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Isotype-switched antibodies originating from tertiary lymphoid structures can antagonize ovarian cancer progression.

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Title: Isotype-switched antibodies originating from tertiary lymphoid structures can antagonize ovarian cancer progression.
Authors: Mandal G; Tumor Immunology and Immunotherapy, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, Maharashtra, India.; Homi Bhabha National Institute, Anushaktinagar, Mumbai 400094, Maharashtra, India., Biswas S; Tumor Immunology and Immunotherapy, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, Maharashtra, India.; Homi Bhabha National Institute, Anushaktinagar, Mumbai 400094, Maharashtra, India., Anadon CM; Department of Integrative Immunobiology, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27710, USA., Tamuli B; Tumor Immunology and Immunotherapy, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, Maharashtra, India.; Homi Bhabha National Institute, Anushaktinagar, Mumbai 400094, Maharashtra, India., Chaurio RA; Department of Integrative Immunobiology, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27710, USA., Lopez-Bailon LU; Department of Integrative Immunobiology, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27710, USA., Plappert N; Department of Integrative Immunobiology, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27710, USA., Carrion-Estrada D; Department of Integrative Immunobiology, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27710, USA., Mine JA; Department of Integrative Immunobiology, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27710, USA., Lai CH; Department of Integrative Immunobiology, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27710, USA., Moreno AP; Department of Integrative Immunobiology, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27710, USA., Johnson J; Analytic Microscopy Core, Tampa, FL 33612, USA., Moran-Segura CM; Advanced Analytical and Digital Laboratory, Tampa, FL 33619, USA., Fang B; Proteomics and Metabolomics Core, Memphis, TN 38163, USA., Marchion D; Tissue Core, Tampa, FL 33612, USA., Chaudhary N; Flow Cytometry Core, Tampa, FL 33612, USA., Terry KL; Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Sasamoto N; Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Program in Epidemiology, Public Health Sciences Division, Fred Hutch Cancer Center, Seattle, WA 98109, USA., Townsend MK; Division of Oncological Sciences, Oregon Health & Science University, Portland, OR 97201, USA., O'Brien J; Department of Medicine, Duke School of Medicine, Durham, NC 27710, USA., Antonia SJ; Department of Medicine, Duke School of Medicine, Durham, NC 27710, USA., Tworoger SS; Division of Oncological Sciences, Oregon Health & Science University, Portland, OR 97201, USA., Yu X; Department of Biostatistics and Bioinformatics, Tampa, FL 33612, USA., Rodriguez PC; Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA., Conejo-Garcia JR; Department of Integrative Immunobiology, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27710, USA.
Source: IScience [iScience] 2026 Jul 10; Vol. 29 (8), pp. 116757. Date of Electronic Publication: 2026 Jul 10 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
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  Data: Isotype-switched antibodies originating from tertiary lymphoid structures can antagonize ovarian cancer progression.
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  Data: <searchLink fieldCode="AU" term="%22Mandal+G%22">Mandal G</searchLink>; Tumor Immunology and Immunotherapy, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, Maharashtra, India.; Homi Bhabha National Institute, Anushaktinagar, Mumbai 400094, Maharashtra, India.<br /><searchLink fieldCode="AU" term="%22Biswas+S%22">Biswas S</searchLink>; Tumor Immunology and Immunotherapy, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, Maharashtra, India.; Homi Bhabha National Institute, Anushaktinagar, Mumbai 400094, Maharashtra, India.<br /><searchLink fieldCode="AU" term="%22Anadon+CM%22">Anadon CM</searchLink>; Department of Integrative Immunobiology, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Tamuli+B%22">Tamuli B</searchLink>; Tumor Immunology and Immunotherapy, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, Maharashtra, India.; Homi Bhabha National Institute, Anushaktinagar, Mumbai 400094, Maharashtra, India.<br /><searchLink fieldCode="AU" term="%22Chaurio+RA%22">Chaurio RA</searchLink>; Department of Integrative Immunobiology, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Lopez-Bailon+LU%22">Lopez-Bailon LU</searchLink>; Department of Integrative Immunobiology, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Plappert+N%22">Plappert N</searchLink>; Department of Integrative Immunobiology, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Carrion-Estrada+D%22">Carrion-Estrada D</searchLink>; Department of Integrative Immunobiology, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Mine+JA%22">Mine JA</searchLink>; Department of Integrative Immunobiology, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Lai+CH%22">Lai CH</searchLink>; Department of Integrative Immunobiology, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Moreno+AP%22">Moreno AP</searchLink>; Department of Integrative Immunobiology, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+J%22">Johnson J</searchLink>; Analytic Microscopy Core, Tampa, FL 33612, USA.<br /><searchLink fieldCode="AU" term="%22Moran-Segura+CM%22">Moran-Segura CM</searchLink>; Advanced Analytical and Digital Laboratory, Tampa, FL 33619, USA.<br /><searchLink fieldCode="AU" term="%22Fang+B%22">Fang B</searchLink>; Proteomics and Metabolomics Core, Memphis, TN 38163, USA.<br /><searchLink fieldCode="AU" term="%22Marchion+D%22">Marchion D</searchLink>; Tissue Core, Tampa, FL 33612, USA.<br /><searchLink fieldCode="AU" term="%22Chaudhary+N%22">Chaudhary N</searchLink>; Flow Cytometry Core, Tampa, FL 33612, USA.<br /><searchLink fieldCode="AU" term="%22Terry+KL%22">Terry KL</searchLink>; Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Sasamoto+N%22">Sasamoto N</searchLink>; Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Program in Epidemiology, Public Health Sciences Division, Fred Hutch Cancer Center, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Townsend+MK%22">Townsend MK</searchLink>; Division of Oncological Sciences, Oregon Health & Science University, Portland, OR 97201, USA.<br /><searchLink fieldCode="AU" term="%22O'Brien+J%22">O'Brien J</searchLink>; Department of Medicine, Duke School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Antonia+SJ%22">Antonia SJ</searchLink>; Department of Medicine, Duke School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Tworoger+SS%22">Tworoger SS</searchLink>; Division of Oncological Sciences, Oregon Health & Science University, Portland, OR 97201, USA.<br /><searchLink fieldCode="AU" term="%22Yu+X%22">Yu X</searchLink>; Department of Biostatistics and Bioinformatics, Tampa, FL 33612, USA.<br /><searchLink fieldCode="AU" term="%22Rodriguez+PC%22">Rodriguez PC</searchLink>; Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.<br /><searchLink fieldCode="AU" term="%22Conejo-Garcia+JR%22">Conejo-Garcia JR</searchLink>; Department of Integrative Immunobiology, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27710, USA.
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