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Catecholamine-mediated release of miR-133a-3p from adipocytes regulates the onset of chronic primary pain.

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Title: Catecholamine-mediated release of miR-133a-3p from adipocytes regulates the onset of chronic primary pain.
Authors: Hernandez NP; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University School of Medicine, Durham, United States of America., Chen J; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University School of Medicine, Durham, United States of America., Qian Y; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University School of Medicine, Durham, United States of America., Zhang X; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University School of Medicine, Durham, United States of America., Wang Y; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University School of Medicine, Durham, United States of America., Ciszek BP; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University School of Medicine, Durham, United States of America., Gao X; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University School of Medicine, Durham, United States of America., Klein ME; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University School of Medicine, Durham, United States of America., Pai YL; Department of Cell Biology & Physiology, Washington University School of Medicine in St. Louis, St. Louis, United States of America., Karaky M; Faculty of Medicine and Health Sciences, The Alan Edwards Centre for Research on Pain, McGill University, Montréal,, Canada., Meloto CB; Faculty of Medicine and Health Sciences, The Alan Edwards Centre for Research on Pain, McGill University, Montréal,, Canada., Montagna F; Faculty of Medicine and Health Sciences, The Alan Edwards Centre for Research on Pain, McGill University, Montréal,, Canada., Kanke M; Department of Biomedical Sciences, Cornell University College of Veterinary Medicine, Ithaca, United States of America., Crewe C; Department of Cell Biology & Physiology, Washington University School of Medicine in St. Louis, St. Louis, United States of America., Diatchenko L; Faculty of Medicine and Health Sciences, The Alan Edwards Centre for Research on Pain, McGill University, Montréal,, Canada., Sethupathy P; Department of Biomedical Sciences, Cornell University College of Veterinary Medicine, Ithaca, United States of America., Nackley AG; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University School of Medicine, Durham, United States of America.
Source: The Journal of clinical investigation [J Clin Invest] 2026 Jul 21. Date of Electronic Publication: 2026 Jul 21.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
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  Data: Catecholamine-mediated release of miR-133a-3p from adipocytes regulates the onset of chronic primary pain.
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  Data: <searchLink fieldCode="AU" term="%22Hernandez+NP%22">Hernandez NP</searchLink>; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University School of Medicine, Durham, United States of America.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University School of Medicine, Durham, United States of America.<br /><searchLink fieldCode="AU" term="%22Qian+Y%22">Qian Y</searchLink>; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University School of Medicine, Durham, United States of America.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University School of Medicine, Durham, United States of America.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University School of Medicine, Durham, United States of America.<br /><searchLink fieldCode="AU" term="%22Ciszek+BP%22">Ciszek BP</searchLink>; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University School of Medicine, Durham, United States of America.<br /><searchLink fieldCode="AU" term="%22Gao+X%22">Gao X</searchLink>; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University School of Medicine, Durham, United States of America.<br /><searchLink fieldCode="AU" term="%22Klein+ME%22">Klein ME</searchLink>; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University School of Medicine, Durham, United States of America.<br /><searchLink fieldCode="AU" term="%22Pai+YL%22">Pai YL</searchLink>; Department of Cell Biology & Physiology, Washington University School of Medicine in St. Louis, St. Louis, United States of America.<br /><searchLink fieldCode="AU" term="%22Karaky+M%22">Karaky M</searchLink>; Faculty of Medicine and Health Sciences, The Alan Edwards Centre for Research on Pain, McGill University, Montréal,, Canada.<br /><searchLink fieldCode="AU" term="%22Meloto+CB%22">Meloto CB</searchLink>; Faculty of Medicine and Health Sciences, The Alan Edwards Centre for Research on Pain, McGill University, Montréal,, Canada.<br /><searchLink fieldCode="AU" term="%22Montagna+F%22">Montagna F</searchLink>; Faculty of Medicine and Health Sciences, The Alan Edwards Centre for Research on Pain, McGill University, Montréal,, Canada.<br /><searchLink fieldCode="AU" term="%22Kanke+M%22">Kanke M</searchLink>; Department of Biomedical Sciences, Cornell University College of Veterinary Medicine, Ithaca, United States of America.<br /><searchLink fieldCode="AU" term="%22Crewe+C%22">Crewe C</searchLink>; Department of Cell Biology & Physiology, Washington University School of Medicine in St. Louis, St. Louis, United States of America.<br /><searchLink fieldCode="AU" term="%22Diatchenko+L%22">Diatchenko L</searchLink>; Faculty of Medicine and Health Sciences, The Alan Edwards Centre for Research on Pain, McGill University, Montréal,, Canada.<br /><searchLink fieldCode="AU" term="%22Sethupathy+P%22">Sethupathy P</searchLink>; Department of Biomedical Sciences, Cornell University College of Veterinary Medicine, Ithaca, United States of America.<br /><searchLink fieldCode="AU" term="%22Nackley+AG%22">Nackley AG</searchLink>; Department of Anesthesiology, Center for Translational Pain Medicine, Duke University School of Medicine, Durham, United States of America.
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