Glycolysis-mediated H3K18la modifications drive aggressive bladder cancer through metabolic and epigenetic reprogramming.

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Title: Glycolysis-mediated H3K18la modifications drive aggressive bladder cancer through metabolic and epigenetic reprogramming.
Authors: Wang Z; Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Department of Urology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China., Zhou Z; Department of Urology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.; National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China., Yang S; Department of Pediatric Urology, Guangzhou Medical University Affiliated Women and Children's Medical Center, Guangzhou, Guangdong, China., Zhao Z; Department of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China., Li X; The First Clinical College of Zhengzhou University, Zhengzhou University, Zhengzhou, China., Liu X; Department of Obstetrics and Gynecology, Xinyang Central Hospital, Xinyang, Henan, China., Cheng G; Department of Urology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.; National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China., Xu R; Department of Urology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.; National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China., Li Q; Department of Pediatric Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Xing D; Department of Emergency Intensive Care Unit (ICU), The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 30; Vol. 17, pp. 1777092. Date of Electronic Publication: 2026 Jun 30 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: Glycolysis-mediated H3K18la modifications drive aggressive bladder cancer through metabolic and epigenetic reprogramming.
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  Data: <searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Department of Urology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhou+Z%22">Zhou Z</searchLink>; Department of Urology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.; National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.<br /><searchLink fieldCode="AU" term="%22Yang+S%22">Yang S</searchLink>; Department of Pediatric Urology, Guangzhou Medical University Affiliated Women and Children's Medical Center, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Zhao+Z%22">Zhao Z</searchLink>; Department of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; The First Clinical College of Zhengzhou University, Zhengzhou University, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Department of Obstetrics and Gynecology, Xinyang Central Hospital, Xinyang, Henan, China.<br /><searchLink fieldCode="AU" term="%22Cheng+G%22">Cheng G</searchLink>; Department of Urology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.; National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.<br /><searchLink fieldCode="AU" term="%22Xu+R%22">Xu R</searchLink>; Department of Urology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.; National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.<br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; Department of Pediatric Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Xing+D%22">Xing D</searchLink>; Department of Emergency Intensive Care Unit (ICU), The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jun 30; Vol. 17, pp. 1777092. <i>Date of Electronic Publication: </i>2026 Jun 30 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun 30
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