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Use of blood-based neurofilament light chain as an endpoint in clinical trials of neurodegenerative conditions: a scoping review.

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Title: Use of blood-based neurofilament light chain as an endpoint in clinical trials of neurodegenerative conditions: a scoping review.
Authors: Zheng Y; Melbourne Medical School, The University of Melbourne, Parkville, VIC, Australia., Bhalala OG; Department of Medicine, Royal Melbourne Hospital, Parkville, VIC, Australia.; Genetics and Gene Regulation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Melbourne Brain Centre, The Royal Melbourne Hospital, University of Melbourne, Parkville, Australia., Chin KS; Department of Medicine, Royal Melbourne Hospital, Parkville, VIC, Australia.; Melbourne Brain Centre, The Royal Melbourne Hospital, University of Melbourne, Parkville, Australia.; Department of Aged Care, The Royal Melbourne Hospital, Parkville, VIC, Australia., Watson R; Department of Medicine, Royal Melbourne Hospital, Parkville, VIC, Australia.; Melbourne Brain Centre, The Royal Melbourne Hospital, University of Melbourne, Parkville, Australia., Yassi N; Department of Medicine, Royal Melbourne Hospital, Parkville, VIC, Australia. nawaf.yassi@unimelb.edu.au.; Melbourne Brain Centre, The Royal Melbourne Hospital, University of Melbourne, Parkville, Australia. nawaf.yassi@unimelb.edu.au.; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Australia. nawaf.yassi@unimelb.edu.au.
Source: Journal of neurology [J Neurol] 2026 Jul 20; Vol. 273 (8). Date of Electronic Publication: 2026 Jul 20.
Publication Type: Journal Article; Scoping Review; Review
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0423161 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1459 (Electronic) Linking ISSN: 03405354 NLM ISO Abbreviation: J Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Use of blood-based neurofilament light chain as an endpoint in clinical trials of neurodegenerative conditions: a scoping review.
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  Data: <searchLink fieldCode="AU" term="%22Zheng+Y%22">Zheng Y</searchLink>; Melbourne Medical School, The University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Bhalala+OG%22">Bhalala OG</searchLink>; Department of Medicine, Royal Melbourne Hospital, Parkville, VIC, Australia.; Genetics and Gene Regulation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Melbourne Brain Centre, The Royal Melbourne Hospital, University of Melbourne, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Chin+KS%22">Chin KS</searchLink>; Department of Medicine, Royal Melbourne Hospital, Parkville, VIC, Australia.; Melbourne Brain Centre, The Royal Melbourne Hospital, University of Melbourne, Parkville, Australia.; Department of Aged Care, The Royal Melbourne Hospital, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Watson+R%22">Watson R</searchLink>; Department of Medicine, Royal Melbourne Hospital, Parkville, VIC, Australia.; Melbourne Brain Centre, The Royal Melbourne Hospital, University of Melbourne, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Yassi+N%22">Yassi N</searchLink>; Department of Medicine, Royal Melbourne Hospital, Parkville, VIC, Australia. nawaf.yassi@unimelb.edu.au.; Melbourne Brain Centre, The Royal Melbourne Hospital, University of Melbourne, Parkville, Australia. nawaf.yassi@unimelb.edu.au.; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Australia. nawaf.yassi@unimelb.edu.au.
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  Data: <searchLink fieldCode="JN" term="%220423161%22">Journal of neurology</searchLink> [J Neurol] 2026 Jul 20; Vol. 273 (8). <i>Date of Electronic Publication: </i>2026 Jul 20.
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        Value: 10.1007/s00415-026-14007-5
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        Text: English
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      – TitleFull: Use of blood-based neurofilament light chain as an endpoint in clinical trials of neurodegenerative conditions: a scoping review.
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            NameFull: Zheng Y
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              Text: 2026 Jul 20
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