Baseline and placebo-related imaging, cerebrospinal fluid, plasma biomarker, and cognitive findings in unimpaired PSEN1 E280A mutation carriers and non-carriers in the Alzheimer's Prevention Initiative Autosomal Dominant Alzheimer's Disease Colombia Trial.

Saved in:
Bibliographic Details
Title: Baseline and placebo-related imaging, cerebrospinal fluid, plasma biomarker, and cognitive findings in unimpaired PSEN1 E280A mutation carriers and non-carriers in the Alzheimer's Prevention Initiative Autosomal Dominant Alzheimer's Disease Colombia Trial.
Authors: Bittner T; Genentech, Inc., South San Francisco, CA, USA; F. Hoffmann-La Roche Ltd, Basel, Switzerland., Lopera F; Neuroscience Group of Antioquia, University of Antioquia, Medellín, Colombia., Rios-Romenets S; Neuroscience Group of Antioquia, University of Antioquia, Medellín, Colombia., Schiffman C; Genentech, Inc., South San Francisco, CA, USA., Clayton D; Genentech, Inc., South San Francisco, CA, USA., Hibar D; Genentech, Inc., South San Francisco, CA, USA., Kollmorgen G; Roche Diagnostics, Penzberg, Germany., Dolton M; Genentech, Inc., South San Francisco, CA, USA., Poon V; Genentech, Inc., South San Francisco, CA, USA., Nguyen J; Genentech, Inc., South San Francisco, CA, USA., Giraldo-Chica M; Neuroscience Group of Antioquia, University of Antioquia, Medellín, Colombia., Acosta-Baena N; Neuroscience Group of Antioquia, University of Antioquia, Medellín, Colombia., Espinosa A; Neuroscience Group of Antioquia, University of Antioquia, Medellín, Colombia; Hospital San Juan de Dios de Yarumal, Antioquia, Colombia., Villegas G; Neuroscience Group of Antioquia, University of Antioquia, Medellín, Colombia., Muñoz C; Neuroscience Group of Antioquia, University of Antioquia, Medellín, Colombia., Serna L; Neuroscience Group of Antioquia, University of Antioquia, Medellín, Colombia., Alvarez S; Hospital Pablo Tobón Uribe, Medellín, Colombia., Protas H; Banner Alzheimer's Institute, Phoenix, AZ, USA., Luo J; Banner Alzheimer's Institute, Phoenix, AZ, USA., Sohankar J; Banner Alzheimer's Institute, Phoenix, AZ, USA., Chen Y; Banner Alzheimer's Institute, Phoenix, AZ, USA., Ghisays V; Banner Alzheimer's Institute, Phoenix, AZ, USA., Malek-Ahmadi M; Banner Alzheimer's Institute, Phoenix, AZ, USA., Ashton NJ; Banner Alzheimer's Institute, Phoenix, AZ, USA; Banner Sun Health Research Institute, Sun City, AZ, USA; Department of Psychiatry and Neurochemistry, Institute of Neuroscience & Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden., Denkinger MN; Banner Sun Health Research Institute, Sun City, AZ, USA., Cai Y; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Xu YR; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Ostaszewski B; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Selkoe DJ; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Alexander RC; Banner Alzheimer's Institute, Phoenix, AZ, USA., Quiroz YT; Departments of Psychiatry and Neurology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA., Su Y; Banner Alzheimer's Institute, Phoenix, AZ, USA., Chen K; Banner Alzheimer's Institute, Phoenix, AZ, USA., Doody RS; Genentech, Inc., South San Francisco, CA, USA; F. Hoffmann-La Roche Ltd, Basel, Switzerland., Langbaum JB; Banner Alzheimer's Institute, Phoenix, AZ, USA., Tariot PN; Banner Alzheimer's Institute, Phoenix, AZ, USA., Sink KM; Genentech, Inc., South San Francisco, CA, USA., Reiman EM; Banner Alzheimer's Institute, Phoenix, AZ, USA. Electronic address: Eric.Reiman@bannerhealth.com.
Source: EBioMedicine [EBioMedicine] 2026 Jul 17; Vol. 130, pp. 106390. Date of Electronic Publication: 2026 Jul 17.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2352-3964
DOI:10.1016/j.ebiom.2026.106390