EAU-EANM-ESTRO-ESUR-ISUP-SIOG Guidelines on Prostate Cancer. Part II-2026 Update: Treatment of Relapsing and Metastatic Prostate Cancer.

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Title: EAU-EANM-ESTRO-ESUR-ISUP-SIOG Guidelines on Prostate Cancer. Part II-2026 Update: Treatment of Relapsing and Metastatic Prostate Cancer.
Authors: Tilki D; Martini-Klinik Prostate Cancer Center, University Hospital Hamburg Eppendorf, Hamburg, Germany; Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany; Department of Urology, Koc University Hospital, Istanbul, Türkiye. Electronic address: derya.tilki@uke.de., van den Bergh RCN; Department of Urology, Erasmus University Medical Center, Rotterdam, The Netherlands., Briers E; Europa Uomo, Antwerp, Belgium., Chiu P; S.H. Ho Urology Centre, Department of Surgery, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China., Eberli D; Department of Urology, University Hospital Zurich, Zurich, Switzerland., Epure A; Department of Imaging, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France; Université de Lyon, Université Lyon 1, UFR Lyon-Est, Lyon France., Farolfi A; Nuclear Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Fonteyne V; Department of Radiation Oncology, Ghent University, Ghent, Belgium., Gandaglia G; Division of Oncology/Unit of Urology, Soldera Prostate Cancer Laboratory, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy., Gillessen S; Oncology Institute of Southern Switzerland (IOSI), EOC, Bellinzona and Faculty of Biomedical Sciences, USI, Lugano, Switzerland., Grivas N; Department of Urology, Lefkos Stavros-The Athens Clinic, Athens, Greece., Henry AM; Leeds Cancer Centre, St. James's University Hospital and University of Leeds, Leeds, UK., van Leenders GJLH; Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands., Espinos EL; Department of Urology, University Hospital La Paz, Madrid, Spain., Madsen B; Europa Uomo, Antwerp, Belgium., Oldenburg J; Department of Oncology, Akershus University Hospital (Ahus), Lørenskog, Norway; Faculty of Medicine, University of Oslo, Oslo, Norway., van Oort IM; Department of Urology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Oprea-Lager DE; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands., Roberts MJ; Department of Urology, Royal Brisbane and Women's Hospital, Brisbane, Australia; Faculty of Medicine, The University of Queensland Centre for Clinical Research, Herston, QLD, Australia., Rouvière O; Department of Imaging, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France., Sachdeva A; Division of Cancer Sciences, University of Manchester, Manchester, UK., Santis M; Department of Urology, Universitätsmedizin Berlin, Berlin, Germany; Department of Urology, Medical University of Vienna, Vienna, Austria., Schoots IG; Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Radiology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Smith EJ; European Association of Urology, Arnhem, Netherlands., Stranne J; Department of Urology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Urology, Sahlgrenska University Hospital-Västra Götaland, Gothenburg, Sweden., Wiegel T; Department of Radiation Oncology, University Hospital Ulm, Ulm, Germany., Cornford P; Department of Urology, Bon Secours Hospital, Cork Ireland and University College Cork.
Source: European urology [Eur Urol] 2026 Jul 15. Date of Electronic Publication: 2026 Jul 15.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Switzerland NLM ID: 7512719 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7560 (Electronic) Linking ISSN: 03022838 NLM ISO Abbreviation: Eur Urol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Tilki+D%22">Tilki D</searchLink>; Martini-Klinik Prostate Cancer Center, University Hospital Hamburg Eppendorf, Hamburg, Germany; Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany; Department of Urology, Koc University Hospital, Istanbul, Türkiye. Electronic address: derya.tilki@uke.de.<br /><searchLink fieldCode="AU" term="%22van+den+Bergh+RCN%22">van den Bergh RCN</searchLink>; Department of Urology, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Briers+E%22">Briers E</searchLink>; Europa Uomo, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Chiu+P%22">Chiu P</searchLink>; S.H. Ho Urology Centre, Department of Surgery, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Eberli+D%22">Eberli D</searchLink>; Department of Urology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Epure+A%22">Epure A</searchLink>; Department of Imaging, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France; Université de Lyon, Université Lyon 1, UFR Lyon-Est, Lyon France.<br /><searchLink fieldCode="AU" term="%22Farolfi+A%22">Farolfi A</searchLink>; Nuclear Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Fonteyne+V%22">Fonteyne V</searchLink>; Department of Radiation Oncology, Ghent University, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Gandaglia+G%22">Gandaglia G</searchLink>; Division of Oncology/Unit of Urology, Soldera Prostate Cancer Laboratory, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gillessen+S%22">Gillessen S</searchLink>; Oncology Institute of Southern Switzerland (IOSI), EOC, Bellinzona and Faculty of Biomedical Sciences, USI, Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Grivas+N%22">Grivas N</searchLink>; Department of Urology, Lefkos Stavros-The Athens Clinic, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Henry+AM%22">Henry AM</searchLink>; Leeds Cancer Centre, St. James's University Hospital and University of Leeds, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22van+Leenders+GJLH%22">van Leenders GJLH</searchLink>; Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Espinos+EL%22">Espinos EL</searchLink>; Department of Urology, University Hospital La Paz, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Madsen+B%22">Madsen B</searchLink>; Europa Uomo, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Oldenburg+J%22">Oldenburg J</searchLink>; Department of Oncology, Akershus University Hospital (Ahus), Lørenskog, Norway; Faculty of Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22van+Oort+IM%22">van Oort IM</searchLink>; Department of Urology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Oprea-Lager+DE%22">Oprea-Lager DE</searchLink>; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Roberts+MJ%22">Roberts MJ</searchLink>; Department of Urology, Royal Brisbane and Women's Hospital, Brisbane, Australia; Faculty of Medicine, The University of Queensland Centre for Clinical Research, Herston, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Rouvière+O%22">Rouvière O</searchLink>; Department of Imaging, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Sachdeva+A%22">Sachdeva A</searchLink>; Division of Cancer Sciences, University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Santis+M%22">Santis M</searchLink>; Department of Urology, Universitätsmedizin Berlin, Berlin, Germany; Department of Urology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Schoots+IG%22">Schoots IG</searchLink>; Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Radiology, Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Smith+EJ%22">Smith EJ</searchLink>; European Association of Urology, Arnhem, Netherlands.<br /><searchLink fieldCode="AU" term="%22Stranne+J%22">Stranne J</searchLink>; Department of Urology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Urology, Sahlgrenska University Hospital-Västra Götaland, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Wiegel+T%22">Wiegel T</searchLink>; Department of Radiation Oncology, University Hospital Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Cornford+P%22">Cornford P</searchLink>; Department of Urology, Bon Secours Hospital, Cork Ireland and University College Cork.
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