><searchLink fieldCode="AU" term="%22Flynn+BL%22">Flynn BL</searchLink>; Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Kaye+DM%22">Kaye DM</searchLink>; Heart Failure Research Group, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.; Monash Alfred Baker Centre for Cardiovascular Research, School of Translational Medicine, Monash University, Melbourne 3004, Australia.<br /><searchLink fieldCode="AU" term="%22Liew+D%22">Liew D</searchLink>; Centre for Cardiovascular Research in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.; Faculty of Medicine, University of Adelaide, Adelaide 5000, Australia.<br /><searchLink fieldCode="AU" term="%22Magaye+RR%22">Magaye RR</searchLink>; Heart Failure Research Group, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.; Monash Alfred Baker Centre for Cardiovascular Research, School of Translational Medicine, Monash University, Melbourne 3004, Australia.; Biomarker Discovery, Baker Heart and Diabetes Institute, Melbourne 3004, Australia.; Centre for Cardiovascular Research in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.
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        Value: 10.3390/ijms27135776
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        Text: English
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      – TitleFull: Suppression of Post-Ischemic Cardiac Remodelling and Inflammatory Response by a Novel Sphingolipid Modifier, CIN038.
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