Study protocol of the C-SOLVE (JACCRO GC-12) trial; a randomized, non-comparative phase II trial of CapeOX or SOX plus zolbetuximab in HER2-negative, CLDN18.2-positive unresectable advanced gastric or esophagogastric junction cancer.
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| Title: | Study protocol of the C-SOLVE (JACCRO GC-12) trial; a randomized, non-comparative phase II trial of CapeOX or SOX plus zolbetuximab in HER2-negative, CLDN18.2-positive unresectable advanced gastric or esophagogastric junction cancer. |
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| Authors: | Yuki S; Department of Cancer Genomics and Precision Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Kawakami H; Department of Clinical Oncology, Tohoku University Graduate School of Medicine, 4-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575, Miyagi, Japan. kawakami_h@tohoku.ac.jp., Harada K; Divison of Cancer Center, Hokkaido University Hospital, Sapporo, Japan., Kubota Y; Department of Clinical Oncology, St. Marianna University School of Medicine, Kawasaki, Japan., Pak K; Division of Biostatistics, Department of Data Management, Center for Clinical Research, National Center for Child Health and Development, Tokyo, Japan., Kakeji Y; Division of Gastro-intestinal Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan., Terashima M; Division of Gastric Surgery, Shizuoka Cancer Center, Shizuoka, Japan., Baba E; Department of Comprehensive Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Muro K; Department of Clinical Oncology, Aichi Cancer Center Hospital, Nagoya, Japan., Sunakawa Y; Department of Clinical Oncology, St. Marianna University School of Medicine, Kawasaki, Japan., Ichikawa W; Department of Medical Oncology, Sonoda Daiichi Hospital, Tokyo, Japan., Fujii M; Japan Clinical Cancer Research Organization (JACCRO), Tokyo, Japan. |
| Source: | BMC cancer [BMC Cancer] 2026 Jul 17. Date of Electronic Publication: 2026 Jul 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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