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Decoding and Overcoming Temozolomide Resistance Through CRISPR/Cas Technologies.

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Title: Decoding and Overcoming Temozolomide Resistance Through CRISPR/Cas Technologies.
Authors: Marques BS; Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal.; Coimbra Chemistry Centre, Institute of Molecular Sciences - IMS, Department of Chemistry, University of Coimbra, Coimbra, Portugal., Mendes M; Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal. mmendes@ff.uc.pt.; Coimbra Chemistry Centre, Institute of Molecular Sciences - IMS, Department of Chemistry, University of Coimbra, Coimbra, Portugal. mmendes@ff.uc.pt., Alves JL; Department of Neurosurgery, ULS Coimbra, Coimbra, Portugal.; Instituto Português de Oncologia, Coimbra, Portugal.; Coimbra Institute for Clinical and Biomedical Research, iCBR, Faculty of Medicine, University of Coimbra, Coimbra, Portugal., Pais A; Coimbra Chemistry Centre, Institute of Molecular Sciences - IMS, Department of Chemistry, University of Coimbra, Coimbra, Portugal., Vitorino C; Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal. csvitorino@ff.uc.pt.; Coimbra Chemistry Centre, Institute of Molecular Sciences - IMS, Department of Chemistry, University of Coimbra, Coimbra, Portugal. csvitorino@ff.uc.pt.
Source: Molecular diagnosis & therapy [Mol Diagn Ther] 2026 Jul 15. Date of Electronic Publication: 2026 Jul 15.
Publication Type: Journal Article; Review
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 101264260 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-2000 (Electronic) Linking ISSN: 11771062 NLM ISO Abbreviation: Mol Diagn Ther Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Marques+BS%22">Marques BS</searchLink>; Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal.; Coimbra Chemistry Centre, Institute of Molecular Sciences - IMS, Department of Chemistry, University of Coimbra, Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Mendes+M%22">Mendes M</searchLink>; Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal. mmendes@ff.uc.pt.; Coimbra Chemistry Centre, Institute of Molecular Sciences - IMS, Department of Chemistry, University of Coimbra, Coimbra, Portugal. mmendes@ff.uc.pt.<br /><searchLink fieldCode="AU" term="%22Alves+JL%22">Alves JL</searchLink>; Department of Neurosurgery, ULS Coimbra, Coimbra, Portugal.; Instituto Português de Oncologia, Coimbra, Portugal.; Coimbra Institute for Clinical and Biomedical Research, iCBR, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Pais+A%22">Pais A</searchLink>; Coimbra Chemistry Centre, Institute of Molecular Sciences - IMS, Department of Chemistry, University of Coimbra, Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Vitorino+C%22">Vitorino C</searchLink>; Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal. csvitorino@ff.uc.pt.; Coimbra Chemistry Centre, Institute of Molecular Sciences - IMS, Department of Chemistry, University of Coimbra, Coimbra, Portugal. csvitorino@ff.uc.pt.
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        Value: 10.1007/s40291-026-00864-3
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              Text: 2026 Jul 15
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