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Effects of Botanical Variation, Plant Part, and Extraction Technique on Mitragynine and 7-Hydroxymitragynine in Kratom (Mitragyna speciosa) Extracts Quantified by a Validated HPLC-DAD Method.

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Title: Effects of Botanical Variation, Plant Part, and Extraction Technique on Mitragynine and 7-Hydroxymitragynine in Kratom (Mitragyna speciosa) Extracts Quantified by a Validated HPLC-DAD Method.
Authors: Krongrawa W; Natural Products Research Center (NPRC), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.; Pharmaceutical Intellectual Center 'Prachote Plengwittaya', Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand., Ponphaiboon J; Natural Products Research Center (NPRC), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.; Division of Industrial Pharmacy, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand., Koedruen J; Natural Products Research Center (NPRC), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.; Division of Industrial Pharmacy, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand., Samran C; Siriraj Academic Center of Geriatric Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Samut Sakhon 74000, Thailand., Limmatvapirat S; Natural Products Research Center (NPRC), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.; Division of Industrial Pharmacy, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand., Limmatvapirat C; Natural Products Research Center (NPRC), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.; Division of Industrial Pharmacy, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.
Source: Molecules (Basel, Switzerland) [Molecules] 2026 Jun 25; Vol. 31 (13). Date of Electronic Publication: 2026 Jun 25.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effects of Botanical Variation, Plant Part, and Extraction Technique on Mitragynine and 7-Hydroxymitragynine in Kratom (Mitragyna speciosa) Extracts Quantified by a Validated HPLC-DAD Method.
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  Data: <searchLink fieldCode="AU" term="%22Krongrawa+W%22">Krongrawa W</searchLink>; Natural Products Research Center (NPRC), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.; Pharmaceutical Intellectual Center 'Prachote Plengwittaya', Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.<br /><searchLink fieldCode="AU" term="%22Ponphaiboon+J%22">Ponphaiboon J</searchLink>; Natural Products Research Center (NPRC), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.; Division of Industrial Pharmacy, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.<br /><searchLink fieldCode="AU" term="%22Koedruen+J%22">Koedruen J</searchLink>; Natural Products Research Center (NPRC), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.; Division of Industrial Pharmacy, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.<br /><searchLink fieldCode="AU" term="%22Samran+C%22">Samran C</searchLink>; Siriraj Academic Center of Geriatric Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Samut Sakhon 74000, Thailand.<br /><searchLink fieldCode="AU" term="%22Limmatvapirat+S%22">Limmatvapirat S</searchLink>; Natural Products Research Center (NPRC), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.; Division of Industrial Pharmacy, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.<br /><searchLink fieldCode="AU" term="%22Limmatvapirat+C%22">Limmatvapirat C</searchLink>; Natural Products Research Center (NPRC), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.; Division of Industrial Pharmacy, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.
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  Data: <searchLink fieldCode="JN" term="%22100964009%22">Molecules (Basel, Switzerland)</searchLink> [Molecules] 2026 Jun 25; Vol. 31 (13). <i>Date of Electronic Publication: </i>2026 Jun 25.
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      – TitleFull: Effects of Botanical Variation, Plant Part, and Extraction Technique on Mitragynine and 7-Hydroxymitragynine in Kratom (Mitragyna speciosa) Extracts Quantified by a Validated HPLC-DAD Method.
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