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NADPH oxidase 2 (NOX2)-independent inducers of neutrophil extracellular traps promote resolution of chronic inflammation.

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Title: NADPH oxidase 2 (NOX2)-independent inducers of neutrophil extracellular traps promote resolution of chronic inflammation.
Authors: Euler M; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany., Hattab O; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany., Borah Slater K; Biosciences, Faculty of Health and Life Sciences, University of Exeter, EX4 4QD, United Kingdom., Golub B; Friedrich-Alexander University Erlangen-Nürnberg (FAU), Department of Chemistry and Pharmacy, Organic Chemistry Chair II, Erlangen, Germany., Selin R; Friedrich-Alexander University Erlangen-Nürnberg (FAU), Department of Chemistry and Pharmacy, Organic Chemistry Chair II, Erlangen, Germany., Cheng Z; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany., Maluje Villanueva YA; Medical Systems Biology, Institute of Experimental Dermatology, University of Lübeck, Lübeck, 23562, Germany., Özkan GH; Friedrich-Alexander University Erlangen-Nürnberg (FAU), Department of Chemistry and Pharmacy, Organic Chemistry Chair II, Erlangen, Germany., Bila G; Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Bucharest, Romania; Department of Histology, Cytology and Embryology, Danylo Halytsky Lviv National Medical University, Lviv, 79010, Ukraine., Dutta K; University of Luebeck, Department of Dermatology, Lübeck, 23562, Germany., Weidner D; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany., Hoffmann EJ; University of Luebeck, Institute for Systemic Inflammation Research, Lübeck, 23562, Germany., Friscic J; University of Luebeck, Institute for Systemic Inflammation Research, Lübeck, 23562, Germany., Sadik CD; University of Luebeck, Department of Dermatology, Lübeck, 23562, Germany., Harrer T; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany., Köhl J; University of Luebeck, Institute for Systemic Inflammation Research, Lübeck, 23562, Germany., Schett G; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany., Munoz L; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany., Fähnrich A; Medical Systems Biology, Institute of Experimental Dermatology, University of Lübeck, Lübeck, 23562, Germany., Murthy S; University of Luebeck, Department of Dermatology, Lübeck, 23562, Germany., Grieshaber-Bouyer R; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany., Herrmann M; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, 610041, China., Bilyy R; Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Bucharest, Romania; Department of Histology, Cytology and Embryology, Danylo Halytsky Lviv National Medical University, Lviv, 79010, Ukraine., Griffiths HR; Swansea University Medical School, Swansea University, Swansea, United Kingdom., Mokhir A; Friedrich-Alexander University Erlangen-Nürnberg (FAU), Department of Chemistry and Pharmacy, Organic Chemistry Chair II, Erlangen, Germany., Hoffmann MH; University of Luebeck, Department of Dermatology, Lübeck, 23562, Germany; University of Luebeck, Institute for Systemic Inflammation Research, Lübeck, 23562, Germany. Electronic address: Markus.hoffmann@uni-luebeck.de.
Source: Redox biology [Redox Biol] 2026 Sep; Vol. 95, pp. 104302. Date of Electronic Publication: 2026 Jul 15.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2317 (Electronic) Linking ISSN: 22132317 NLM ISO Abbreviation: Redox Biol Subsets: MEDLINE
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  Data: NADPH oxidase 2 (NOX2)-independent inducers of neutrophil extracellular traps promote resolution of chronic inflammation.
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  Data: <searchLink fieldCode="AU" term="%22Euler+M%22">Euler M</searchLink>; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Hattab+O%22">Hattab O</searchLink>; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Borah+Slater+K%22">Borah Slater K</searchLink>; Biosciences, Faculty of Health and Life Sciences, University of Exeter, EX4 4QD, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Golub+B%22">Golub B</searchLink>; Friedrich-Alexander University Erlangen-Nürnberg (FAU), Department of Chemistry and Pharmacy, Organic Chemistry Chair II, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Selin+R%22">Selin R</searchLink>; Friedrich-Alexander University Erlangen-Nürnberg (FAU), Department of Chemistry and Pharmacy, Organic Chemistry Chair II, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Cheng+Z%22">Cheng Z</searchLink>; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Maluje+Villanueva+YA%22">Maluje Villanueva YA</searchLink>; Medical Systems Biology, Institute of Experimental Dermatology, University of Lübeck, Lübeck, 23562, Germany.<br /><searchLink fieldCode="AU" term="%22Özkan+GH%22">Özkan GH</searchLink>; Friedrich-Alexander University Erlangen-Nürnberg (FAU), Department of Chemistry and Pharmacy, Organic Chemistry Chair II, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Bila+G%22">Bila G</searchLink>; Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Bucharest, Romania; Department of Histology, Cytology and Embryology, Danylo Halytsky Lviv National Medical University, Lviv, 79010, Ukraine.<br /><searchLink fieldCode="AU" term="%22Dutta+K%22">Dutta K</searchLink>; University of Luebeck, Department of Dermatology, Lübeck, 23562, Germany.<br /><searchLink fieldCode="AU" term="%22Weidner+D%22">Weidner D</searchLink>; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Hoffmann+EJ%22">Hoffmann EJ</searchLink>; University of Luebeck, Institute for Systemic Inflammation Research, Lübeck, 23562, Germany.<br /><searchLink fieldCode="AU" term="%22Friscic+J%22">Friscic J</searchLink>; University of Luebeck, Institute for Systemic Inflammation Research, Lübeck, 23562, Germany.<br /><searchLink fieldCode="AU" term="%22Sadik+CD%22">Sadik CD</searchLink>; University of Luebeck, Department of Dermatology, Lübeck, 23562, Germany.<br /><searchLink fieldCode="AU" term="%22Harrer+T%22">Harrer T</searchLink>; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Köhl+J%22">Köhl J</searchLink>; University of Luebeck, Institute for Systemic Inflammation Research, Lübeck, 23562, Germany.<br /><searchLink fieldCode="AU" term="%22Schett+G%22">Schett G</searchLink>; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Munoz+L%22">Munoz L</searchLink>; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Fähnrich+A%22">Fähnrich A</searchLink>; Medical Systems Biology, Institute of Experimental Dermatology, University of Lübeck, Lübeck, 23562, Germany.<br /><searchLink fieldCode="AU" term="%22Murthy+S%22">Murthy S</searchLink>; University of Luebeck, Department of Dermatology, Lübeck, 23562, Germany.<br /><searchLink fieldCode="AU" term="%22Grieshaber-Bouyer+R%22">Grieshaber-Bouyer R</searchLink>; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Herrmann+M%22">Herrmann M</searchLink>; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany; Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, 610041, China.<br /><searchLink fieldCode="AU" term="%22Bilyy+R%22">Bilyy R</searchLink>; Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Bucharest, Romania; Department of Histology, Cytology and Embryology, Danylo Halytsky Lviv National Medical University, Lviv, 79010, Ukraine.<br /><searchLink fieldCode="AU" term="%22Griffiths+HR%22">Griffiths HR</searchLink>; Swansea University Medical School, Swansea University, Swansea, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Mokhir+A%22">Mokhir A</searchLink>; Friedrich-Alexander University Erlangen-Nürnberg (FAU), Department of Chemistry and Pharmacy, Organic Chemistry Chair II, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Hoffmann+MH%22">Hoffmann MH</searchLink>; University of Luebeck, Department of Dermatology, Lübeck, 23562, Germany; University of Luebeck, Institute for Systemic Inflammation Research, Lübeck, 23562, Germany. Electronic address: Markus.hoffmann@uni-luebeck.de.
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