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Development and external validation of AI-ECG models in athlete pre-participation screening: Performance, limitations, and clinical implications.

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Title: Development and external validation of AI-ECG models in athlete pre-participation screening: Performance, limitations, and clinical implications.
Authors: Palermi S; Department of Medicine and Surgery, UniCamillus-Saint Camillus International University of Health Sciences, Rome, Italy. Electronic address: stefano.palermi@unicamillus.org., Zeidaabadi B; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: boroumand.zeidaabadi20@imperial.ac.uk., Vecchiato M; Sports and Exercise Medicine Division, Department of Medicine, University of Padova, Padova, Italy; Department of Theoretical and Applied Sciences, eCampus University, Novedrate, Como, Italy., Anselmino M; Division of Cardiology, Cardiovascular and Thoracic Department, Città della Salute e della Scienza, Turin, Italy; Department of Medical Sciences, University of Turin, Turin, Italy. Electronic address: matteo.anselmino@unito.it., Adorisio R; Bambino Gesù Children's Hospital, IRCCS, Rome, Italy. Electronic address: rachele.adorisio@opbg.net., Biffi A; Med-Ex, Medicine & Exercise, Medical Partner Scuderia Ferrari, Rome, Italy., Borrelli F; Sports Medicine Institute, Turin, Italy., Brugin E; Sports and Exercise Medicine Division, Department of Medical Specialties, ULSS 3 Serenissima, Noale, Venice, Italy. Electronic address: erica.brugin@aulss3.veneto.it., Cantarutti N; Bambino Gesù Children's Hospital, IRCCS, Rome, Italy. Electronic address: nicoletta.cantarutti@opbg.net., Cavarretta E; Bambino Gesù Children's Hospital, IRCCS, Rome, Italy; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy. Electronic address: elena.cavarretta@uniroma1.it., Cominacini M; University of Verona, Verona, Italy. Electronic address: mattia.cominacini@univr.it., Corsi M; Sports Medicine Center, University of Florence, Florence, Italy. Electronic address: marco.corsi@unifi.it., DAscenzi F; Department of Medical Biotechnologies, Sports Cardiology and Rehab Unit, University of Siena, Siena, Italy. Electronic address: dascenzi2@unisi.it., De Feo V; M.d.S. srl, Pescara, Italy; University Cardiology Division, SS Annunziata Polyclinic University Hospital, Chieti, Italy. Electronic address: info@mdspescara.it., Di Gioia G; Institute of Sport Medicine and Science, Italian National Olympic Committee, Largo Piero Gabrielli, Rome, Italy., Dorelli G; University of Verona, Verona, Italy. Electronic address: gianluigi.dorelli@univr.it., Foccardi G; Sports and Exercise Medicine Division, Department of Medical Specialties, ULSS 3 Serenissima, Noale, Venice, Italy., Gallina S; University Cardiology Division, SS Annunziata Polyclinic University Hospital, Chieti, Italy. Electronic address: sabina.gallina@unich.it., Giangrandi S; Department of Medical Biotechnologies, Sports Cardiology and Rehab Unit, University of Siena, Siena, Italy., Graziano F; Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy. Electronic address: francesca.graziano@unipd.it., Aggour H; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: h.aggour@imperial.ac.uk., El-Medany A; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: a.el-medany24@imperial.ac.uk., Pastika L; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: libor.myslivecek21@imperial.ac.uk., Barker J; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: joseph.barker07@imperial.ac.uk., Patlatzoglou K; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: k.patlatzoglou@imperial.ac.uk., Khattak GR; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: g.khattak@imperial.ac.uk., Lodi E; Centro PASCIA (Programma Assistenziale Scompenso cardiaco, Cardiopatie dell'Infanzia e A rischio), Modena, Italy. Electronic address: elisa.lodi@unimore.it., Livio A; Sports and Exercise Medicine Division, Department of Medicine, University of Padova, Padova, Italy. Electronic address: alberto.livio@studenti.unipd.it., Maestrini V; Institute of Sport Medicine and Science, Italian National Olympic Committee, Largo Piero Gabrielli, Rome, Italy. Electronic address: viviana.maestrini@uniroma1.it., Manfredi GL; Department of Medical Biotechnologies, Sports Cardiology and Rehab Unit, University of Siena, Siena, Italy., Mansour D; University Cardiology Division, SS Annunziata Polyclinic University Hospital, Chieti, Italy., Modena M; Centro PASCIA (Programma Assistenziale Scompenso cardiaco, Cardiopatie dell'Infanzia e A rischio), Modena, Italy. Electronic address: mariagrazia.modena@unimore.it., Neunhaeuserer D; Sports and Exercise Medicine Division, Department of Medicine, University of Padova, Padova, Italy. Electronic address: daniel.neunhaeuserer@unipd.it., Nigro A; Villa Stuart Sport Clinic, FIFA Medical Center of Excellence, via Trionfale 5952, Rome, Italy., Palermi A; University Cardiology Division, SS Annunziata Polyclinic University Hospital, Chieti, Italy., Pellegrino A; Sports Medicine Center, University of Florence, Florence, Italy. Electronic address: alessio.pellegrino@unifi.it., Pelliccia A; Institute of Sport Medicine and Science, Italian National Olympic Committee, Largo Piero Gabrielli, Rome, Italy., Quattrini FM; Health Promotion, Prevention Plans and Sports Medicine Unit, Department of Prevention, ASL Roma 2, Rome, Italy. Electronic address: filippomaria.quattrini@aslroma2.it., Ricci F; University Cardiology Division, SS Annunziata Polyclinic University Hospital, Chieti, Italy. Electronic address: fabrizio.ricci@unich.it., Scarzella F; Sports Medicine Institute, Turin, Italy. Electronic address: fiammetta.scarzella@imsto.it., Squeo MR; Institute of Sport Medicine and Science, Italian National Olympic Committee, Largo Piero Gabrielli, Rome, Italy. Electronic address: mariarosaria.squeo@coni.it., Tonelli R; Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy., Zanardo E; Sports and Exercise Medicine Division, Department of Medicine, University of Padova, Padova, Italy. Electronic address: Emanuele.zanardo@studenti.unipd.it., Zorzi A; Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy., Peters NS; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: n.peters@imperial.ac.uk., Kramer DB; Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. Electronic address: dkramer@bidmc.harvard.edu., Waks JW; Harvard-Thorndike Electrophysiology Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. Electronic address: jwaks@bidmc.harvard.edu., De Ferrari GM; Division of Cardiology, Cardiovascular and Thoracic Department, Città della Salute e della Scienza, Turin, Italy; Department of Medical Sciences, University of Turin, Turin, Italy. Electronic address: gaetano.deferrari@unito.it., Ng FS; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: f.ng@imperial.ac.uk., Sau A; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: arunashis.sau09@imperial.ac.uk., Saglietto A; Division of Cardiology, Cardiovascular and Thoracic Department, Città della Salute e della Scienza, Turin, Italy; Department of Medical Sciences, University of Turin, Turin, Italy.
Source: International journal of cardiology [Int J Cardiol] 2026 Jul 17; Vol. 461, pp. 134677. Date of Electronic Publication: 2026 Jul 17.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8200291 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1874-1754 (Electronic) Linking ISSN: 01675273 NLM ISO Abbreviation: Int J Cardiol Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42468692
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PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Label: Title
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  Data: Development and external validation of AI-ECG models in athlete pre-participation screening: Performance, limitations, and clinical implications.
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  Data: <searchLink fieldCode="AU" term="%22Palermi+S%22">Palermi S</searchLink>; Department of Medicine and Surgery, UniCamillus-Saint Camillus International University of Health Sciences, Rome, Italy. Electronic address: stefano.palermi@unicamillus.org.<br /><searchLink fieldCode="AU" term="%22Zeidaabadi+B%22">Zeidaabadi B</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: boroumand.zeidaabadi20@imperial.ac.uk.<br /><searchLink fieldCode="AU" term="%22Vecchiato+M%22">Vecchiato M</searchLink>; Sports and Exercise Medicine Division, Department of Medicine, University of Padova, Padova, Italy; Department of Theoretical and Applied Sciences, eCampus University, Novedrate, Como, Italy.<br /><searchLink fieldCode="AU" term="%22Anselmino+M%22">Anselmino M</searchLink>; Division of Cardiology, Cardiovascular and Thoracic Department, Città della Salute e della Scienza, Turin, Italy; Department of Medical Sciences, University of Turin, Turin, Italy. Electronic address: matteo.anselmino@unito.it.<br /><searchLink fieldCode="AU" term="%22Adorisio+R%22">Adorisio R</searchLink>; Bambino Gesù Children's Hospital, IRCCS, Rome, Italy. Electronic address: rachele.adorisio@opbg.net.<br /><searchLink fieldCode="AU" term="%22Biffi+A%22">Biffi A</searchLink>; Med-Ex, Medicine & Exercise, Medical Partner Scuderia Ferrari, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Borrelli+F%22">Borrelli F</searchLink>; Sports Medicine Institute, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Brugin+E%22">Brugin E</searchLink>; Sports and Exercise Medicine Division, Department of Medical Specialties, ULSS 3 Serenissima, Noale, Venice, Italy. Electronic address: erica.brugin@aulss3.veneto.it.<br /><searchLink fieldCode="AU" term="%22Cantarutti+N%22">Cantarutti N</searchLink>; Bambino Gesù Children's Hospital, IRCCS, Rome, Italy. Electronic address: nicoletta.cantarutti@opbg.net.<br /><searchLink fieldCode="AU" term="%22Cavarretta+E%22">Cavarretta E</searchLink>; Bambino Gesù Children's Hospital, IRCCS, Rome, Italy; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy. Electronic address: elena.cavarretta@uniroma1.it.<br /><searchLink fieldCode="AU" term="%22Cominacini+M%22">Cominacini M</searchLink>; University of Verona, Verona, Italy. Electronic address: mattia.cominacini@univr.it.<br /><searchLink fieldCode="AU" term="%22Corsi+M%22">Corsi M</searchLink>; Sports Medicine Center, University of Florence, Florence, Italy. Electronic address: marco.corsi@unifi.it.<br /><searchLink fieldCode="AU" term="%22DAscenzi+F%22">DAscenzi F</searchLink>; Department of Medical Biotechnologies, Sports Cardiology and Rehab Unit, University of Siena, Siena, Italy. Electronic address: dascenzi2@unisi.it.<br /><searchLink fieldCode="AU" term="%22De+Feo+V%22">De Feo V</searchLink>; M.d.S. srl, Pescara, Italy; University Cardiology Division, SS Annunziata Polyclinic University Hospital, Chieti, Italy. Electronic address: info@mdspescara.it.<br /><searchLink fieldCode="AU" term="%22Di+Gioia+G%22">Di Gioia G</searchLink>; Institute of Sport Medicine and Science, Italian National Olympic Committee, Largo Piero Gabrielli, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Dorelli+G%22">Dorelli G</searchLink>; University of Verona, Verona, Italy. Electronic address: gianluigi.dorelli@univr.it.<br /><searchLink fieldCode="AU" term="%22Foccardi+G%22">Foccardi G</searchLink>; Sports and Exercise Medicine Division, Department of Medical Specialties, ULSS 3 Serenissima, Noale, Venice, Italy.<br /><searchLink fieldCode="AU" term="%22Gallina+S%22">Gallina S</searchLink>; University Cardiology Division, SS Annunziata Polyclinic University Hospital, Chieti, Italy. Electronic address: sabina.gallina@unich.it.<br /><searchLink fieldCode="AU" term="%22Giangrandi+S%22">Giangrandi S</searchLink>; Department of Medical Biotechnologies, Sports Cardiology and Rehab Unit, University of Siena, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Graziano+F%22">Graziano F</searchLink>; Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy. Electronic address: francesca.graziano@unipd.it.<br /><searchLink fieldCode="AU" term="%22Aggour+H%22">Aggour H</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: h.aggour@imperial.ac.uk.<br /><searchLink fieldCode="AU" term="%22El-Medany+A%22">El-Medany A</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: a.el-medany24@imperial.ac.uk.<br /><searchLink fieldCode="AU" term="%22Pastika+L%22">Pastika L</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: libor.myslivecek21@imperial.ac.uk.<br /><searchLink fieldCode="AU" term="%22Barker+J%22">Barker J</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: joseph.barker07@imperial.ac.uk.<br /><searchLink fieldCode="AU" term="%22Patlatzoglou+K%22">Patlatzoglou K</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: k.patlatzoglou@imperial.ac.uk.<br /><searchLink fieldCode="AU" term="%22Khattak+GR%22">Khattak GR</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: g.khattak@imperial.ac.uk.<br /><searchLink fieldCode="AU" term="%22Lodi+E%22">Lodi E</searchLink>; Centro PASCIA (Programma Assistenziale Scompenso cardiaco, Cardiopatie dell'Infanzia e A rischio), Modena, Italy. Electronic address: elisa.lodi@unimore.it.<br /><searchLink fieldCode="AU" term="%22Livio+A%22">Livio A</searchLink>; Sports and Exercise Medicine Division, Department of Medicine, University of Padova, Padova, Italy. Electronic address: alberto.livio@studenti.unipd.it.<br /><searchLink fieldCode="AU" term="%22Maestrini+V%22">Maestrini V</searchLink>; Institute of Sport Medicine and Science, Italian National Olympic Committee, Largo Piero Gabrielli, Rome, Italy. Electronic address: viviana.maestrini@uniroma1.it.<br /><searchLink fieldCode="AU" term="%22Manfredi+GL%22">Manfredi GL</searchLink>; Department of Medical Biotechnologies, Sports Cardiology and Rehab Unit, University of Siena, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Mansour+D%22">Mansour D</searchLink>; University Cardiology Division, SS Annunziata Polyclinic University Hospital, Chieti, Italy.<br /><searchLink fieldCode="AU" term="%22Modena+M%22">Modena M</searchLink>; Centro PASCIA (Programma Assistenziale Scompenso cardiaco, Cardiopatie dell'Infanzia e A rischio), Modena, Italy. Electronic address: mariagrazia.modena@unimore.it.<br /><searchLink fieldCode="AU" term="%22Neunhaeuserer+D%22">Neunhaeuserer D</searchLink>; Sports and Exercise Medicine Division, Department of Medicine, University of Padova, Padova, Italy. Electronic address: daniel.neunhaeuserer@unipd.it.<br /><searchLink fieldCode="AU" term="%22Nigro+A%22">Nigro A</searchLink>; Villa Stuart Sport Clinic, FIFA Medical Center of Excellence, via Trionfale 5952, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Palermi+A%22">Palermi A</searchLink>; University Cardiology Division, SS Annunziata Polyclinic University Hospital, Chieti, Italy.<br /><searchLink fieldCode="AU" term="%22Pellegrino+A%22">Pellegrino A</searchLink>; Sports Medicine Center, University of Florence, Florence, Italy. Electronic address: alessio.pellegrino@unifi.it.<br /><searchLink fieldCode="AU" term="%22Pelliccia+A%22">Pelliccia A</searchLink>; Institute of Sport Medicine and Science, Italian National Olympic Committee, Largo Piero Gabrielli, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Quattrini+FM%22">Quattrini FM</searchLink>; Health Promotion, Prevention Plans and Sports Medicine Unit, Department of Prevention, ASL Roma 2, Rome, Italy. Electronic address: filippomaria.quattrini@aslroma2.it.<br /><searchLink fieldCode="AU" term="%22Ricci+F%22">Ricci F</searchLink>; University Cardiology Division, SS Annunziata Polyclinic University Hospital, Chieti, Italy. Electronic address: fabrizio.ricci@unich.it.<br /><searchLink fieldCode="AU" term="%22Scarzella+F%22">Scarzella F</searchLink>; Sports Medicine Institute, Turin, Italy. Electronic address: fiammetta.scarzella@imsto.it.<br /><searchLink fieldCode="AU" term="%22Squeo+MR%22">Squeo MR</searchLink>; Institute of Sport Medicine and Science, Italian National Olympic Committee, Largo Piero Gabrielli, Rome, Italy. Electronic address: mariarosaria.squeo@coni.it.<br /><searchLink fieldCode="AU" term="%22Tonelli+R%22">Tonelli R</searchLink>; Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Zanardo+E%22">Zanardo E</searchLink>; Sports and Exercise Medicine Division, Department of Medicine, University of Padova, Padova, Italy. Electronic address: Emanuele.zanardo@studenti.unipd.it.<br /><searchLink fieldCode="AU" term="%22Zorzi+A%22">Zorzi A</searchLink>; Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Peters+NS%22">Peters NS</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: n.peters@imperial.ac.uk.<br /><searchLink fieldCode="AU" term="%22Kramer+DB%22">Kramer DB</searchLink>; Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. Electronic address: dkramer@bidmc.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Waks+JW%22">Waks JW</searchLink>; Harvard-Thorndike Electrophysiology Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. Electronic address: jwaks@bidmc.harvard.edu.<br /><searchLink fieldCode="AU" term="%22De+Ferrari+GM%22">De Ferrari GM</searchLink>; Division of Cardiology, Cardiovascular and Thoracic Department, Città della Salute e della Scienza, Turin, Italy; Department of Medical Sciences, University of Turin, Turin, Italy. Electronic address: gaetano.deferrari@unito.it.<br /><searchLink fieldCode="AU" term="%22Ng+FS%22">Ng FS</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: f.ng@imperial.ac.uk.<br /><searchLink fieldCode="AU" term="%22Sau+A%22">Sau A</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: arunashis.sau09@imperial.ac.uk.<br /><searchLink fieldCode="AU" term="%22Saglietto+A%22">Saglietto A</searchLink>; Division of Cardiology, Cardiovascular and Thoracic Department, Città della Salute e della Scienza, Turin, Italy; Department of Medical Sciences, University of Turin, Turin, Italy.
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          Name:
            NameFull: Squeo MR
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          Name:
            NameFull: Tonelli R
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          Name:
            NameFull: Zanardo E
      – PersonEntity:
          Name:
            NameFull: Zorzi A
      – PersonEntity:
          Name:
            NameFull: Peters NS
      – PersonEntity:
          Name:
            NameFull: Kramer DB
      – PersonEntity:
          Name:
            NameFull: Waks JW
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            NameFull: De Ferrari GM
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            NameFull: Sau A
      – PersonEntity:
          Name:
            NameFull: Saglietto A
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          Dates:
            – D: 17
              M: 07
              Text: 2026 Jul 17
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1874-1754
          Numbering:
            – Type: volume
              Value: 461
          Titles:
            – TitleFull: International journal of cardiology
              Type: main
ResultId 1