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Tumor-intrinsic immune-genetic dynamics identify RNASE1 as an immune-evasion-associated biomarker and predictor of checkpoint blockade response in gastric adenocarcinoma.

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Title: Tumor-intrinsic immune-genetic dynamics identify RNASE1 as an immune-evasion-associated biomarker and predictor of checkpoint blockade response in gastric adenocarcinoma.
Authors: Xia H; Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, China., Guo T; Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, China., Zhang N; College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China., Lin D; Fuzhou University Affiliated Provincial Hospital, School of Medicine, Fuzhou University, Fuzhou, China., Guo G; Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, China., Tian Y; Fujian Medical University Union Hospital, Fuzhou, China., Huang C; Fuzhou University Affiliated Provincial Hospital, School of Medicine, Fuzhou University, Fuzhou, China., Guan S; Department of Colorectal Surgery, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China., Xue F; Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, China., Chen L; Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, China.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 30; Vol. 17, pp. 1884482. Date of Electronic Publication: 2026 Jun 30 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Tumor-intrinsic immune-genetic dynamics identify RNASE1 as an immune-evasion-associated biomarker and predictor of checkpoint blockade response in gastric adenocarcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Xia+H%22">Xia H</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Guo+T%22">Guo T</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+N%22">Zhang N</searchLink>; College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Lin+D%22">Lin D</searchLink>; Fuzhou University Affiliated Provincial Hospital, School of Medicine, Fuzhou University, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Guo+G%22">Guo G</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Tian+Y%22">Tian Y</searchLink>; Fujian Medical University Union Hospital, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Huang+C%22">Huang C</searchLink>; Fuzhou University Affiliated Provincial Hospital, School of Medicine, Fuzhou University, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Guan+S%22">Guan S</searchLink>; Department of Colorectal Surgery, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Xue+F%22">Xue F</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, China.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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        Value: 10.3389/fimmu.2026.1884482
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      – TitleFull: Tumor-intrinsic immune-genetic dynamics identify RNASE1 as an immune-evasion-associated biomarker and predictor of checkpoint blockade response in gastric adenocarcinoma.
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              Text: 2026 Jun 30
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