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Effects of CDDO‑TFEA on non‑small cell lung cancer growth, apoptosis, and stemness via the MEK/ERK pathway.

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Title: Effects of CDDO‑TFEA on non‑small cell lung cancer growth, apoptosis, and stemness via the MEK/ERK pathway.
Authors: Lee JY; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung City, Taiwan.; Division of Thoracic Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City, Taiwan., Chung CL; Division of Neurosurgery, Department of Surgery, Kaohsiung Municipal Siaogang Hospital, Kaohsiung, Taiwan.; Department of Surgery, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan., Tseng TT; Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No. 100, Shiquan 1St Rd., Sanmin Dist., 807378, Kaohsiung, Taiwan., Kuo SH; Department of Radiation Oncology, Kaohsiung Medical University Hospital Kaohsiung Medical University, Kaohsiung, Taiwan., Liu YP; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung City, Taiwan.; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan., Wu MT; College of Medicine, PhD Program in Environmental and Occupational Medicine, Kaohsiung Medical University, Kaohsiung City, Taiwan.; Department of Family Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City, Taiwan., Tsai HP; Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No. 100, Shiquan 1St Rd., Sanmin Dist., 807378, Kaohsiung, Taiwan. carbugino@gmail.com.; Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan. carbugino@gmail.com.; Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan. carbugino@gmail.com., Kwan AL; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung City, Taiwan. a_lkwan@yahoo.com.; Department of Surgery, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. a_lkwan@yahoo.com.; Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No. 100, Shiquan 1St Rd., Sanmin Dist., 807378, Kaohsiung, Taiwan. a_lkwan@yahoo.com.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. a_lkwan@yahoo.com.
Source: Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2026 Jul 15. Date of Electronic Publication: 2026 Jul 15.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7902060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1335 (Electronic) Linking ISSN: 01715216 NLM ISO Abbreviation: J Cancer Res Clin Oncol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Lee+JY%22">Lee JY</searchLink>; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung City, Taiwan.; Division of Thoracic Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chung+CL%22">Chung CL</searchLink>; Division of Neurosurgery, Department of Surgery, Kaohsiung Municipal Siaogang Hospital, Kaohsiung, Taiwan.; Department of Surgery, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tseng+TT%22">Tseng TT</searchLink>; Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No. 100, Shiquan 1St Rd., Sanmin Dist., 807378, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+SH%22">Kuo SH</searchLink>; Department of Radiation Oncology, Kaohsiung Medical University Hospital Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+YP%22">Liu YP</searchLink>; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung City, Taiwan.; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+MT%22">Wu MT</searchLink>; College of Medicine, PhD Program in Environmental and Occupational Medicine, Kaohsiung Medical University, Kaohsiung City, Taiwan.; Department of Family Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+HP%22">Tsai HP</searchLink>; Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No. 100, Shiquan 1St Rd., Sanmin Dist., 807378, Kaohsiung, Taiwan. carbugino@gmail.com.; Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan. carbugino@gmail.com.; Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan. carbugino@gmail.com.<br /><searchLink fieldCode="AU" term="%22Kwan+AL%22">Kwan AL</searchLink>; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung City, Taiwan. a_lkwan@yahoo.com.; Department of Surgery, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. a_lkwan@yahoo.com.; Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No. 100, Shiquan 1St Rd., Sanmin Dist., 807378, Kaohsiung, Taiwan. a_lkwan@yahoo.com.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. a_lkwan@yahoo.com.
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  Data: <searchLink fieldCode="JN" term="%227902060%22">Journal of cancer research and clinical oncology</searchLink> [J Cancer Res Clin Oncol] 2026 Jul 15. <i>Date of Electronic Publication: </i>2026 Jul 15.
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              Text: 2026 Jul 15
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