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Growth of PIK3CA-driven cerebral cavernous malformations does not require microbiome stimulation.

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Title: Growth of PIK3CA-driven cerebral cavernous malformations does not require microbiome stimulation.
Authors: Li L; Cardiovascular Institute and Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, United States of America., Lightle R; Section of Neurovascular Surgery Department of Neurological Surgery, The University of Chicago Medicine and Biological Sciences, Chicago, United States of America., Ali B; Section of Neurovascular Surgery Department of Neurological Surgery, The University of Chicago Medicine and Biological Sciences, Chicago, United States of America., Sader G; Section of Neurovascular Surgery Department of Neurological Surgery, The University of Chicago Medicine and Biological Sciences, Chicago, United States of America., Shenkar R; Section of Neurovascular Surgery Department of Neurological Surgery, The University of Chicago Medicine and Biological Sciences, Chicago, United States of America., Polster SP; Section of Neurovascular Surgery Department of Neurological Surgery, The University of Chicago Medicine and Biological Sciences, Chicago, United States of America., Marchuk DA; Departyment of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, United States of America., Burkhardt JK; Department of Neurosurgery, University of Pennsylvania, Perelman School of Medicine, Philadelphia, United States of America., Awad IA; Section of Neurovascular Surgery Department of Neurological Surgery, The University of Chicago Medicine and Biological Sciences, Chicago, United States of America., Kahn ML; Cardiovascular Institute and Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, United States of America.
Source: JCI insight [JCI Insight] 2026 Jul 16. Date of Electronic Publication: 2026 Jul 16.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Growth of PIK3CA-driven cerebral cavernous malformations does not require microbiome stimulation.
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  Data: <searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Cardiovascular Institute and Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, United States of America.<br /><searchLink fieldCode="AU" term="%22Lightle+R%22">Lightle R</searchLink>; Section of Neurovascular Surgery Department of Neurological Surgery, The University of Chicago Medicine and Biological Sciences, Chicago, United States of America.<br /><searchLink fieldCode="AU" term="%22Ali+B%22">Ali B</searchLink>; Section of Neurovascular Surgery Department of Neurological Surgery, The University of Chicago Medicine and Biological Sciences, Chicago, United States of America.<br /><searchLink fieldCode="AU" term="%22Sader+G%22">Sader G</searchLink>; Section of Neurovascular Surgery Department of Neurological Surgery, The University of Chicago Medicine and Biological Sciences, Chicago, United States of America.<br /><searchLink fieldCode="AU" term="%22Shenkar+R%22">Shenkar R</searchLink>; Section of Neurovascular Surgery Department of Neurological Surgery, The University of Chicago Medicine and Biological Sciences, Chicago, United States of America.<br /><searchLink fieldCode="AU" term="%22Polster+SP%22">Polster SP</searchLink>; Section of Neurovascular Surgery Department of Neurological Surgery, The University of Chicago Medicine and Biological Sciences, Chicago, United States of America.<br /><searchLink fieldCode="AU" term="%22Marchuk+DA%22">Marchuk DA</searchLink>; Departyment of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, United States of America.<br /><searchLink fieldCode="AU" term="%22Burkhardt+JK%22">Burkhardt JK</searchLink>; Department of Neurosurgery, University of Pennsylvania, Perelman School of Medicine, Philadelphia, United States of America.<br /><searchLink fieldCode="AU" term="%22Awad+IA%22">Awad IA</searchLink>; Section of Neurovascular Surgery Department of Neurological Surgery, The University of Chicago Medicine and Biological Sciences, Chicago, United States of America.<br /><searchLink fieldCode="AU" term="%22Kahn+ML%22">Kahn ML</searchLink>; Cardiovascular Institute and Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, United States of America.
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  Data: <searchLink fieldCode="JN" term="%22101676073%22">JCI insight</searchLink> [JCI Insight] 2026 Jul 16. <i>Date of Electronic Publication: </i>2026 Jul 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Clinical+Investigation%22">American Society for Clinical Investigation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101676073 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2379-3708 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223793708%22">23793708 </searchLink><i>NLM ISO Abbreviation: </i>JCI Insight <i>Subsets: </i>MEDLINE
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        Value: 10.1172/jci.insight.208733
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      – Code: eng
        Text: English
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      – TitleFull: Growth of PIK3CA-driven cerebral cavernous malformations does not require microbiome stimulation.
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              Text: 2026 Jul 16
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              Y: 2026
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