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Assessment of differentially culturable tubercle bacteria assays for the detection of tuberculosis infection in asymptomatic household contacts and the implications for intra-household transmission: a longitudinal cohort study.

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Title: Assessment of differentially culturable tubercle bacteria assays for the detection of tuberculosis infection in asymptomatic household contacts and the implications for intra-household transmission: a longitudinal cohort study.
Authors: Sewcharran A; Department of Science and Innovation-National Research Foundation Centre of Excellence for Biomedical TB Research, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand and the National Health Laboratory Service, Johannesburg, South Africa., Gordhan BG; Department of Science and Innovation-National Research Foundation Centre of Excellence for Biomedical TB Research, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand and the National Health Laboratory Service, Johannesburg, South Africa., Tang L; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City, NY, USA., Keenan S; Department of Science and Innovation-National Research Foundation Centre of Excellence for Biomedical TB Research, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand and the National Health Laboratory Service, Johannesburg, South Africa., Patel D; Department of Science and Innovation-National Research Foundation Centre of Excellence for Biomedical TB Research, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand and the National Health Laboratory Service, Johannesburg, South Africa., Mofokeng NJ; Perinatal HIV Research Unit (PHRU), Infectious Diseases and Oncology Research Institute, University of the Witwatersrand, Johannesburg, South Africa., Ncwana B; Perinatal HIV Research Unit (PHRU), Infectious Diseases and Oncology Research Institute, University of the Witwatersrand, Johannesburg, South Africa., Waja Z; Perinatal HIV Research Unit (PHRU), Infectious Diseases and Oncology Research Institute, University of the Witwatersrand, Johannesburg, South Africa., Mathema B; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City, NY, USA., Martinson N; Perinatal HIV Research Unit (PHRU), Infectious Diseases and Oncology Research Institute, University of the Witwatersrand, Johannesburg, South Africa; Johns Hopkins University Centre for TB Research, Baltimore, MD, USA., Kana BD; Department of Science and Innovation-National Research Foundation Centre of Excellence for Biomedical TB Research, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand and the National Health Laboratory Service, Johannesburg, South Africa. Electronic address: bavesh.kana@wits.ac.za.
Source: The Lancet. Microbe [Lancet Microbe] 2026 Jul 15, pp. 101412. Date of Electronic Publication: 2026 Jul 15.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101769019 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-5247 (Electronic) Linking ISSN: 26665247 NLM ISO Abbreviation: Lancet Microbe Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Sewcharran+A%22">Sewcharran A</searchLink>; Department of Science and Innovation-National Research Foundation Centre of Excellence for Biomedical TB Research, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand and the National Health Laboratory Service, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Gordhan+BG%22">Gordhan BG</searchLink>; Department of Science and Innovation-National Research Foundation Centre of Excellence for Biomedical TB Research, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand and the National Health Laboratory Service, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Tang+L%22">Tang L</searchLink>; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Keenan+S%22">Keenan S</searchLink>; Department of Science and Innovation-National Research Foundation Centre of Excellence for Biomedical TB Research, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand and the National Health Laboratory Service, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Patel+D%22">Patel D</searchLink>; Department of Science and Innovation-National Research Foundation Centre of Excellence for Biomedical TB Research, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand and the National Health Laboratory Service, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Mofokeng+NJ%22">Mofokeng NJ</searchLink>; Perinatal HIV Research Unit (PHRU), Infectious Diseases and Oncology Research Institute, University of the Witwatersrand, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Ncwana+B%22">Ncwana B</searchLink>; Perinatal HIV Research Unit (PHRU), Infectious Diseases and Oncology Research Institute, University of the Witwatersrand, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Waja+Z%22">Waja Z</searchLink>; Perinatal HIV Research Unit (PHRU), Infectious Diseases and Oncology Research Institute, University of the Witwatersrand, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Mathema+B%22">Mathema B</searchLink>; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Martinson+N%22">Martinson N</searchLink>; Perinatal HIV Research Unit (PHRU), Infectious Diseases and Oncology Research Institute, University of the Witwatersrand, Johannesburg, South Africa; Johns Hopkins University Centre for TB Research, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kana+BD%22">Kana BD</searchLink>; Department of Science and Innovation-National Research Foundation Centre of Excellence for Biomedical TB Research, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand and the National Health Laboratory Service, Johannesburg, South Africa. Electronic address: bavesh.kana@wits.ac.za.
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  Data: <searchLink fieldCode="JN" term="%22101769019%22">The Lancet. Microbe</searchLink> [Lancet Microbe] 2026 Jul 15, pp. 101412. <i>Date of Electronic Publication: </i>2026 Jul 15.
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              Text: 2026 Jul 15
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