Glycolysis-mediated H3K18la modifications drive aggressive bladder cancer through metabolic and epigenetic reprogramming.

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Title: Glycolysis-mediated H3K18la modifications drive aggressive bladder cancer through metabolic and epigenetic reprogramming.
Authors: Wang Z; Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Department of Urology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China., Zhou Z; Department of Urology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.; National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China., Yang S; Department of Pediatric Urology, Guangzhou Medical University Affiliated Women and Children's Medical Center, Guangzhou, Guangdong, China., Zhao Z; Department of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China., Li X; The First Clinical College of Zhengzhou University, Zhengzhou University, Zhengzhou, China., Liu X; Department of Obstetrics and Gynecology, Xinyang Central Hospital, Xinyang, Henan, China., Cheng G; Department of Urology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.; National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China., Xu R; Department of Urology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.; National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China., Li Q; Department of Pediatric Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Xing D; Department of Emergency Intensive Care Unit (ICU), The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 30; Vol. 17, pp. 1777092. Date of Electronic Publication: 2026 Jun 30 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1777092