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Survival estimates and their predictors in genetic frontotemporal dementia: an international, retrospective, cohort study.

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Title: Survival estimates and their predictors in genetic frontotemporal dementia: an international, retrospective, cohort study.
Authors: Bouzigues A; Department of Neurodegenerative Disease, Dementia Research Centre, UCL Queen Square Institute of Neurology, London, UK; Department of Psychiatry, Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada. Electronic address: arabella.bouzigues.18@ucl.ac.uk., Grassi M; Statistic Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy., Cantoni V; Department of Clinical and Experimental Sciences, University of Brescia, Italy., Premi E; Stroke Unit, ASST Spedali Civili Brescia, Brescia, Italy., Bellini S; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy., Binetti G; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy., Logroscino G; Center for Neurodegenerative Diseases and the Aging Brain, Department of Clinical Research in Neurology, University of Bari 'Aldo Moro', 'Pia Fondazione Cardinale G Panico', Tricase, Lecce, Italy., Russell LL; Department of Neurodegenerative Disease, Dementia Research Centre, UCL Queen Square Institute of Neurology, London, UK., Ferry-Bolder E; Department of Neurodegenerative Disease, Dementia Research Centre, UCL Queen Square Institute of Neurology, London, UK., Foster PH; Department of Neurodegenerative Disease, Dementia Research Centre, UCL Queen Square Institute of Neurology, London, UK., van Swieten JC; Department of Neurology, Erasmus Medical Centre, Rotterdam, Netherlands., Jiskoot LC; Department of Neurology, Erasmus Medical Centre, Rotterdam, Netherlands., Seelaar H; Department of Neurology, Erasmus Medical Centre, Rotterdam, Netherlands., Sanchez-Valle R; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic, Institut d'Investigacións Biomèdiques August Pi I Sunyer, University of Barcelona, Barcelona, Spain., Laforce R; Clinique Interdisciplinaire de Mémoire, Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Québec City, QC, Canada., Graff C; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Bioclinicum, Karolinska Institutet, Solna, Sweden; Unit for Hereditary Dementias, Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden., Galimberti D; Fondazione Ca' Granda, IRCCS Ospedale Policlinico, Milan, Italy; Centro Dino Ferrari, University of Milan, Milan, Italy., Vandenberghe R; Laboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Leuven, Belgium; Neurology Service, University Hospitals Leuven, Leuven, Belgium; Leuven Brain Institute, KU Leuven, Leuven, Belgium., de Mendonça A; Faculty of Medicine, University of Lisbon, Lisbon, Portugal., Di Fede G; Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy., Santana I; Neurology Service, Faculty of Medicine, University Hospital of Coimbra, University of Coimbra, Coimbra, Portugal; Center for Neuroscience and Cell Biology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal., Gerhard A; Division of Psychology Communication and Human Neuroscience, Wolfson Molecular Imaging Centre, University of Manchester, Manchester, UK; Department of Nuclear Medicine, Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen, Essen, Germany; Department of Geriatric Medicine, Klinikum Hochsauerland, Arnsberg, Germany., Langheinrich T; Greater Manchester Neuroscience Centre, Salford, UK; Division of Psychology, Communication and Human Neuroscience, University of Manchester, Manchester, UK., Levin J; Department of Neurology, Ludwig-Maximilians Universität München, Munich 80539, Germany; German Center for Neurodegenerative Diseases, Munich, Germany; Munich Cluster of Systems Neurology, Munich, Germany., Nacmias B; Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy; IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy., Otto M; Department of Neurology, University of Ulm, Ulm, Germany., Bertoux M; Lille Neuroscience & Cognition U1172, University of Lille, Inserm, CHU Lille, Lille, France., Lebouvier T; Lille Neuroscience & Cognition U1172, University of Lille, Inserm, CHU Lille, Lille, France., Ducharme S; Department of Psychiatry, Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada; McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, QC, Canada., Butler C; Nuffield Department of Clinical Neurosciences, Medical Sciences Division, University of Oxford, Oxford, UK; Department of Brain Sciences, Imperial College London, London, UK., le Ber I; Département de Neurologie, AP-HP-Hôpital Pitié-Salpêtrière, Centre de référence des démences rares ou précoces, IM2A, Paris, France., Bruffaerts R; Department of Psychiatry, Centre for Public Health Psychiatry, KU Leuven, Leuven, Belgium; Campus Gasthuisberg, Universitair Psychiatrisch Centrum KU Leuven, Leuven, Belgium., Solje E; Institute of Clinical Medicine - Neurology, University of Eastern Finland, Kuopio, Finland; Neuro Center-Neurology, Kuopio University Hospital, Kuopio, Finland., Kinnunen M; Institute of Clinical Medicine - Neurology, University of Eastern Finland, Kuopio, Finland; Neuro Center-Neurology, Kuopio University Hospital, Kuopio, Finland., Krüger J; Research Unit of Clinical Medicine, Neurology, University of Oulu, Oulu, Finland; MRC, Oulu University Hospital, Oulu, Finland; Neurocenter, Neurology, Oulu University Hospital, Oulu, Finland., Finger E; Department of Clinical Neurological Sciences, University of Western Ontario, London, ON, Canada., Tartaglia MC; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON, Canada., Masellis M; Sunnybrook Health Sciences Centre, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada., Rowe JB; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge, UK., Synofzik M; Department of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Tübingen, Germany; Center for Neurodegenerative Diseases, Tübingen, Germany., Moreno F; Cognitive Disorders Unit, Department of Neurology, Hospital Universitario Donostia, San Sebastian, Spain; Neurosciences Area, Group of Neurodegenerative Diseases, Biogipuzkoa Health Research Institute, San Sebastian, Spain; Center for Biomedical Research in Neurodegenerative Disease, Carlos III Health Institute, Madrid, Spain., Ghidoni R; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy., Migliaccio R; Département de Neurologie, AP-HP-Hôpital Pitié-Salpêtrière, Centre de référence des démences rares ou précoces, IM2A, Paris, France., Rohrer JD; Department of Neurodegenerative Disease, Dementia Research Centre, UCL Queen Square Institute of Neurology, London, UK., Borroni B; Department of Clinical and Experimental Sciences, University of Brescia, Italy; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy. Electronic address: bborroni@inwind.it.
Corporate Authors: GENFI consortium
Source: The Lancet. Neurology [Lancet Neurol] 2026 Aug; Vol. 25 (8), pp. 731-740.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 101139309 Publication Model: Print Cited Medium: Internet ISSN: 1474-4465 (Electronic) Linking ISSN: 14744422 NLM ISO Abbreviation: Lancet Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Survival estimates and their predictors in genetic frontotemporal dementia: an international, retrospective, cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Bouzigues+A%22">Bouzigues A</searchLink>; Department of Neurodegenerative Disease, Dementia Research Centre, UCL Queen Square Institute of Neurology, London, UK; Department of Psychiatry, Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada. Electronic address: arabella.bouzigues.18@ucl.ac.uk.<br /><searchLink fieldCode="AU" term="%22Grassi+M%22">Grassi M</searchLink>; Statistic Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Cantoni+V%22">Cantoni V</searchLink>; Department of Clinical and Experimental Sciences, University of Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Premi+E%22">Premi E</searchLink>; Stroke Unit, ASST Spedali Civili Brescia, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Bellini+S%22">Bellini S</searchLink>; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Binetti+G%22">Binetti G</searchLink>; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Logroscino+G%22">Logroscino G</searchLink>; Center for Neurodegenerative Diseases and the Aging Brain, Department of Clinical Research in Neurology, University of Bari 'Aldo Moro', 'Pia Fondazione Cardinale G Panico', Tricase, Lecce, Italy.<br /><searchLink fieldCode="AU" term="%22Russell+LL%22">Russell LL</searchLink>; Department of Neurodegenerative Disease, Dementia Research Centre, UCL Queen Square Institute of Neurology, London, UK.<br /><searchLink fieldCode="AU" term="%22Ferry-Bolder+E%22">Ferry-Bolder E</searchLink>; Department of Neurodegenerative Disease, Dementia Research Centre, UCL Queen Square Institute of Neurology, London, UK.<br /><searchLink fieldCode="AU" term="%22Foster+PH%22">Foster PH</searchLink>; Department of Neurodegenerative Disease, Dementia Research Centre, UCL Queen Square Institute of Neurology, London, UK.<br /><searchLink fieldCode="AU" term="%22van+Swieten+JC%22">van Swieten JC</searchLink>; Department of Neurology, Erasmus Medical Centre, Rotterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Jiskoot+LC%22">Jiskoot LC</searchLink>; Department of Neurology, Erasmus Medical Centre, Rotterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Seelaar+H%22">Seelaar H</searchLink>; Department of Neurology, Erasmus Medical Centre, Rotterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Sanchez-Valle+R%22">Sanchez-Valle R</searchLink>; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic, Institut d'Investigacións Biomèdiques August Pi I Sunyer, University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Laforce+R%22">Laforce R</searchLink>; Clinique Interdisciplinaire de Mémoire, Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Québec City, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Graff+C%22">Graff C</searchLink>; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Bioclinicum, Karolinska Institutet, Solna, Sweden; Unit for Hereditary Dementias, Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden.<br /><searchLink fieldCode="AU" term="%22Galimberti+D%22">Galimberti D</searchLink>; Fondazione Ca' Granda, IRCCS Ospedale Policlinico, Milan, Italy; Centro Dino Ferrari, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Vandenberghe+R%22">Vandenberghe R</searchLink>; Laboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Leuven, Belgium; Neurology Service, University Hospitals Leuven, Leuven, Belgium; Leuven Brain Institute, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22de+Mendonça+A%22">de Mendonça A</searchLink>; Faculty of Medicine, University of Lisbon, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Di+Fede+G%22">Di Fede G</searchLink>; Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Santana+I%22">Santana I</searchLink>; Neurology Service, Faculty of Medicine, University Hospital of Coimbra, University of Coimbra, Coimbra, Portugal; Center for Neuroscience and Cell Biology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Gerhard+A%22">Gerhard A</searchLink>; Division of Psychology Communication and Human Neuroscience, Wolfson Molecular Imaging Centre, University of Manchester, Manchester, UK; Department of Nuclear Medicine, Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen, Essen, Germany; Department of Geriatric Medicine, Klinikum Hochsauerland, Arnsberg, Germany.<br /><searchLink fieldCode="AU" term="%22Langheinrich+T%22">Langheinrich T</searchLink>; Greater Manchester Neuroscience Centre, Salford, UK; Division of Psychology, Communication and Human Neuroscience, University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Levin+J%22">Levin J</searchLink>; Department of Neurology, Ludwig-Maximilians Universität München, Munich 80539, Germany; German Center for Neurodegenerative Diseases, Munich, Germany; Munich Cluster of Systems Neurology, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Nacmias+B%22">Nacmias B</searchLink>; Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy; IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Otto+M%22">Otto M</searchLink>; Department of Neurology, University of Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Bertoux+M%22">Bertoux M</searchLink>; Lille Neuroscience & Cognition U1172, University of Lille, Inserm, CHU Lille, Lille, France.<br /><searchLink fieldCode="AU" term="%22Lebouvier+T%22">Lebouvier T</searchLink>; Lille Neuroscience & Cognition U1172, University of Lille, Inserm, CHU Lille, Lille, France.<br /><searchLink fieldCode="AU" term="%22Ducharme+S%22">Ducharme S</searchLink>; Department of Psychiatry, Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada; McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Butler+C%22">Butler C</searchLink>; Nuffield Department of Clinical Neurosciences, Medical Sciences Division, University of Oxford, Oxford, UK; Department of Brain Sciences, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22le+Ber+I%22">le Ber I</searchLink>; Département de Neurologie, AP-HP-Hôpital Pitié-Salpêtrière, Centre de référence des démences rares ou précoces, IM2A, Paris, France.<br /><searchLink fieldCode="AU" term="%22Bruffaerts+R%22">Bruffaerts R</searchLink>; Department of Psychiatry, Centre for Public Health Psychiatry, KU Leuven, Leuven, Belgium; Campus Gasthuisberg, Universitair Psychiatrisch Centrum KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Solje+E%22">Solje E</searchLink>; Institute of Clinical Medicine - Neurology, University of Eastern Finland, Kuopio, Finland; Neuro Center-Neurology, Kuopio University Hospital, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Kinnunen+M%22">Kinnunen M</searchLink>; Institute of Clinical Medicine - Neurology, University of Eastern Finland, Kuopio, Finland; Neuro Center-Neurology, Kuopio University Hospital, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Krüger+J%22">Krüger J</searchLink>; Research Unit of Clinical Medicine, Neurology, University of Oulu, Oulu, Finland; MRC, Oulu University Hospital, Oulu, Finland; Neurocenter, Neurology, Oulu University Hospital, Oulu, Finland.<br /><searchLink fieldCode="AU" term="%22Finger+E%22">Finger E</searchLink>; Department of Clinical Neurological Sciences, University of Western Ontario, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Tartaglia+MC%22">Tartaglia MC</searchLink>; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Masellis+M%22">Masellis M</searchLink>; Sunnybrook Health Sciences Centre, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Rowe+JB%22">Rowe JB</searchLink>; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Synofzik+M%22">Synofzik M</searchLink>; Department of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Tübingen, Germany; Center for Neurodegenerative Diseases, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Moreno+F%22">Moreno F</searchLink>; Cognitive Disorders Unit, Department of Neurology, Hospital Universitario Donostia, San Sebastian, Spain; Neurosciences Area, Group of Neurodegenerative Diseases, Biogipuzkoa Health Research Institute, San Sebastian, Spain; Center for Biomedical Research in Neurodegenerative Disease, Carlos III Health Institute, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Ghidoni+R%22">Ghidoni R</searchLink>; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Migliaccio+R%22">Migliaccio R</searchLink>; Département de Neurologie, AP-HP-Hôpital Pitié-Salpêtrière, Centre de référence des démences rares ou précoces, IM2A, Paris, France.<br /><searchLink fieldCode="AU" term="%22Rohrer+JD%22">Rohrer JD</searchLink>; Department of Neurodegenerative Disease, Dementia Research Centre, UCL Queen Square Institute of Neurology, London, UK.<br /><searchLink fieldCode="AU" term="%22Borroni+B%22">Borroni B</searchLink>; Department of Clinical and Experimental Sciences, University of Brescia, Italy; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy. Electronic address: bborroni@inwind.it.
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            – Type: issn-electronic
              Value: 1474-4465
          Numbering:
            – Type: volume
              Value: 25
            – Type: issue
              Value: 8
          Titles:
            – TitleFull: The Lancet. Neurology
              Type: main
ResultId 1