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Caspase-3 cleaves CYLD to restrict interferon signaling during mitochondrial apoptosis.

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Title: Caspase-3 cleaves CYLD to restrict interferon signaling during mitochondrial apoptosis.
Authors: Macé YM; Team SOAP, CRCI²NA, INSERM, CNRS, Université de Nantes, Nantes, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France., Douanne T; Team SOAP, CRCI²NA, INSERM, CNRS, Université de Nantes, Nantes, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France., Jardine J; Team SOAP, CRCI²NA, INSERM, CNRS, Université de Nantes, Nantes, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France., Trillet K; Team SOAP, CRCI²NA, INSERM, CNRS, Université de Nantes, Nantes, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France., Moreau R; Team SOAP, CRCI²NA, INSERM, CNRS, Université de Nantes, Nantes, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France., Re J; Institut de Génétique Moléculaire de Montpellier (IGMM), Université de Montpellier, CNRS UMR5535, Montpellier, France., Ellison CJ; Department of Biochemistry, University of Oxford, Oxford, UK., Laguette N; Institut de Génétique Moléculaire de Montpellier (IGMM), Université de Montpellier, CNRS UMR5535, Montpellier, France., Elliott PR; Department of Biochemistry, University of Oxford, Oxford, UK., Gavard J; Team SOAP, CRCI²NA, INSERM, CNRS, Université de Nantes, Nantes, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France.; Institut de Cancérologie de l'Ouest (ICO), Saint-Herblain, France., Bidère N; Team SOAP, CRCI²NA, INSERM, CNRS, Université de Nantes, Nantes, France. nicolas.bidere@inserm.fr.; Equipe Labellisée Ligue Contre le Cancer, Paris, France. nicolas.bidere@inserm.fr.
Source: EMBO reports [EMBO Rep] 2026 Jul 15. Date of Electronic Publication: 2026 Jul 15.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Macé+YM%22">Macé YM</searchLink>; Team SOAP, CRCI²NA, INSERM, CNRS, Université de Nantes, Nantes, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France.<br /><searchLink fieldCode="AU" term="%22Douanne+T%22">Douanne T</searchLink>; Team SOAP, CRCI²NA, INSERM, CNRS, Université de Nantes, Nantes, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France.<br /><searchLink fieldCode="AU" term="%22Jardine+J%22">Jardine J</searchLink>; Team SOAP, CRCI²NA, INSERM, CNRS, Université de Nantes, Nantes, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France.<br /><searchLink fieldCode="AU" term="%22Trillet+K%22">Trillet K</searchLink>; Team SOAP, CRCI²NA, INSERM, CNRS, Université de Nantes, Nantes, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France.<br /><searchLink fieldCode="AU" term="%22Moreau+R%22">Moreau R</searchLink>; Team SOAP, CRCI²NA, INSERM, CNRS, Université de Nantes, Nantes, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France.<br /><searchLink fieldCode="AU" term="%22Re+J%22">Re J</searchLink>; Institut de Génétique Moléculaire de Montpellier (IGMM), Université de Montpellier, CNRS UMR5535, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Ellison+CJ%22">Ellison CJ</searchLink>; Department of Biochemistry, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Laguette+N%22">Laguette N</searchLink>; Institut de Génétique Moléculaire de Montpellier (IGMM), Université de Montpellier, CNRS UMR5535, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Elliott+PR%22">Elliott PR</searchLink>; Department of Biochemistry, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Gavard+J%22">Gavard J</searchLink>; Team SOAP, CRCI²NA, INSERM, CNRS, Université de Nantes, Nantes, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France.; Institut de Cancérologie de l'Ouest (ICO), Saint-Herblain, France.<br /><searchLink fieldCode="AU" term="%22Bidère+N%22">Bidère N</searchLink>; Team SOAP, CRCI²NA, INSERM, CNRS, Université de Nantes, Nantes, France. nicolas.bidere@inserm.fr.; Equipe Labellisée Ligue Contre le Cancer, Paris, France. nicolas.bidere@inserm.fr.
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