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DLBCL-microenvironment interactions: cytokine profiling and ECM-mediated ibrutinib resistance in a 3D bone-based model.

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Title: DLBCL-microenvironment interactions: cytokine profiling and ECM-mediated ibrutinib resistance in a 3D bone-based model.
Authors: Ceccato J; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy.; Laboratory of Myeloma and Lymphoma Pathobiology, Veneto Institute of Molecular Medicine (VIMM), Padua, Italy., Piazza M; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy., Gualtiero G; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy.; Laboratory of Myeloma and Lymphoma Pathobiology, Veneto Institute of Molecular Medicine (VIMM), Padua, Italy., Carraro S; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy., Cinetto F; Internal Medicine and Allergology and Clinical Immunology Unit, Treviso Ca' Foncello Hospital, Treviso, Italy., Biz C; Orthopedics and Orthopedic Oncology, Department of Surgery, Oncology and Gastroenterology (DiSCOG), University-Hospital of Padua, Padua, Italy., Manni S; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy.; Laboratory of Myeloma and Lymphoma Pathobiology, Veneto Institute of Molecular Medicine (VIMM), Padua, Italy., Pizzi M; Pathology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy., Pianalto S; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy., Zoletto S; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy., Carabotta V; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy., Danesin N; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy., Ruggieri P; Orthopedics and Orthopedic Oncology, Department of Surgery, Oncology and Gastroenterology (DiSCOG), University-Hospital of Padua, Padua, Italy., Dei Tos AP; Pathology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy., Piazza F; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy.; Laboratory of Myeloma and Lymphoma Pathobiology, Veneto Institute of Molecular Medicine (VIMM), Padua, Italy., Trentin L; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy., Vianello F; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy. fabrizio.vianello@unipd.it.
Source: Medical oncology (Northwood, London, England) [Med Oncol] 2026 Jul 15; Vol. 43 (9). Date of Electronic Publication: 2026 Jul 15.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 9435512 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-131X (Electronic) Linking ISSN: 13570560 NLM ISO Abbreviation: Med Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: DLBCL-microenvironment interactions: cytokine profiling and ECM-mediated ibrutinib resistance in a 3D bone-based model.
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  Data: <searchLink fieldCode="AU" term="%22Ceccato+J%22">Ceccato J</searchLink>; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy.; Laboratory of Myeloma and Lymphoma Pathobiology, Veneto Institute of Molecular Medicine (VIMM), Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Piazza+M%22">Piazza M</searchLink>; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Gualtiero+G%22">Gualtiero G</searchLink>; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy.; Laboratory of Myeloma and Lymphoma Pathobiology, Veneto Institute of Molecular Medicine (VIMM), Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Carraro+S%22">Carraro S</searchLink>; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Cinetto+F%22">Cinetto F</searchLink>; Internal Medicine and Allergology and Clinical Immunology Unit, Treviso Ca' Foncello Hospital, Treviso, Italy.<br /><searchLink fieldCode="AU" term="%22Biz+C%22">Biz C</searchLink>; Orthopedics and Orthopedic Oncology, Department of Surgery, Oncology and Gastroenterology (DiSCOG), University-Hospital of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Manni+S%22">Manni S</searchLink>; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy.; Laboratory of Myeloma and Lymphoma Pathobiology, Veneto Institute of Molecular Medicine (VIMM), Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Pizzi+M%22">Pizzi M</searchLink>; Pathology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Pianalto+S%22">Pianalto S</searchLink>; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Zoletto+S%22">Zoletto S</searchLink>; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Carabotta+V%22">Carabotta V</searchLink>; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Danesin+N%22">Danesin N</searchLink>; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Ruggieri+P%22">Ruggieri P</searchLink>; Orthopedics and Orthopedic Oncology, Department of Surgery, Oncology and Gastroenterology (DiSCOG), University-Hospital of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Dei+Tos+AP%22">Dei Tos AP</searchLink>; Pathology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Piazza+F%22">Piazza F</searchLink>; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy.; Laboratory of Myeloma and Lymphoma Pathobiology, Veneto Institute of Molecular Medicine (VIMM), Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Trentin+L%22">Trentin L</searchLink>; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Vianello+F%22">Vianello F</searchLink>; Hematology Unit, Department of Medicine-DIMED, University-Hospital of Padua, Padua, Italy. fabrizio.vianello@unipd.it.
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