Development and analysis of a SmPC-based machine-readable dataset of contraindications for clinical decision support and real-world data analysis.
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| Title: | Development and analysis of a SmPC-based machine-readable dataset of contraindications for clinical decision support and real-world data analysis. |
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| Authors: | Schechner M; Institute of General Practice and Family Medicine, LMU University Hospital, LMU Munich, Munich, Germany., Andrikyan W; Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Universitätsklinikum Erlangen, Erlangen, Germany., Bauerdick T; Department of Clinical Pharmacy, Institute of Pharmacy, University of Bonn, Bonn, Germany., Terstegen T; Medical Faculty Heidelberg, Internal Medicine IX, Clinical Pharmacology and Pharmacoepidemiology, Cooperation Unit Clinical Pharmacy, Heidelberg University, Heidelberg University Hospital, Heidelberg, Germany., Redeker L; Department of Clinical Pharmacology, School of Medicine, Faculty of Health, Witten / Herdecke University, Wuppertal, Germany., Federbusch M; Department for Clinical AI and Translational Medicine, University of Leipzig Medical Center, Leipzig, Germany.; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig Medical Center, Leipzig, Germany., Farker K; Institute for Hospital Pharmacy, University Center for Pharmacotherapy and Pharmacoeconomics, Jena University Hospital, Jena, Germany., Strübing A; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Leipzig University, Leipzig, Germany., Schmidt F; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Leipzig University, Leipzig, Germany., Thürmann P; Department of Clinical Pharmacology, School of Medicine, Faculty of Health, Witten / Herdecke University, Wuppertal, Germany., Schmiedl S; Department of Clinical Pharmacology, School of Medicine, Faculty of Health, Witten / Herdecke University, Wuppertal, Germany., Seidling HM; Medical Faculty Heidelberg, Internal Medicine IX, Clinical Pharmacology and Pharmacoepidemiology, Cooperation Unit Clinical Pharmacy, Heidelberg University, Heidelberg University Hospital, Heidelberg, Germany., Dreischulte T; Institute of General Practice and Family Medicine, LMU University Hospital, LMU Munich, Munich, Germany., Neumann D; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Leipzig University, Leipzig, Germany., Loeffler M; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Leipzig University, Leipzig, Germany., Maas R; Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; FAU NeW - Research Center New Bioactive Compounds, Friedrich- Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Jaehde U; Department of Clinical Pharmacy, Institute of Pharmacy, University of Bonn, Bonn, Germany., Fromm MF; Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; FAU NeW - Research Center New Bioactive Compounds, Friedrich- Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Sponfeldner MI; Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany. michael.sponfeldner@fau.de. |
| Corporate Authors: | INTERPOLAR project of the German Medical Informatics Initiative |
| Source: | European journal of clinical pharmacology [Eur J Clin Pharmacol] 2026 Jul 16; Vol. 82 (8). Date of Electronic Publication: 2026 Jul 16. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: Germany NLM ID: 1256165 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1041 (Electronic) Linking ISSN: 00316970 NLM ISO Abbreviation: Eur J Clin Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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