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Daphnoretin as a multifunctional natural biscoumarin: Chemistry, biological activities, and mechanistic insights.

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Title: Daphnoretin as a multifunctional natural biscoumarin: Chemistry, biological activities, and mechanistic insights.
Authors: Ibrahim SRM; Department of Chemistry, Preparatory Year Program, Batterjee Medical College, Jeddah 21442, Saudi Arabia; Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt. Electronic address: sabrin.ibrahim@bmc.edu.sa., Mohamed HM; Department of Medical Laboratory Analysis, College of Medical & Health Sciences, Liwa University, Abu Dhabi 41009, United Arab Emirates; Department of Applied Medical Chemistry, Medical Research Institute, Alexandria University, Alexandria, Egypt. Electronic address: Hagar.aly@lc.ac.ae., Ibrahim A; Fsgene Biotec Company, 9550, Al Mutamid Bin Ibad 3925, Al Manarat Dist, Jeddah 23829, Saudi Arabia., Fayed MAA; Department of Pharmacognosy, Faculty of Pharmacy, University of Sadat City, Sadat City 32897, Egypt. Electronic address: marwa.fayed@fop.usc.edu.eg., Elseragy MA; Department of Pharmacognosy, Faculty of Pharmacy, University of Sadat City, Sadat City 32897, Egypt. Electronic address: merna.elseragy@fop.usc.edu.eg., Abdallah HM; Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia; Department of Pharmacognosy, College of Pharmacy, Cairo University, Kasr El-Aini St., Cairo 11562, Egypt. Electronic address: hmafifi@kau.edu.sa., Elamin KM; Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan. Electronic address: Khaled@kumamoto-u.ac.jp., Mohamed GA; Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia. Electronic address: gahussein@kau.edu.sa.
Source: Fitoterapia [Fitoterapia] 2026 Jul 17; Vol. 193, pp. 107396. Date of Electronic Publication: 2026 Jul 17.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE
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  Data: Daphnoretin as a multifunctional natural biscoumarin: Chemistry, biological activities, and mechanistic insights.
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  Data: <searchLink fieldCode="AU" term="%22Ibrahim+SRM%22">Ibrahim SRM</searchLink>; Department of Chemistry, Preparatory Year Program, Batterjee Medical College, Jeddah 21442, Saudi Arabia; Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt. Electronic address: sabrin.ibrahim@bmc.edu.sa.<br /><searchLink fieldCode="AU" term="%22Mohamed+HM%22">Mohamed HM</searchLink>; Department of Medical Laboratory Analysis, College of Medical & Health Sciences, Liwa University, Abu Dhabi 41009, United Arab Emirates; Department of Applied Medical Chemistry, Medical Research Institute, Alexandria University, Alexandria, Egypt. Electronic address: Hagar.aly@lc.ac.ae.<br /><searchLink fieldCode="AU" term="%22Ibrahim+A%22">Ibrahim A</searchLink>; Fsgene Biotec Company, 9550, Al Mutamid Bin Ibad 3925, Al Manarat Dist, Jeddah 23829, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Fayed+MAA%22">Fayed MAA</searchLink>; Department of Pharmacognosy, Faculty of Pharmacy, University of Sadat City, Sadat City 32897, Egypt. Electronic address: marwa.fayed@fop.usc.edu.eg.<br /><searchLink fieldCode="AU" term="%22Elseragy+MA%22">Elseragy MA</searchLink>; Department of Pharmacognosy, Faculty of Pharmacy, University of Sadat City, Sadat City 32897, Egypt. Electronic address: merna.elseragy@fop.usc.edu.eg.<br /><searchLink fieldCode="AU" term="%22Abdallah+HM%22">Abdallah HM</searchLink>; Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia; Department of Pharmacognosy, College of Pharmacy, Cairo University, Kasr El-Aini St., Cairo 11562, Egypt. Electronic address: hmafifi@kau.edu.sa.<br /><searchLink fieldCode="AU" term="%22Elamin+KM%22">Elamin KM</searchLink>; Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan. Electronic address: Khaled@kumamoto-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Mohamed+GA%22">Mohamed GA</searchLink>; Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia. Electronic address: gahussein@kau.edu.sa.
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  Data: <searchLink fieldCode="JN" term="%2216930290R%22">Fitoterapia</searchLink> [Fitoterapia] 2026 Jul 17; Vol. 193, pp. 107396. <i>Date of Electronic Publication: </i>2026 Jul 17.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>16930290R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-6971 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220367326X%22">0367326X </searchLink><i>NLM ISO Abbreviation: </i>Fitoterapia <i>Subsets: </i>MEDLINE
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              Text: 2026 Jul 17
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