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Real-world safety and effectiveness of enfortumab vedotin plus pembrolizumab in locally advanced or metastatic urothelial carcinoma: A multicenter Japanese cohort study.

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Title: Real-world safety and effectiveness of enfortumab vedotin plus pembrolizumab in locally advanced or metastatic urothelial carcinoma: A multicenter Japanese cohort study.
Authors: Yanagisawa T; Department of Urology, The Jikei University School of Medicine, Tokyo, Japan. Electronic address: t.yanagisawa.jikei@gmail.com., Iwatani K; Department of Urology, The Jikei University School of Medicine, Tokyo, Japan., Urabe F; Department of Urology, The Jikei University School of Medicine, Tokyo, Japan., Tsujino T; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan., Uchimoto T; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan., Inoki L; Department of Urology, Kindai University Faculty of Medicine, Osakasayama, Osaka, Japan., Hashimoto M; Department of Urology, Kindai University Faculty of Medicine, Osakasayama, Osaka, Japan., Yamamoto Y; Department of Urology, Kindai University Faculty of Medicine, Osakasayama, Osaka, Japan., Nukaya T; Department of Urology, Fujita-Health University School of Medicine, Toyoake, Aichi, Japan., Nishio K; Department of Urology, Kawasaki Medical School, Kurashiki, Okayama, Japan., Tamura K; Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan., Fukuokaya W; Department of Urology, The Jikei University School of Medicine, Tokyo, Japan., Takahara K; Department of Urology, Fujita-Health University School of Medicine, Toyoake, Aichi, Japan., Fujita K; Department of Urology, Kindai University Faculty of Medicine, Osakasayama, Osaka, Japan., Azuma H; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan., Inamoto T; Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan., Komura K; Department of Urology, Kawasaki Medical School, Kurashiki, Okayama, Japan., Kimura T; Department of Urology, The Jikei University School of Medicine, Tokyo, Japan.
Corporate Authors: ULTRA-J consortium
Source: Urologic oncology [Urol Oncol] 2026 Jul 17. Date of Electronic Publication: 2026 Jul 17.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9805460 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2496 (Electronic) Linking ISSN: 10781439 NLM ISO Abbreviation: Urol Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Real-world safety and effectiveness of enfortumab vedotin plus pembrolizumab in locally advanced or metastatic urothelial carcinoma: A multicenter Japanese cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Yanagisawa+T%22">Yanagisawa T</searchLink>; Department of Urology, The Jikei University School of Medicine, Tokyo, Japan. Electronic address: t.yanagisawa.jikei@gmail.com.<br /><searchLink fieldCode="AU" term="%22Iwatani+K%22">Iwatani K</searchLink>; Department of Urology, The Jikei University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Urabe+F%22">Urabe F</searchLink>; Department of Urology, The Jikei University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Tsujino+T%22">Tsujino T</searchLink>; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Uchimoto+T%22">Uchimoto T</searchLink>; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Inoki+L%22">Inoki L</searchLink>; Department of Urology, Kindai University Faculty of Medicine, Osakasayama, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Hashimoto+M%22">Hashimoto M</searchLink>; Department of Urology, Kindai University Faculty of Medicine, Osakasayama, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamoto+Y%22">Yamamoto Y</searchLink>; Department of Urology, Kindai University Faculty of Medicine, Osakasayama, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Nukaya+T%22">Nukaya T</searchLink>; Department of Urology, Fujita-Health University School of Medicine, Toyoake, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Nishio+K%22">Nishio K</searchLink>; Department of Urology, Kawasaki Medical School, Kurashiki, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Tamura+K%22">Tamura K</searchLink>; Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Fukuokaya+W%22">Fukuokaya W</searchLink>; Department of Urology, The Jikei University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Takahara+K%22">Takahara K</searchLink>; Department of Urology, Fujita-Health University School of Medicine, Toyoake, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Fujita+K%22">Fujita K</searchLink>; Department of Urology, Kindai University Faculty of Medicine, Osakasayama, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Azuma+H%22">Azuma H</searchLink>; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Inamoto+T%22">Inamoto T</searchLink>; Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Komura+K%22">Komura K</searchLink>; Department of Urology, Kawasaki Medical School, Kurashiki, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Kimura+T%22">Kimura T</searchLink>; Department of Urology, The Jikei University School of Medicine, Tokyo, Japan.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9805460 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-2496 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210781439%22">10781439 </searchLink><i>NLM ISO Abbreviation: </i>Urol Oncol <i>Subsets: </i>MEDLINE
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              Text: 2026 Jul 17
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