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Development and characterization of [47Sc]Sc-NOTA-trastuzumab for targeted radiotherapy in primary and metastatic HER2 + breast cancer.

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Title: Development and characterization of [47Sc]Sc-NOTA-trastuzumab for targeted radiotherapy in primary and metastatic HER2 + breast cancer.
Authors: Song PN; Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA; Graduate Biomedical Sciences, The University of Alabama at Birmingham, Birmingham, USA., Cingoranelli SJ; Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA; Department of Chemistry, The University of Alabama at Birmingham, Birmingham, USA., Sridhar S; Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA., Houson HA; Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA; Department of Chemistry, The University of Alabama at Birmingham, Birmingham, USA., Gallegos CA; Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA; Department of Biomedical Engineering, The University of Alabama at Birmingham, Birmingham, USA., Watts LB; Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA., Bartels JL; Department of Chemistry, The University of Alabama at Birmingham, Birmingham, USA., Willey CD; Department of Radiation Oncology, The University of Alabama at Birmingham, Birmingham, USA; O'Neal Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, USA., Lapi SE; Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA; Department of Chemistry, The University of Alabama at Birmingham, Birmingham, USA; O'Neal Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, USA. Electronic address: lapi@uab.edu., Sorace AG; Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA; Department of Biomedical Engineering, The University of Alabama at Birmingham, Birmingham, USA; O'Neal Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, USA. Electronic address: asorace@uabmc.edu.
Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2026 Jul 21; Vol. 202, pp. 119736. Date of Electronic Publication: 2026 Jul 21.
Publication Type: Journal Article
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE
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  Data: Development and characterization of [<superscript>47</superscript>Sc]Sc-NOTA-trastuzumab for targeted radiotherapy in primary and metastatic HER2 + breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22Song+PN%22">Song PN</searchLink>; Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA; Graduate Biomedical Sciences, The University of Alabama at Birmingham, Birmingham, USA.<br /><searchLink fieldCode="AU" term="%22Cingoranelli+SJ%22">Cingoranelli SJ</searchLink>; Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA; Department of Chemistry, The University of Alabama at Birmingham, Birmingham, USA.<br /><searchLink fieldCode="AU" term="%22Sridhar+S%22">Sridhar S</searchLink>; Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA.<br /><searchLink fieldCode="AU" term="%22Houson+HA%22">Houson HA</searchLink>; Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA; Department of Chemistry, The University of Alabama at Birmingham, Birmingham, USA.<br /><searchLink fieldCode="AU" term="%22Gallegos+CA%22">Gallegos CA</searchLink>; Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA; Department of Biomedical Engineering, The University of Alabama at Birmingham, Birmingham, USA.<br /><searchLink fieldCode="AU" term="%22Watts+LB%22">Watts LB</searchLink>; Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA.<br /><searchLink fieldCode="AU" term="%22Bartels+JL%22">Bartels JL</searchLink>; Department of Chemistry, The University of Alabama at Birmingham, Birmingham, USA.<br /><searchLink fieldCode="AU" term="%22Willey+CD%22">Willey CD</searchLink>; Department of Radiation Oncology, The University of Alabama at Birmingham, Birmingham, USA; O'Neal Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, USA.<br /><searchLink fieldCode="AU" term="%22Lapi+SE%22">Lapi SE</searchLink>; Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA; Department of Chemistry, The University of Alabama at Birmingham, Birmingham, USA; O'Neal Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, USA. Electronic address: lapi@uab.edu.<br /><searchLink fieldCode="AU" term="%22Sorace+AG%22">Sorace AG</searchLink>; Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA; Department of Biomedical Engineering, The University of Alabama at Birmingham, Birmingham, USA; O'Neal Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, USA. Electronic address: asorace@uabmc.edu.
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  Data: <searchLink fieldCode="JN" term="%228213295%22">Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie</searchLink> [Biomed Pharmacother] 2026 Jul 21; Vol. 202, pp. 119736. <i>Date of Electronic Publication: </i>2026 Jul 21.
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              Text: 2026 Jul 21
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