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Increased phenotypic and functional stability of human allospecific induced Tregs is associated with Vitamin C-mediated FOXP3 TSDR demethylation.

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Title: Increased phenotypic and functional stability of human allospecific induced Tregs is associated with Vitamin C-mediated FOXP3 TSDR demethylation.
Authors: Alvarez-Salazar EK; Department of Immunology, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico.; National Laboratory of Flow Cytometry, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico., Reyes-Barrientos JE; Department of Immunology, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico.; National Laboratory of Flow Cytometry, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico., Cortés-Hernández A; Department of Immunology, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico., Saint-Martin Castellanos A; Department of Immunology, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico., Arteaga-Cruz S; Department of Immunology, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico., Cervera A; Biomedical Genomics and Bioinformatics Laboratory, Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Martínez-Iturbe I; Department of Immunology, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico., Sánchez-Hernández BE; Department of Pathology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Gamboa-Domínguez A; Department of Pathology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Soldevila G; Department of Immunology, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico.; National Laboratory of Flow Cytometry, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico.
Source: Frontiers in immunology [Front Immunol] 2026 Jul 08; Vol. 17, pp. 1827886. Date of Electronic Publication: 2026 Jul 08 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Increased phenotypic and functional stability of human allospecific induced Tregs is associated with Vitamin C-mediated FOXP3 TSDR demethylation.
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  Data: <searchLink fieldCode="AU" term="%22Alvarez-Salazar+EK%22">Alvarez-Salazar EK</searchLink>; Department of Immunology, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico.; National Laboratory of Flow Cytometry, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Reyes-Barrientos+JE%22">Reyes-Barrientos JE</searchLink>; Department of Immunology, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico.; National Laboratory of Flow Cytometry, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Cortés-Hernández+A%22">Cortés-Hernández A</searchLink>; Department of Immunology, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Saint-Martin+Castellanos+A%22">Saint-Martin Castellanos A</searchLink>; Department of Immunology, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Arteaga-Cruz+S%22">Arteaga-Cruz S</searchLink>; Department of Immunology, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Cervera+A%22">Cervera A</searchLink>; Biomedical Genomics and Bioinformatics Laboratory, Instituto Nacional de Medicina Genómica, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Martínez-Iturbe+I%22">Martínez-Iturbe I</searchLink>; Department of Immunology, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Sánchez-Hernández+BE%22">Sánchez-Hernández BE</searchLink>; Department of Pathology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Gamboa-Domínguez+A%22">Gamboa-Domínguez A</searchLink>; Department of Pathology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Soldevila+G%22">Soldevila G</searchLink>; Department of Immunology, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico.; National Laboratory of Flow Cytometry, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jul 08; Vol. 17, pp. 1827886. <i>Date of Electronic Publication: </i>2026 Jul 08 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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              Text: 2026 Jul 08
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