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Route-Dependent Therapeutic Effects and Tissue Retention of Mesenchymal Stem Cell-Derived Exosomes in a Murine Model of Stevens-Johnson Syndrome.

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Title: Route-Dependent Therapeutic Effects and Tissue Retention of Mesenchymal Stem Cell-Derived Exosomes in a Murine Model of Stevens-Johnson Syndrome.
Authors: Khodor A; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States., Ma S; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States.; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States., Komai S; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States.; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States.; Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan., Tomioka Y; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States.; Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan., Moreira Dos Santos C; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States., de Castro LL; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States., Mezzich GC; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States., Quiroga-Garza ME; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States.; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States., Ruiz-Lozano RE; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States.; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States., Mousa H; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States., Ong HS; Corneal and External Diseases Department, Singapore National Eye Centre, Singapore, Singapore.; Regenerative Therapy Research Group, Singapore Eye Research Institute, Singapore, Singapore.; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore, Singapore., Riau AK; Corneal and External Diseases Department, Singapore National Eye Centre, Singapore, Singapore.; Regenerative Therapy Research Group, Singapore Eye Research Institute, Singapore, Singapore.; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore, Singapore., Littleton S; Department of Immunology, Duke University School of Medicine, Durham, North Carolina, United States., Ueta M; Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan., Mehta JS; Corneal and External Diseases Department, Singapore National Eye Centre, Singapore, Singapore.; Regenerative Therapy Research Group, Singapore Eye Research Institute, Singapore, Singapore.; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore, Singapore., Saban DR; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States.; Department of Immunology, Duke University School of Medicine, Durham, North Carolina, United States., Perez VL; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States.; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States.
Source: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2026 Jul 01; Vol. 67 (8), pp. 44.
Publication Type: Journal Article
Journal Info: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE
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  Data: Route-Dependent Therapeutic Effects and Tissue Retention of Mesenchymal Stem Cell-Derived Exosomes in a Murine Model of Stevens-Johnson Syndrome.
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  Data: <searchLink fieldCode="AU" term="%22Khodor+A%22">Khodor A</searchLink>; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States.<br /><searchLink fieldCode="AU" term="%22Ma+S%22">Ma S</searchLink>; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States.; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States.<br /><searchLink fieldCode="AU" term="%22Komai+S%22">Komai S</searchLink>; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States.; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States.; Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Tomioka+Y%22">Tomioka Y</searchLink>; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States.; Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Moreira+Dos+Santos+C%22">Moreira Dos Santos C</searchLink>; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States.<br /><searchLink fieldCode="AU" term="%22de+Castro+LL%22">de Castro LL</searchLink>; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States.<br /><searchLink fieldCode="AU" term="%22Mezzich+GC%22">Mezzich GC</searchLink>; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States.<br /><searchLink fieldCode="AU" term="%22Quiroga-Garza+ME%22">Quiroga-Garza ME</searchLink>; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States.; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States.<br /><searchLink fieldCode="AU" term="%22Ruiz-Lozano+RE%22">Ruiz-Lozano RE</searchLink>; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States.; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States.<br /><searchLink fieldCode="AU" term="%22Mousa+H%22">Mousa H</searchLink>; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States.<br /><searchLink fieldCode="AU" term="%22Ong+HS%22">Ong HS</searchLink>; Corneal and External Diseases Department, Singapore National Eye Centre, Singapore, Singapore.; Regenerative Therapy Research Group, Singapore Eye Research Institute, Singapore, Singapore.; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Riau+AK%22">Riau AK</searchLink>; Corneal and External Diseases Department, Singapore National Eye Centre, Singapore, Singapore.; Regenerative Therapy Research Group, Singapore Eye Research Institute, Singapore, Singapore.; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Littleton+S%22">Littleton S</searchLink>; Department of Immunology, Duke University School of Medicine, Durham, North Carolina, United States.<br /><searchLink fieldCode="AU" term="%22Ueta+M%22">Ueta M</searchLink>; Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Mehta+JS%22">Mehta JS</searchLink>; Corneal and External Diseases Department, Singapore National Eye Centre, Singapore, Singapore.; Regenerative Therapy Research Group, Singapore Eye Research Institute, Singapore, Singapore.; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Saban+DR%22">Saban DR</searchLink>; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States.; Department of Immunology, Duke University School of Medicine, Durham, North Carolina, United States.<br /><searchLink fieldCode="AU" term="%22Perez+VL%22">Perez VL</searchLink>; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States.; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States.
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