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HLH-like syndromes associate with increased risk of death and CD19-negative relapse post-CAR T in pediatric B-ALL.

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Title: HLH-like syndromes associate with increased risk of death and CD19-negative relapse post-CAR T in pediatric B-ALL.
Authors: McNerney KO; Northwestern University Feinberg School of Medicine, United States., Kwon S; Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States., Naik S; St Jude Children's Research Hospital, Memphis, Tennessee, United States., Fabrizio VA; University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States., Llaurador Caraballo G; Baylor College of Medicine, Texas Children's Hospital, Houston, Texas, United States., Sanchez-Pinto LN; Northwestern University Feinberg School of Medicine, United States., Talleur AC; St. Jude Children's Research Hospital, Memphis, Tennessee, United States., Zeng XL; Northwestern University Feinberg School of Medicine, United States., Baggott C; Stanford University School of Medicine, Stanford Cancer Institute, Stanford, California, United States., Vatsayan A; Children's National Hospital, Washington, District of Columbia, United States., Verneris MR; University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States., Prabhu S; Stanford University School of Medicine, Stanford Cancer Institute, Stanford, California, United States., Rossoff J; Northwestern University Feinberg School of Medicine, United States., Pacenta HL; Cook Children's Medical Center, Fort Worth, Texas, United States., Phillips CL; University of Cincinnati, United States., Talano JM; Medical College of Wisconsin, Milwaukee, Illinois, United States., Moskop A; Medical College of Wisconsin, Milwaukee, Wisconsin, United States., Myers GD; St. Jude Children's Research Hospital, Memphis, Tennessee, United States., Karras NA; City of Hope National Medical Center, Duarte, California, United States., Bonifant CL; Johns Hopkins University School of Medicine, Baltimore, Maryland, United States., Qayed M; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, and Emory University, Atlanta, Georgia, United States., Satwani P; Columbia University Medical Center, New York, New York, United States., Winestone LE; University of California San Francisco Benioff Children's Hospitals, San Fransisco, California, United States., Krupski C; University of Cincinnati, United States., Keating AK; Dana-Farber Cancer Institute and Boston Children's Hospital, boston, Massachusetts, United States., Baumeister SHC; Boston Children's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts, United States., Egeler E; Stanford University School of Medicine, Palo Alto, California, United States., Stieglitz E; UCSF Benioff Children's Hospitals, San Francisco, California, United States., Curran KJ; Memorial Sloan-Kettering Cancer Center, New York, New York, United States., Mackall CL; Parker Institute for Cancer Immunotherapy, United States., John S; Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, United States., Laetsch TW; Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States., Gardner RA; Seattle Children's Hospital, Seattle, Washington, United States., Schultz LM; Columbia University Medical Center, New York, New York, United States.
Source: Blood advances [Blood Adv] 2026 Jul 17. Date of Electronic Publication: 2026 Jul 17.
Publication Type: Journal Article
Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: HLH-like syndromes associate with increased risk of death and CD19-negative relapse post-CAR T in pediatric B-ALL.
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  Data: <searchLink fieldCode="AU" term="%22McNerney+KO%22">McNerney KO</searchLink>; Northwestern University Feinberg School of Medicine, United States.<br /><searchLink fieldCode="AU" term="%22Kwon+S%22">Kwon S</searchLink>; Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States.<br /><searchLink fieldCode="AU" term="%22Naik+S%22">Naik S</searchLink>; St Jude Children's Research Hospital, Memphis, Tennessee, United States.<br /><searchLink fieldCode="AU" term="%22Fabrizio+VA%22">Fabrizio VA</searchLink>; University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.<br /><searchLink fieldCode="AU" term="%22Llaurador+Caraballo+G%22">Llaurador Caraballo G</searchLink>; Baylor College of Medicine, Texas Children's Hospital, Houston, Texas, United States.<br /><searchLink fieldCode="AU" term="%22Sanchez-Pinto+LN%22">Sanchez-Pinto LN</searchLink>; Northwestern University Feinberg School of Medicine, United States.<br /><searchLink fieldCode="AU" term="%22Talleur+AC%22">Talleur AC</searchLink>; St. Jude Children's Research Hospital, Memphis, Tennessee, United States.<br /><searchLink fieldCode="AU" term="%22Zeng+XL%22">Zeng XL</searchLink>; Northwestern University Feinberg School of Medicine, United States.<br /><searchLink fieldCode="AU" term="%22Baggott+C%22">Baggott C</searchLink>; Stanford University School of Medicine, Stanford Cancer Institute, Stanford, California, United States.<br /><searchLink fieldCode="AU" term="%22Vatsayan+A%22">Vatsayan A</searchLink>; Children's National Hospital, Washington, District of Columbia, United States.<br /><searchLink fieldCode="AU" term="%22Verneris+MR%22">Verneris MR</searchLink>; University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.<br /><searchLink fieldCode="AU" term="%22Prabhu+S%22">Prabhu S</searchLink>; Stanford University School of Medicine, Stanford Cancer Institute, Stanford, California, United States.<br /><searchLink fieldCode="AU" term="%22Rossoff+J%22">Rossoff J</searchLink>; Northwestern University Feinberg School of Medicine, United States.<br /><searchLink fieldCode="AU" term="%22Pacenta+HL%22">Pacenta HL</searchLink>; Cook Children's Medical Center, Fort Worth, Texas, United States.<br /><searchLink fieldCode="AU" term="%22Phillips+CL%22">Phillips CL</searchLink>; University of Cincinnati, United States.<br /><searchLink fieldCode="AU" term="%22Talano+JM%22">Talano JM</searchLink>; Medical College of Wisconsin, Milwaukee, Illinois, United States.<br /><searchLink fieldCode="AU" term="%22Moskop+A%22">Moskop A</searchLink>; Medical College of Wisconsin, Milwaukee, Wisconsin, United States.<br /><searchLink fieldCode="AU" term="%22Myers+GD%22">Myers GD</searchLink>; St. Jude Children's Research Hospital, Memphis, Tennessee, United States.<br /><searchLink fieldCode="AU" term="%22Karras+NA%22">Karras NA</searchLink>; City of Hope National Medical Center, Duarte, California, United States.<br /><searchLink fieldCode="AU" term="%22Bonifant+CL%22">Bonifant CL</searchLink>; Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.<br /><searchLink fieldCode="AU" term="%22Qayed+M%22">Qayed M</searchLink>; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, and Emory University, Atlanta, Georgia, United States.<br /><searchLink fieldCode="AU" term="%22Satwani+P%22">Satwani P</searchLink>; Columbia University Medical Center, New York, New York, United States.<br /><searchLink fieldCode="AU" term="%22Winestone+LE%22">Winestone LE</searchLink>; University of California San Francisco Benioff Children's Hospitals, San Fransisco, California, United States.<br /><searchLink fieldCode="AU" term="%22Krupski+C%22">Krupski C</searchLink>; University of Cincinnati, United States.<br /><searchLink fieldCode="AU" term="%22Keating+AK%22">Keating AK</searchLink>; Dana-Farber Cancer Institute and Boston Children's Hospital, boston, Massachusetts, United States.<br /><searchLink fieldCode="AU" term="%22Baumeister+SHC%22">Baumeister SHC</searchLink>; Boston Children's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts, United States.<br /><searchLink fieldCode="AU" term="%22Egeler+E%22">Egeler E</searchLink>; Stanford University School of Medicine, Palo Alto, California, United States.<br /><searchLink fieldCode="AU" term="%22Stieglitz+E%22">Stieglitz E</searchLink>; UCSF Benioff Children's Hospitals, San Francisco, California, United States.<br /><searchLink fieldCode="AU" term="%22Curran+KJ%22">Curran KJ</searchLink>; Memorial Sloan-Kettering Cancer Center, New York, New York, United States.<br /><searchLink fieldCode="AU" term="%22Mackall+CL%22">Mackall CL</searchLink>; Parker Institute for Cancer Immunotherapy, United States.<br /><searchLink fieldCode="AU" term="%22John+S%22">John S</searchLink>; Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, United States.<br /><searchLink fieldCode="AU" term="%22Laetsch+TW%22">Laetsch TW</searchLink>; Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States.<br /><searchLink fieldCode="AU" term="%22Gardner+RA%22">Gardner RA</searchLink>; Seattle Children's Hospital, Seattle, Washington, United States.<br /><searchLink fieldCode="AU" term="%22Schultz+LM%22">Schultz LM</searchLink>; Columbia University Medical Center, New York, New York, United States.
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  Data: <searchLink fieldCode="JN" term="%22101698425%22">Blood advances</searchLink> [Blood Adv] 2026 Jul 17. <i>Date of Electronic Publication: </i>2026 Jul 17.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+of+Hematology%22">American Society of Hematology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101698425 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2473-9537 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224739529%22">24739529 </searchLink><i>NLM ISO Abbreviation: </i>Blood Adv <i>Subsets: </i>MEDLINE
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        Value: 10.1182/bloodadvances.2026020511
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              Text: 2026 Jul 17
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