Comparative Evaluation of Rituximab Versus Approved Therapies in Aquaporin-4-IgG-Positive Neuromyelitis Optica Spectrum Disorder: A Systematic Review and Network Meta-analysis.
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| Title: | Comparative Evaluation of Rituximab Versus Approved Therapies in Aquaporin-4-IgG-Positive Neuromyelitis Optica Spectrum Disorder: A Systematic Review and Network Meta-analysis. |
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| Authors: | Barzegar M; Department of Neurology, Toledo University, Toledo, OH, USA., Samadzadeh S; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.; Institute of Regional Health Research & Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Department of Neurology, Slagelse Hospitals, Slagelse, Denmark., Audoin B; APHM, Hôpital de la Timone, Pôle de Neurosciences Cliniques, Service de Neurologie, Marseille, France.; Department of Neurology, University Hospital of Marseille, Aix-Marseille University, CNRS, CRMBM, Marseille, France., Berthele A; Department of Neurology, School of Medicine and Health, Technical University Munich, Klinikum Rechts der Isar, Munich, Germany., Altintas A; Neurology Department, School of Medicine, Koç University, Istanbul, Turkey.; Koç University Research Center for Translational Medicine (KUTTAM), Istanbul, Turkey., Willekens B; Department of Neurology, Antwerp University Hospital, University of Antwerp, Edegem, Belgium.; Translational Sciences Research Group, Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.; Laboratory of Experimental Haematology, VAXINFECTIO, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium., Laakso S; Neurocenter, Helsinki University Hospital, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland., Jahani S; Institute of Regional Health Research & Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Department of Neurology, Slagelse Hospitals, Slagelse, Denmark., Papp V; Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital-Rigshospitalet, 2600, Glostrup, Denmark., Zappe C; Department of Neurology, School of Medicine and Health, Technical University Munich, Klinikum Rechts der Isar, Munich, Germany., Lefter A; Department of Neurology, Antwerp University Hospital, University of Antwerp, Edegem, Belgium.; Translational Sciences Research Group, Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.; Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK., Siva A; Department of Neurology, Istanbul University-Cerrahpaşa Faculty of Medicine, Istanbul, Turkey., Afshari-Safavi A; Institute of Regional Health Research & Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Department of Neurology, Slagelse Hospitals, Slagelse, Denmark., Möller S; Open Patient Data Explorative Network, Odense University Hospital, University of Southern Denmark, Odense, Denmark., Wokke B; Department of Neurology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Cortese R; Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy., Illes Z; Department of Neurology, Odense University Hospital, Odense, Denmark., Huda S; Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.; Department of Neurology, The Walton Centre NHS Foundation Trust, Liverpool, UK., Paulus R; Department of Neurology, Medical University of Vienna, Vienna, Austria., Messina S; Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK., Collongues N; Department of Neurology, University Hospital of Strasbourg, Strasbourg, France.; Department of Pharmacology, Addictology, Toxicology, and Therapeutics, Strasbourg University, Strasbourg, France., Ringelstein M; Department of Neurology, University Clinic and Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; Department of Neurology, Center for Neurology and Neuropsychiatry, LVR-Klinikum, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany., Cobo-Calvo Á; Neurology-Neuroimmunology Department, Multiple Sclerosis Centre of Catalonia (Cemcat), Vall d'Hebron Barcelona Hospital Campus, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain., Hacohen Y; Department of Neurology, Great Ormond Street Hospital for Children, London, UK.; Department of Neuroinflammation, UCL Institute of Neurology, University College London, London, UK., Arrambide G; Neurology-Neuroimmunology Department, Multiple Sclerosis Centre of Catalonia (Cemcat), Vall d'Hebron Barcelona Hospital Campus, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain., Palace J; Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK., Mariotto S; Neurology Unit, Department of Neurosciences, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy., Marignier R; Hospices Civils de Lyon, Service de Neurologie, Sclérose en Plaques, Pathologies de la Myéline et Neuro-Inflammation, Hôpital Neurologique Pierre Wertheimer, Bron Cedex, France., Geraldes R; Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK., Paul F; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.; Neuroscience Clinical Research Center, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Asgari N; Institute of Regional Health Research & Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark. nasgari@health.sdu.dk.; Department of Neurology, Slagelse Hospitals, Slagelse, Denmark. nasgari@health.sdu.dk.; Department of Regional Health Research & Molecular Medicine, University of Southern Denmark, Campusvej 55, 5230, Odense, Denmark. nasgari@health.sdu.dk. |
| Corporate Authors: | MEDEN study group |
| Source: | Neurology and therapy [Neurol Ther] 2026 Jul 16. Date of Electronic Publication: 2026 Jul 16. |
| Publication Type: | Journal Article; Review |
| Journal Info: | Publisher: Springer Country of Publication: New Zealand NLM ID: 101637818 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2193-8253 (Print) Linking ISSN: 21936536 NLM ISO Abbreviation: Neurol Ther |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42458195 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Comparative Evaluation of Rituximab Versus Approved Therapies in Aquaporin-4-IgG-Positive Neuromyelitis Optica Spectrum Disorder: A Systematic Review and Network Meta-analysis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Barzegar+M%22">Barzegar M</searchLink>; Department of Neurology, Toledo University, Toledo, OH, USA.<br /><searchLink fieldCode="AU" term="%22Samadzadeh+S%22">Samadzadeh S</searchLink>; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.; Institute of Regional Health Research & Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Department of Neurology, Slagelse Hospitals, Slagelse, Denmark.<br /><searchLink fieldCode="AU" term="%22Audoin+B%22">Audoin B</searchLink>; APHM, Hôpital de la Timone, Pôle de Neurosciences Cliniques, Service de Neurologie, Marseille, France.; Department of Neurology, University Hospital of Marseille, Aix-Marseille University, CNRS, CRMBM, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Berthele+A%22">Berthele A</searchLink>; Department of Neurology, School of Medicine and Health, Technical University Munich, Klinikum Rechts der Isar, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Altintas+A%22">Altintas A</searchLink>; Neurology Department, School of Medicine, Koç University, Istanbul, Turkey.; Koç University Research Center for Translational Medicine (KUTTAM), Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Willekens+B%22">Willekens B</searchLink>; Department of Neurology, Antwerp University Hospital, University of Antwerp, Edegem, Belgium.; Translational Sciences Research Group, Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.; Laboratory of Experimental Haematology, VAXINFECTIO, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Laakso+S%22">Laakso S</searchLink>; Neurocenter, Helsinki University Hospital, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Jahani+S%22">Jahani S</searchLink>; Institute of Regional Health Research & Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Department of Neurology, Slagelse Hospitals, Slagelse, Denmark.<br /><searchLink fieldCode="AU" term="%22Papp+V%22">Papp V</searchLink>; Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital-Rigshospitalet, 2600, Glostrup, Denmark.<br /><searchLink fieldCode="AU" term="%22Zappe+C%22">Zappe C</searchLink>; Department of Neurology, School of Medicine and Health, Technical University Munich, Klinikum Rechts der Isar, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Lefter+A%22">Lefter A</searchLink>; Department of Neurology, Antwerp University Hospital, University of Antwerp, Edegem, Belgium.; Translational Sciences Research Group, Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.; Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Siva+A%22">Siva A</searchLink>; Department of Neurology, Istanbul University-Cerrahpaşa Faculty of Medicine, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Afshari-Safavi+A%22">Afshari-Safavi A</searchLink>; Institute of Regional Health Research & Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Department of Neurology, Slagelse Hospitals, Slagelse, Denmark.<br /><searchLink fieldCode="AU" term="%22Möller+S%22">Möller S</searchLink>; Open Patient Data Explorative Network, Odense University Hospital, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Wokke+B%22">Wokke B</searchLink>; Department of Neurology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Cortese+R%22">Cortese R</searchLink>; Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Illes+Z%22">Illes Z</searchLink>; Department of Neurology, Odense University Hospital, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Huda+S%22">Huda S</searchLink>; Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.; Department of Neurology, The Walton Centre NHS Foundation Trust, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Paulus+R%22">Paulus R</searchLink>; Department of Neurology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Messina+S%22">Messina S</searchLink>; Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Collongues+N%22">Collongues N</searchLink>; Department of Neurology, University Hospital of Strasbourg, Strasbourg, France.; Department of Pharmacology, Addictology, Toxicology, and Therapeutics, Strasbourg University, Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Ringelstein+M%22">Ringelstein M</searchLink>; Department of Neurology, University Clinic and Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; Department of Neurology, Center for Neurology and Neuropsychiatry, LVR-Klinikum, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Cobo-Calvo+Á%22">Cobo-Calvo Á</searchLink>; Neurology-Neuroimmunology Department, Multiple Sclerosis Centre of Catalonia (Cemcat), Vall d'Hebron Barcelona Hospital Campus, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Hacohen+Y%22">Hacohen Y</searchLink>; Department of Neurology, Great Ormond Street Hospital for Children, London, UK.; Department of Neuroinflammation, UCL Institute of Neurology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Arrambide+G%22">Arrambide G</searchLink>; Neurology-Neuroimmunology Department, Multiple Sclerosis Centre of Catalonia (Cemcat), Vall d'Hebron Barcelona Hospital Campus, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Palace+J%22">Palace J</searchLink>; Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Mariotto+S%22">Mariotto S</searchLink>; Neurology Unit, Department of Neurosciences, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Marignier+R%22">Marignier R</searchLink>; Hospices Civils de Lyon, Service de Neurologie, Sclérose en Plaques, Pathologies de la Myéline et Neuro-Inflammation, Hôpital Neurologique Pierre Wertheimer, Bron Cedex, France.<br /><searchLink fieldCode="AU" term="%22Geraldes+R%22">Geraldes R</searchLink>; Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Paul+F%22">Paul F</searchLink>; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.; Neuroscience Clinical Research Center, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Asgari+N%22">Asgari N</searchLink>; Institute of Regional Health Research & Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark. nasgari@health.sdu.dk.; Department of Neurology, Slagelse Hospitals, Slagelse, Denmark. nasgari@health.sdu.dk.; Department of Regional Health Research & Molecular Medicine, University of Southern Denmark, Campusvej 55, 5230, Odense, Denmark. nasgari@health.sdu.dk. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22MEDEN+study+group%22">MEDEN study group</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101637818%22">Neurology and therapy</searchLink> [Neurol Ther] 2026 Jul 16. <i>Date of Electronic Publication: </i>2026 Jul 16. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Review – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>101637818 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2193-8253 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221936536%22">21936536 </searchLink><i>NLM ISO Abbreviation: </i>Neurol Ther |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s40120-026-00989-x Languages: – Code: eng Text: English Titles: – TitleFull: Comparative Evaluation of Rituximab Versus Approved Therapies in Aquaporin-4-IgG-Positive Neuromyelitis Optica Spectrum Disorder: A Systematic Review and Network Meta-analysis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Barzegar M – PersonEntity: Name: NameFull: Samadzadeh S – PersonEntity: Name: NameFull: Audoin B – PersonEntity: Name: NameFull: Berthele A – PersonEntity: Name: NameFull: Altintas A – PersonEntity: Name: NameFull: Willekens B – PersonEntity: Name: NameFull: Laakso S – PersonEntity: Name: NameFull: Jahani S – PersonEntity: Name: NameFull: Papp V – PersonEntity: Name: NameFull: Zappe C – PersonEntity: Name: NameFull: Lefter A – PersonEntity: Name: NameFull: Siva A – PersonEntity: Name: NameFull: Afshari-Safavi A – PersonEntity: Name: NameFull: Möller S – PersonEntity: Name: NameFull: Wokke B – PersonEntity: Name: NameFull: Cortese R – PersonEntity: Name: NameFull: Illes Z – PersonEntity: Name: NameFull: Huda S – PersonEntity: Name: NameFull: Paulus R – PersonEntity: Name: NameFull: Messina S – PersonEntity: Name: NameFull: Collongues N – PersonEntity: Name: NameFull: Ringelstein M – PersonEntity: Name: NameFull: Cobo-Calvo Á – PersonEntity: Name: NameFull: Hacohen Y – PersonEntity: Name: NameFull: Arrambide G – PersonEntity: Name: NameFull: Palace J – PersonEntity: Name: NameFull: Mariotto S – PersonEntity: Name: NameFull: Marignier R – PersonEntity: Name: NameFull: Geraldes R – PersonEntity: Name: NameFull: Paul F – PersonEntity: Name: NameFull: Asgari N IsPartOfRelationships: – BibEntity: Dates: – D: 16 M: 07 Text: 2026 Jul 16 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 2193-8253 Titles: – TitleFull: Neurology and therapy Type: main |
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