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ICAM-1⁺CD51⁺ CAFs drive immunosuppression in colorectal cancer via OPN-triggered chemokine secretion.

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Title: ICAM-1⁺CD51⁺ CAFs drive immunosuppression in colorectal cancer via OPN-triggered chemokine secretion.
Authors: Liu J; Department of Pathology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou Medical University, Xuzhou, 221004, China., Xue S; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, 221004, China., Xu Y; Department of General Surgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.; Institute of Digestive Diseases, Xuzhou Medical University, Xuzhou, Jiangsu, China., Wu S; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, 221004, China., Zhao W; Laboratory of Clinical and Experimental Pathology, Department of Pathology, Xuzhou Medical University, Xuzhou, Jiangsu, China., Li X; Laboratory of Clinical and Experimental Pathology, Department of Pathology, Xuzhou Medical University, Xuzhou, Jiangsu, China., Hu N; Laboratory of Clinical and Experimental Pathology, Department of Pathology, Xuzhou Medical University, Xuzhou, Jiangsu, China., Sun J; Laboratory of Clinical and Experimental Pathology, Department of Pathology, Xuzhou Medical University, Xuzhou, Jiangsu, China. sunjinmin09@xzhmu.edu.cn., Ren J; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, 221004, China. renjing@xzhmu.edu.cn.
Source: Journal of translational medicine [J Transl Med] 2026 Jul 17; Vol. 24 (1). Date of Electronic Publication: 2026 Jul 17.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: ICAM-1⁺CD51⁺ CAFs drive immunosuppression in colorectal cancer via OPN-triggered chemokine secretion.
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  Data: <searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Department of Pathology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou Medical University, Xuzhou, 221004, China.<br /><searchLink fieldCode="AU" term="%22Xue+S%22">Xue S</searchLink>; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, 221004, China.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Department of General Surgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.; Institute of Digestive Diseases, Xuzhou Medical University, Xuzhou, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Wu+S%22">Wu S</searchLink>; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, 221004, China.<br /><searchLink fieldCode="AU" term="%22Zhao+W%22">Zhao W</searchLink>; Laboratory of Clinical and Experimental Pathology, Department of Pathology, Xuzhou Medical University, Xuzhou, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Laboratory of Clinical and Experimental Pathology, Department of Pathology, Xuzhou Medical University, Xuzhou, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Hu+N%22">Hu N</searchLink>; Laboratory of Clinical and Experimental Pathology, Department of Pathology, Xuzhou Medical University, Xuzhou, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Sun+J%22">Sun J</searchLink>; Laboratory of Clinical and Experimental Pathology, Department of Pathology, Xuzhou Medical University, Xuzhou, Jiangsu, China. sunjinmin09@xzhmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Ren+J%22">Ren J</searchLink>; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, 221004, China. renjing@xzhmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101190741%22">Journal of translational medicine</searchLink> [J Transl Med] 2026 Jul 17; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 Jul 17.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101190741 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1479-5876 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214795876%22">14795876 </searchLink><i>NLM ISO Abbreviation: </i>J Transl Med <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12967-026-08642-9
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      – Code: eng
        Text: English
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      – TitleFull: ICAM-1⁺CD51⁺ CAFs drive immunosuppression in colorectal cancer via OPN-triggered chemokine secretion.
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              Text: 2026 Jul 17
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              Y: 2026
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