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Multi-centre generalisability of deep learning-based dose prediction for head and neck radiotherapy using DAHANCA real-world data.

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Title: Multi-centre generalisability of deep learning-based dose prediction for head and neck radiotherapy using DAHANCA real-world data.
Authors: Nielsen CP; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark; Institute of Clinical Research, University of Southern Denmark, Denmark. Electronic address: camilla.panduro.nielsen@rsyd.dk., Huet-Dastarac M; Molecular Imaging, Radiotherapy and Oncology, Institut de Recherche Expérimentale et Clinique, UCLouvain, Belgium., Jensen K; Danish Centre for Particle Therapy, Aarhus University Hospital, Denmark., Brink C; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark; Institute of Clinical Research, University of Southern Denmark, Denmark., Smulders B; Danish Centre for Particle Therapy, Aarhus University Hospital, Denmark; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Denmark., Holm AIS; Department of Oncology, Aarhus University Hospital, Denmark., Nielsen MS; Department of Oncology, Aalborg University Hospital, Aalborg, Denmark., Sibolt P; Department of Oncology, Copenhagen University Hospital - Herlev & Gentofte, Denmark., Lee JA; Molecular Imaging, Radiotherapy and Oncology, Institut de Recherche Expérimentale et Clinique, UCLouvain, Belgium., Sterpin E; Molecular Imaging, Radiotherapy and Oncology, Institut de Recherche Expérimentale et Clinique, UCLouvain, Belgium; Department of Oncology, Laboratory of Experimental Radiotherapy, KU Leuven, Belgium., Zukauskaite R; Department of Oncology, Odense University Hospital, Denmark., Johansen J; Institute of Clinical Research, University of Southern Denmark, Denmark; Department of Oncology, Odense University Hospital, Denmark., Krogh SL; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark., Konrad ML; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark; Institute of Clinical Research, University of Southern Denmark, Denmark., Friborg J; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Denmark., Sommer JFA; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark., Stougaard SW; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark; Institute of Clinical Research, University of Southern Denmark, Denmark., Overgaard J; Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark., Toustrup K; Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark., Lonkvist CK; Department of Oncology, Copenhagen University Hospital - Herlev & Gentofte, Denmark., Farhadi M; Department of Oncology and Palliative Care, Zealand University Hospital, Næstved, Denmark., Kaplan LP; Department of Oncology and Palliative Care, Zealand University Hospital, Næstved, Denmark., Kjeldsen R; Department of Oncology, Aalborg University Hospital, Aalborg, Denmark., Lorenzen EL; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark; Institute of Clinical Research, University of Southern Denmark, Denmark., Barragán-Montero AM; Molecular Imaging, Radiotherapy and Oncology, Institut de Recherche Expérimentale et Clinique, UCLouvain, Belgium., Hansen CR; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark; Institute of Clinical Research, University of Southern Denmark, Denmark; Danish Centre for Particle Therapy, Aarhus University Hospital, Denmark.
Source: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2026 Jul 17; Vol. 222, pp. 111702. Date of Electronic Publication: 2026 Jul 17.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8407192 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0887 (Electronic) Linking ISSN: 01678140 NLM ISO Abbreviation: Radiother Oncol Subsets: MEDLINE
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  Data: Multi-centre generalisability of deep learning-based dose prediction for head and neck radiotherapy using DAHANCA real-world data.
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  Data: <searchLink fieldCode="AU" term="%22Nielsen+CP%22">Nielsen CP</searchLink>; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark; Institute of Clinical Research, University of Southern Denmark, Denmark. Electronic address: camilla.panduro.nielsen@rsyd.dk.<br /><searchLink fieldCode="AU" term="%22Huet-Dastarac+M%22">Huet-Dastarac M</searchLink>; Molecular Imaging, Radiotherapy and Oncology, Institut de Recherche Expérimentale et Clinique, UCLouvain, Belgium.<br /><searchLink fieldCode="AU" term="%22Jensen+K%22">Jensen K</searchLink>; Danish Centre for Particle Therapy, Aarhus University Hospital, Denmark.<br /><searchLink fieldCode="AU" term="%22Brink+C%22">Brink C</searchLink>; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark; Institute of Clinical Research, University of Southern Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Smulders+B%22">Smulders B</searchLink>; Danish Centre for Particle Therapy, Aarhus University Hospital, Denmark; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Denmark.<br /><searchLink fieldCode="AU" term="%22Holm+AIS%22">Holm AIS</searchLink>; Department of Oncology, Aarhus University Hospital, Denmark.<br /><searchLink fieldCode="AU" term="%22Nielsen+MS%22">Nielsen MS</searchLink>; Department of Oncology, Aalborg University Hospital, Aalborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Sibolt+P%22">Sibolt P</searchLink>; Department of Oncology, Copenhagen University Hospital - Herlev & Gentofte, Denmark.<br /><searchLink fieldCode="AU" term="%22Lee+JA%22">Lee JA</searchLink>; Molecular Imaging, Radiotherapy and Oncology, Institut de Recherche Expérimentale et Clinique, UCLouvain, Belgium.<br /><searchLink fieldCode="AU" term="%22Sterpin+E%22">Sterpin E</searchLink>; Molecular Imaging, Radiotherapy and Oncology, Institut de Recherche Expérimentale et Clinique, UCLouvain, Belgium; Department of Oncology, Laboratory of Experimental Radiotherapy, KU Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Zukauskaite+R%22">Zukauskaite R</searchLink>; Department of Oncology, Odense University Hospital, Denmark.<br /><searchLink fieldCode="AU" term="%22Johansen+J%22">Johansen J</searchLink>; Institute of Clinical Research, University of Southern Denmark, Denmark; Department of Oncology, Odense University Hospital, Denmark.<br /><searchLink fieldCode="AU" term="%22Krogh+SL%22">Krogh SL</searchLink>; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark.<br /><searchLink fieldCode="AU" term="%22Konrad+ML%22">Konrad ML</searchLink>; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark; Institute of Clinical Research, University of Southern Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Friborg+J%22">Friborg J</searchLink>; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Denmark.<br /><searchLink fieldCode="AU" term="%22Sommer+JFA%22">Sommer JFA</searchLink>; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark.<br /><searchLink fieldCode="AU" term="%22Stougaard+SW%22">Stougaard SW</searchLink>; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark; Institute of Clinical Research, University of Southern Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Overgaard+J%22">Overgaard J</searchLink>; Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark.<br /><searchLink fieldCode="AU" term="%22Toustrup+K%22">Toustrup K</searchLink>; Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark.<br /><searchLink fieldCode="AU" term="%22Lonkvist+CK%22">Lonkvist CK</searchLink>; Department of Oncology, Copenhagen University Hospital - Herlev & Gentofte, Denmark.<br /><searchLink fieldCode="AU" term="%22Farhadi+M%22">Farhadi M</searchLink>; Department of Oncology and Palliative Care, Zealand University Hospital, Næstved, Denmark.<br /><searchLink fieldCode="AU" term="%22Kaplan+LP%22">Kaplan LP</searchLink>; Department of Oncology and Palliative Care, Zealand University Hospital, Næstved, Denmark.<br /><searchLink fieldCode="AU" term="%22Kjeldsen+R%22">Kjeldsen R</searchLink>; Department of Oncology, Aalborg University Hospital, Aalborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Lorenzen+EL%22">Lorenzen EL</searchLink>; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark; Institute of Clinical Research, University of Southern Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Barragán-Montero+AM%22">Barragán-Montero AM</searchLink>; Molecular Imaging, Radiotherapy and Oncology, Institut de Recherche Expérimentale et Clinique, UCLouvain, Belgium.<br /><searchLink fieldCode="AU" term="%22Hansen+CR%22">Hansen CR</searchLink>; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark; Institute of Clinical Research, University of Southern Denmark, Denmark; Danish Centre for Particle Therapy, Aarhus University Hospital, Denmark.
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