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OTU deubiquitinases as immune-circuit editors: from human immunopathology to therapeutic prioritization.

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Title: OTU deubiquitinases as immune-circuit editors: from human immunopathology to therapeutic prioritization.
Authors: Guo Y; School of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, Xianning, China.; Hubei Key Laboratory of Environmental Risks and Related Diseases Precision Control, Hubei University of Science and Technology, Xianning, China., Song Y; School of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, Xianning, China., Wang C; School of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, Xianning, China., Xiong R; School of Health Management, Xianning Vocational Technical College, Xianning, China., Bao X; School of Public Health and Nursing, Hubei University of Science and Technology, Xianning, China., Lu S; School of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, Xianning, China., Wu W; School of Stomatology and Ophthalmology, Xianning Medical College, Hubei University of Science and Technology, Xianning, China., Wang X; School of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, Xianning, China., Liao J; School of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, Xianning, China., Bao Y; School of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, Xianning, China., Qu L; School of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, Xianning, China.; Hubei Key Laboratory of Environmental Risks and Related Diseases Precision Control, Hubei University of Science and Technology, Xianning, China., Rao Z; Department of Pharmacy, Xianning Central Hospital, The First Affiliated Hospital of Hubei University of Science and Technology, Xianning, China., Han Q; Department of Oncology, Xianning Central Hospital, The First Affiliated Hospital of Hubei University of Science and Technology, Xianning, China.
Source: Frontiers in immunology [Front Immunol] 2026 Jul 01; Vol. 17, pp. 1843621. Date of Electronic Publication: 2026 Jul 01 (Print Publication: 2026).
Publication Type: Journal Article; Review
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Guo+Y%22">Guo Y</searchLink>; School of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, Xianning, China.; Hubei Key Laboratory of Environmental Risks and Related Diseases Precision Control, Hubei University of Science and Technology, Xianning, China.<br /><searchLink fieldCode="AU" term="%22Song+Y%22">Song Y</searchLink>; School of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, Xianning, China.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; School of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, Xianning, China.<br /><searchLink fieldCode="AU" term="%22Xiong+R%22">Xiong R</searchLink>; School of Health Management, Xianning Vocational Technical College, Xianning, China.<br /><searchLink fieldCode="AU" term="%22Bao+X%22">Bao X</searchLink>; School of Public Health and Nursing, Hubei University of Science and Technology, Xianning, China.<br /><searchLink fieldCode="AU" term="%22Lu+S%22">Lu S</searchLink>; School of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, Xianning, China.<br /><searchLink fieldCode="AU" term="%22Wu+W%22">Wu W</searchLink>; School of Stomatology and Ophthalmology, Xianning Medical College, Hubei University of Science and Technology, Xianning, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; School of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, Xianning, China.<br /><searchLink fieldCode="AU" term="%22Liao+J%22">Liao J</searchLink>; School of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, Xianning, China.<br /><searchLink fieldCode="AU" term="%22Bao+Y%22">Bao Y</searchLink>; School of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, Xianning, China.<br /><searchLink fieldCode="AU" term="%22Qu+L%22">Qu L</searchLink>; School of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, Xianning, China.; Hubei Key Laboratory of Environmental Risks and Related Diseases Precision Control, Hubei University of Science and Technology, Xianning, China.<br /><searchLink fieldCode="AU" term="%22Rao+Z%22">Rao Z</searchLink>; Department of Pharmacy, Xianning Central Hospital, The First Affiliated Hospital of Hubei University of Science and Technology, Xianning, China.<br /><searchLink fieldCode="AU" term="%22Han+Q%22">Han Q</searchLink>; Department of Oncology, Xianning Central Hospital, The First Affiliated Hospital of Hubei University of Science and Technology, Xianning, China.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jul 01; Vol. 17, pp. 1843621. <i>Date of Electronic Publication: </i>2026 Jul 01 (<i>Print Publication: </i>2026).
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