Deciphering the prodrome of inflammatory bowel disease up to 10 years before disease onset by massively parallel serology.

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Title: Deciphering the prodrome of inflammatory bowel disease up to 10 years before disease onset by massively parallel serology.
Authors: Bourgonje AR; Department of Medicine, Division of Gastroenterology, Icahn School of Medicine, New York, New York, USA.; Precision Immunology Institute, Icahn School of Medicine, New York, New York, USA.; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., Innocenti G; Center for Cancer Research, Medical University of Vienna, Vienna, Austria., Livanos AE; Department of Medicine, Division of Gastroenterology, Icahn School of Medicine, New York, New York, USA.; Precision Immunology Institute, Icahn School of Medicine, New York, New York, USA., Prinzensteiner M; Center for Cancer Research, Medical University of Vienna, Vienna, Austria., Magee JS; Gastroenterology, Walter Reed National Military Medical Center, Bethesda, Maryland, USA., Riddle MS; Pfizer Inc, New York, New York, USA., Laird RM; Department of Diarrheal Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA., Dervieux T; Prometheus Laboratories, Prometheus Biosciences Inc, San Diego, California, USA., Porter CK; Translational and Clinical Research Department, Naval Medical Research Command, Silver Spring, Maryland, USA., Gnjatic S; Precision Immunology Institute, Icahn School of Medicine, New York, New York, USA.; Human Immune Monitoring Center, Icahn School of Medicine, New York, New York, USA.; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Petralia F; Department of Genetics and Genomics Sciences, Icahn School of Medicine, New York, New York, USA., Torres J; Department of Medicine, Division of Gastroenterology, Icahn School of Medicine, New York, New York, USA.; Gastroenterology Division, Hospital Beatriz Angelo, Loures, Portugal.; Gastroenterology Division, Hospital da Luz, Lisbon, Portugal.; Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., Suárez-Fariñas M; Department of Genetics and Genomics Sciences, Icahn School of Medicine, New York, New York, USA., Vogl T; Center for Cancer Research, Medical University of Vienna, Vienna, Austria saurabh.mehandru@mssm.edu Jean-frederic.colombel@mssm.edu thomas.vogl@meduniwien.ac.at., Colombel JF; Department of Medicine, Division of Gastroenterology, Icahn School of Medicine, New York, New York, USA saurabh.mehandru@mssm.edu Jean-frederic.colombel@mssm.edu thomas.vogl@meduniwien.ac.at.; Precision Immunology Institute, Icahn School of Medicine, New York, New York, USA., Mehandru S; Department of Medicine, Division of Gastroenterology, Icahn School of Medicine, New York, New York, USA saurabh.mehandru@mssm.edu Jean-frederic.colombel@mssm.edu thomas.vogl@meduniwien.ac.at.; Precision Immunology Institute, Icahn School of Medicine, New York, New York, USA.
Source: Gut [Gut] 2026 Jul 23. Date of Electronic Publication: 2026 Jul 23.
Publication Type: Journal Article
Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Bourgonje+AR%22">Bourgonje AR</searchLink>; Department of Medicine, Division of Gastroenterology, Icahn School of Medicine, New York, New York, USA.; Precision Immunology Institute, Icahn School of Medicine, New York, New York, USA.; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Innocenti+G%22">Innocenti G</searchLink>; Center for Cancer Research, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Livanos+AE%22">Livanos AE</searchLink>; Department of Medicine, Division of Gastroenterology, Icahn School of Medicine, New York, New York, USA.; Precision Immunology Institute, Icahn School of Medicine, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Prinzensteiner+M%22">Prinzensteiner M</searchLink>; Center for Cancer Research, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Magee+JS%22">Magee JS</searchLink>; Gastroenterology, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Riddle+MS%22">Riddle MS</searchLink>; Pfizer Inc, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Laird+RM%22">Laird RM</searchLink>; Department of Diarrheal Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Dervieux+T%22">Dervieux T</searchLink>; Prometheus Laboratories, Prometheus Biosciences Inc, San Diego, California, USA.<br /><searchLink fieldCode="AU" term="%22Porter+CK%22">Porter CK</searchLink>; Translational and Clinical Research Department, Naval Medical Research Command, Silver Spring, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Gnjatic+S%22">Gnjatic S</searchLink>; Precision Immunology Institute, Icahn School of Medicine, New York, New York, USA.; Human Immune Monitoring Center, Icahn School of Medicine, New York, New York, USA.; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Petralia+F%22">Petralia F</searchLink>; Department of Genetics and Genomics Sciences, Icahn School of Medicine, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Torres+J%22">Torres J</searchLink>; Department of Medicine, Division of Gastroenterology, Icahn School of Medicine, New York, New York, USA.; Gastroenterology Division, Hospital Beatriz Angelo, Loures, Portugal.; Gastroenterology Division, Hospital da Luz, Lisbon, Portugal.; Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Suárez-Fariñas+M%22">Suárez-Fariñas M</searchLink>; Department of Genetics and Genomics Sciences, Icahn School of Medicine, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Vogl+T%22">Vogl T</searchLink>; Center for Cancer Research, Medical University of Vienna, Vienna, Austria saurabh.mehandru@mssm.edu Jean-frederic.colombel@mssm.edu thomas.vogl@meduniwien.ac.at.<br /><searchLink fieldCode="AU" term="%22Colombel+JF%22">Colombel JF</searchLink>; Department of Medicine, Division of Gastroenterology, Icahn School of Medicine, New York, New York, USA saurabh.mehandru@mssm.edu Jean-frederic.colombel@mssm.edu thomas.vogl@meduniwien.ac.at.; Precision Immunology Institute, Icahn School of Medicine, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Mehandru+S%22">Mehandru S</searchLink>; Department of Medicine, Division of Gastroenterology, Icahn School of Medicine, New York, New York, USA saurabh.mehandru@mssm.edu Jean-frederic.colombel@mssm.edu thomas.vogl@meduniwien.ac.at.; Precision Immunology Institute, Icahn School of Medicine, New York, New York, USA.
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        Value: 10.1136/gutjnl-2025-337762
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