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Psilocybin produces amplified acute responses and sex-specific long-term increases in sensorimotor gating in the mGlu5 knockout mouse model of schizophrenia.

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Title: Psilocybin produces amplified acute responses and sex-specific long-term increases in sensorimotor gating in the mGlu5 knockout mouse model of schizophrenia.
Authors: Gattuso JJ; Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.; Florey Department of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia., Kamal A; Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.; Department of Anatomy and Physiology, University of Melbourne, Parkville, VIC, Australia., Payet JM; Department of Psychology, Counselling and Therapy, School of Psychology and Public Health, La Trobe University, Melbourne, VIC, Australia., Havaux K; Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia., Hendey J; Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia., Bezcioglu B; Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.; Department of Anatomy and Physiology, University of Melbourne, Parkville, VIC, Australia., Phelan ZJ; Department of Psychology, Counselling and Therapy, School of Psychology and Public Health, La Trobe University, Melbourne, VIC, Australia., Orchard M; Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.; Department of Anatomy and Physiology, University of Melbourne, Parkville, VIC, Australia., Bhanot D; Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.; Department of Anatomy and Physiology, University of Melbourne, Parkville, VIC, Australia., Hale MW; Department of Psychology, Counselling and Therapy, School of Psychology and Public Health, La Trobe University, Melbourne, VIC, Australia., Hannan AJ; Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia. anthony.hannan@florey.edu.au.; Florey Department of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia. anthony.hannan@florey.edu.au.; Department of Anatomy and Physiology, University of Melbourne, Parkville, VIC, Australia. anthony.hannan@florey.edu.au., Renoir T; Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia. tibo.renoir@gmail.com.; Florey Department of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia. tibo.renoir@gmail.com.; Academic Quality Department, Melbourne Polytechnic, Melbourne, VIC, Australia. tibo.renoir@gmail.com.
Source: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2026 Jul 18. Date of Electronic Publication: 2026 Jul 18.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8904907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1740-634X (Electronic) Linking ISSN: 0893133X NLM ISO Abbreviation: Neuropsychopharmacology Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Gattuso+JJ%22">Gattuso JJ</searchLink>; Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.; Florey Department of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Kamal+A%22">Kamal A</searchLink>; Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.; Department of Anatomy and Physiology, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Payet+JM%22">Payet JM</searchLink>; Department of Psychology, Counselling and Therapy, School of Psychology and Public Health, La Trobe University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Havaux+K%22">Havaux K</searchLink>; Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Hendey+J%22">Hendey J</searchLink>; Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Bezcioglu+B%22">Bezcioglu B</searchLink>; Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.; Department of Anatomy and Physiology, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Phelan+ZJ%22">Phelan ZJ</searchLink>; Department of Psychology, Counselling and Therapy, School of Psychology and Public Health, La Trobe University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Orchard+M%22">Orchard M</searchLink>; Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.; Department of Anatomy and Physiology, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Bhanot+D%22">Bhanot D</searchLink>; Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.; Department of Anatomy and Physiology, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Hale+MW%22">Hale MW</searchLink>; Department of Psychology, Counselling and Therapy, School of Psychology and Public Health, La Trobe University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Hannan+AJ%22">Hannan AJ</searchLink>; Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia. anthony.hannan@florey.edu.au.; Florey Department of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia. anthony.hannan@florey.edu.au.; Department of Anatomy and Physiology, University of Melbourne, Parkville, VIC, Australia. anthony.hannan@florey.edu.au.<br /><searchLink fieldCode="AU" term="%22Renoir+T%22">Renoir T</searchLink>; Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia. tibo.renoir@gmail.com.; Florey Department of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia. tibo.renoir@gmail.com.; Academic Quality Department, Melbourne Polytechnic, Melbourne, VIC, Australia. tibo.renoir@gmail.com.
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