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Effectiveness and Safety of Risankizumab in Crohn Disease After Failure of a First Line of Advanced Therapy: A Long-Term, Real-Life Study.

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Title: Effectiveness and Safety of Risankizumab in Crohn Disease After Failure of a First Line of Advanced Therapy: A Long-Term, Real-Life Study.
Authors: Tursi A; Territorial Gastroenterology Service, ASL BAT, Andria, Italy.; Department of Medical and Surgical Sciences, Catholic University, School of Medicine, Rome, Italy., Mocci G; Division of Gastroenterology, AORN 'Brotzu' Hospital, Cagliari, Italy., Scaldaferri F; Digestive Diseases Center (CEMAD), Department of Medical and Surgical Sciences, Policlinico Universitario 'A. Gemelli' Foundation, IRCCS, Rome, Italy.; Catholic University, School of Medicine, Rome, Italy., Napolitano D; Digestive Diseases Center (CEMAD), Department of Medical and Surgical Sciences, Policlinico Universitario 'A. Gemelli' Foundation, IRCCS, Rome, Italy., Gaiani F; Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy., De' Angelis G; Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy., Giuseppe Ribaldone D; Department of Medical Sciences, Division of Gastroenterology, University of Turin, IBD Unit, A.O.U. Città della Salute e della Scienza di Torino, Turin, Italy., Schillaci E; Department of Medical Sciences, Division of Gastroenterology, University of Turin, IBD Unit, A.O.U. Città della Salute e della Scienza di Torino, Turin, Italy., Savarino EV; Gastroenterology Unit, Azienda Ospedale-Università di Padova (AOUP), Padua, Italy., Barba CDE; Gastroenterology Unit, Azienda Ospedale-Università di Padova (AOUP), Padua, Italy., Bendia E; Division of Digestive Diseases, Digestive Endoscopy and Inflammatory Bowel Diseases, A.O. 'Ospedali Riuniti', Ancona, Italy., Bolognini L; Division of Digestive Diseases, Digestive Endoscopy and Inflammatory Bowel Diseases, A.O. 'Ospedali Riuniti', Ancona, Italy., Balducci D; Division of Digestive Diseases, Digestive Endoscopy and Inflammatory Bowel Diseases, A.O. 'Ospedali Riuniti', Ancona, Italy., Quatraccioni C; Division of Digestive Diseases, Digestive Endoscopy and Inflammatory Bowel Diseases, A.O. 'Ospedali Riuniti', Ancona, Italy., Martini F; Division of Digestive Diseases, Digestive Endoscopy and Inflammatory Bowel Diseases, A.O. 'Ospedali Riuniti', Ancona, Italy., Montori M; Division of Digestive Diseases, Digestive Endoscopy and Inflammatory Bowel Diseases, A.O. 'Ospedali Riuniti', Ancona, Italy., Giovanni Maconi; Gastroenterology Unit, Department of Biomedical and Clinical Sciences, 'L. Sacco' University Hospital, Milan, Italy., Cataletti G; Gastroenterology Unit, Department of Biomedical and Clinical Sciences, 'L. Sacco' University Hospital, Milan, Italy., Massari A; Gastroenterology Unit, Department of Biomedical and Clinical Sciences, 'L. Sacco' University Hospital, Milan, Italy., Del Zanna E; Gastroenterology Unit, Department of Biomedical and Clinical Sciences, 'L. Sacco' University Hospital, Milan, Italy., Costa F; IBD Unit, Department of General Surgery and Gastroenterology, Pisa University Hospital, Pisa, Italy., Ceccarelli L; IBD Unit, Department of General Surgery and Gastroenterology, Pisa University Hospital, Pisa, Italy., Gravina AG; Department of Precision Medicine, Hepatogastroenterology and Digestive Endoscopy Unit, University of Campania 'Luigi Vanvitelli', Naples, Italy., Pellegrino R; Department of Precision Medicine, Hepatogastroenterology and Digestive Endoscopy Unit, University of Campania 'Luigi Vanvitelli', Naples, Italy., Bodini G; Department of Internal Medicine and Medical Specialities, Division of Gastroenterology, IRCCS 'San Martino' Hospital, University of Genoa, Genoa, Italy., Pasta A; Department of Internal Medicine and Medical Specialities, Division of Gastroenterology, IRCCS 'San Martino' Hospital, University of Genoa, Genoa, Italy., Marzo M; Division of Gastroenterology, 'Veris-Delli Ponti' Hospital, Scorrano, Italy., Miranda A; Division of Gastroenterology, 'Monaldi' Hospital, AORN 'Dei Colli', Napoli, Italy., Cuomo A; Division of Gastroenterology, 'Umberto I' Hospital, Nocera Inferiore, Italy., Donnarumma L; Division of Gastroenterology, 'Umberto I' Hospital, Nocera Inferiore, Italy., Lombardi G; Division of Gastroenterology, AORN 'Cardarelli', Naples, Italy., Patturelli M; Division of Gastroenterology, AORN 'Cardarelli', Naples, Italy., Serio M; Division of Gastroenterology, 'San Salvatore' Hospital, Pesaro, Italy., Antonella Scarcelli; Division of Gastroenterology, 'San Salvatore' Hospital, Pesaro, Italy., Pranzo G; Ambulatory for IBD Treatment, 'Valle D'Itria' Hospital, Martina Franca, Italy., Chiara Maria Palmisano; Ambulatory for IBD Treatment, 'Valle D'Itria' Hospital, Martina Franca, Italy., Rocco Spagnuolo; Department of Health Science, University of Catanzaro, Catanzaro, Italy., Luzza F; Department of Health Science, University of Catanzaro, Catanzaro, Italy., Morano D; Department of Health Science, University of Catanzaro, Catanzaro, Italy., Vespere G; Division of Gastroenterology, 'Ospedale del Mare', ASL Na1, Naples, Italy., Sedda S; Division of Gastroenterology, 'Ospedale del Mare', ASL Na1, Naples, Italy., Luca LDE; Division of Gastroenterology, 'Ospedale del Mare', ASL Na1, Naples, Italy., Elisei W; Division of Gastroenterology, A.O. 'S. Camillo-Folanini', Rome, Italy., Monterubbianesi R; Division of Gastroenterology, A.O. 'S. Camillo-Folanini', Rome, Italy., Di Fonzo M; Division of Gastroenterology, A.O. 'S. Camillo-Folanini', Rome, Italy., Fanigliulo L; Division of Gastroenterology, 'S.S. Annunziata' Hospital, Taranto, Italy., Pica R; Division of Gastroenterology, IBD Unit, 'S. Pertini' Hospital, Rome, Italy., Cassieri C; Division of Gastroenterology, IBD Unit, 'S. Pertini' Hospital, Rome, Italy., Cocco A; Division of Gastroenterology, IBD Unit, 'S. Pertini' Hospital, Rome, Italy., Stasi E; Division of Gastroenterology, 'Vito Fazzi' Hospital, Lecce, Italy., Grossi L; Gastroenterology Unit, 'Spirito Santo' Hospital, 'G. d'Annunzio' University, Pescara, Italy., Bertani L; Division of Gastroenterology, 'Felice Lotti' Hospital, Azienda USL Toscana Nord Ovest, Pontedera, Italy., Cortellini F; Division of Gastroenterology, 'Infermi' Hospital, Rimini, Italy., Piergallini S; Division of Gastroenterology, IBD Unit, 'A. Murri' Hospital, Fermo, Italy., Scarozza P; Division of Gastroenterology, 'Ospedale dei Castelli', Ariccia, Italy., Bevevino G; Division of Gastroenterology, 'Ospedale dei Castelli', Ariccia, Italy., Zerboni G; Division of Gastroenterology, 'Ospedale dei Castelli', Ariccia, Italy., Iacopini F; Division of Gastroenterology, 'Ospedale dei Castelli', Ariccia, Italy., Rodino' S; Division of Gastroenterology, 'Ciaccio-Pugliese' Hospital, Catanzaro, Italy., Sebkova L; Division of Gastroenterology, 'Ciaccio-Pugliese' Hospital, Catanzaro, Italy., Checchin D; Division of Gastroenterology,' S Giovanni e Paolo' Hospital, Mestre - Venezia, Italy., Lamboglia F; Division of Gastroenterology,' S Giovanni e Paolo' Hospital, Mestre - Venezia, Italy., Ferrara F; Division of Gastroenterology,' S Giovanni e Paolo' Hospital, Mestre - Venezia, Italy., Della Valle N; Division of Gastroenterology, A.O. 'Ospedali Riuniti', Foggia, Italy., Colucci R; Digestive Endoscopy Unit, 'San Matteo degli Infermi' Hospital, Spoleto, Italy., Bachetti F; Digestive Endoscopy Unit, 'San Matteo degli Infermi' Hospital, Spoleto, Italy., Catarella D; Division of Gastroenterology, ARNAS 'Garibaldi', Catania, Italy., D'agostino D; Division of Gastroenterology, ARNAS 'Garibaldi', Catania, Italy., Bartolo EDI; Division of Gastroenterology, ARNAS 'Garibaldi', Catania, Italy., Luppino I; Division of Gastroenterology, 'Annunziata' Hospital, Cosenza, Italy., Erboso M; Division of Gastroenterology, 'Annunziata' Hospital, Cosenza, Italy., Rocco G; Division of Gastroenterology, 'Belcolle' Hospital, Viterbo, Italy., Sacchi C; Division of Gastroenterology, 'Belcolle' Hospital, Viterbo, Italy., Zampaletta C; Division of Gastroenterology, 'Belcolle' Hospital, Viterbo, Italy., Giacomo Forti; Division of Digestive Endoscopy, 'S. Maria Goretti' Hospital, Latina, Italy., Fiorella S; Division of Gastroenterology, 'P. Pio' Hospital, Vasto, Italy., Bassotti G; Gastroenterology & Hepatology Section, Department of Medicine & Surgery, University of Perugia, Italy., Antonelli E; Gastroenterology & Hepatology Section, Department of Medicine & Surgery, University of Perugia, Italy., Mucherino C; Division of Gastroenterology, Azienda Ospedaliera 'S. Anna e S. Sebastiano', Caserta, Italy., D'Antonio E; Division of Gastroenterology, Azienda Ospedaliera 'S. Anna e S. Sebastiano', Caserta, Italy., Montesano L; Division of Gastroenterology, Azienda Ospedaliera 'S. Anna e S. Sebastiano', Caserta, Italy., Giovannone M; Division of Gastroenterology, 'San Camillo Dè Lellis' Hospital, Rieti, Italy., Vincoli G; Division of Gastroenterology, 'San Camillo Dè Lellis' Hospital, Rieti, Italy., Gigliozzi A; Division of Gastroenterology, 'San Camillo Dè Lellis' Hospital, Rieti, Italy., D'Ascoli B; Division of Gastroenterology, 'Madonna delle Grazie' Hospital, Matera, Italy., Rizzi M; Division of Gastroenterology, 'Madonna delle Grazie' Hospital, Matera, Italy., Capone P; Division of Gastroenterology, 'T. Maresca' Hospital, Torre del Greco, Italy., Aragona G; Division of Gastroenterology, 'Guglielmo da Saliceto' Hospital, Piacenza, Italy., Perazzo P; Division of Gastroenterology, 'Guglielmo da Saliceto' Hospital, Piacenza, Italy., Allegretta L; Division of Gastroenterology, 'Santa Caterina Novella' Hospital, Galatina, Italy., Tonti P; Division of Gastroenterology, 'A. Perrino' Hospital, Brindisi, Italy., Neve V; Division of Gastroenterology, 'A. Perrino' Hospital, Brindisi, Italy., Pagnini C; Division of Gastroenterology, 'S. Giovanni - Addolorata' Hospital, Rome, Italy., Grandolfo A; Division of Gastroenterology, 'S. Paolo' Hospital, Italy., Gatti F; Division of Gastroenterology, 'S. Paolo' Hospital, Italy., Bucci A; Division of Gastroenterology, 'S. Giovanni - Addolorata' Hospital, Rome, Italy., Rizzi M; Division of Digestive Endoscopy, 'A. Perinei' Hospital, Altamura, Italy., Picchio M; Division of General Surgery, 'P. Colombo' Hospital, ASL Roma 6, Velletri, Italy., Onidi FM; Department of Medical and Surgical Sciences, Catholic University, School of Medicine, Rome, Italy., Usai Satta P; Department of Medical and Surgical Sciences, Catholic University, School of Medicine, Rome, Italy., Papa A; Digestive Diseases Center (CEMAD), Department of Medical and Surgical Sciences, Policlinico Universitario 'A. Gemelli' Foundation, IRCCS, Rome, Italy.; Catholic University, School of Medicine, Rome, Italy.
Source: American journal of therapeutics [Am J Ther] 2026 Jul 23. Date of Electronic Publication: 2026 Jul 23.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9441347 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-3686 (Electronic) Linking ISSN: 10752765 NLM ISO Abbreviation: Am J Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42490306
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: Effectiveness and Safety of Risankizumab in Crohn Disease After Failure of a First Line of Advanced Therapy: A Long-Term, Real-Life Study.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Tursi+A%22">Tursi A</searchLink>; Territorial Gastroenterology Service, ASL BAT, Andria, Italy.; Department of Medical and Surgical Sciences, Catholic University, School of Medicine, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Mocci+G%22">Mocci G</searchLink>; Division of Gastroenterology, AORN 'Brotzu' Hospital, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Scaldaferri+F%22">Scaldaferri F</searchLink>; Digestive Diseases Center (CEMAD), Department of Medical and Surgical Sciences, Policlinico Universitario 'A. Gemelli' Foundation, IRCCS, Rome, Italy.; Catholic University, School of Medicine, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Napolitano+D%22">Napolitano D</searchLink>; Digestive Diseases Center (CEMAD), Department of Medical and Surgical Sciences, Policlinico Universitario 'A. Gemelli' Foundation, IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Gaiani+F%22">Gaiani F</searchLink>; Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22De'+Angelis+G%22">De' Angelis G</searchLink>; Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Giuseppe+Ribaldone+D%22">Giuseppe Ribaldone D</searchLink>; Department of Medical Sciences, Division of Gastroenterology, University of Turin, IBD Unit, A.O.U. Città della Salute e della Scienza di Torino, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Schillaci+E%22">Schillaci E</searchLink>; Department of Medical Sciences, Division of Gastroenterology, University of Turin, IBD Unit, A.O.U. Città della Salute e della Scienza di Torino, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Savarino+EV%22">Savarino EV</searchLink>; Gastroenterology Unit, Azienda Ospedale-Università di Padova (AOUP), Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Barba+CDE%22">Barba CDE</searchLink>; Gastroenterology Unit, Azienda Ospedale-Università di Padova (AOUP), Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Bendia+E%22">Bendia E</searchLink>; Division of Digestive Diseases, Digestive Endoscopy and Inflammatory Bowel Diseases, A.O. 'Ospedali Riuniti', Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Bolognini+L%22">Bolognini L</searchLink>; Division of Digestive Diseases, Digestive Endoscopy and Inflammatory Bowel Diseases, A.O. 'Ospedali Riuniti', Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Balducci+D%22">Balducci D</searchLink>; Division of Digestive Diseases, Digestive Endoscopy and Inflammatory Bowel Diseases, A.O. 'Ospedali Riuniti', Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Quatraccioni+C%22">Quatraccioni C</searchLink>; Division of Digestive Diseases, Digestive Endoscopy and Inflammatory Bowel Diseases, A.O. 'Ospedali Riuniti', Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Martini+F%22">Martini F</searchLink>; Division of Digestive Diseases, Digestive Endoscopy and Inflammatory Bowel Diseases, A.O. 'Ospedali Riuniti', Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Montori+M%22">Montori M</searchLink>; Division of Digestive Diseases, Digestive Endoscopy and Inflammatory Bowel Diseases, A.O. 'Ospedali Riuniti', Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Giovanni+Maconi%22">Giovanni Maconi</searchLink>; Gastroenterology Unit, Department of Biomedical and Clinical Sciences, 'L. Sacco' University Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cataletti+G%22">Cataletti G</searchLink>; Gastroenterology Unit, Department of Biomedical and Clinical Sciences, 'L. Sacco' University Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Massari+A%22">Massari A</searchLink>; Gastroenterology Unit, Department of Biomedical and Clinical Sciences, 'L. Sacco' University Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Del+Zanna+E%22">Del Zanna E</searchLink>; Gastroenterology Unit, Department of Biomedical and Clinical Sciences, 'L. Sacco' University Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Costa+F%22">Costa F</searchLink>; IBD Unit, Department of General Surgery and Gastroenterology, Pisa University Hospital, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Ceccarelli+L%22">Ceccarelli L</searchLink>; IBD Unit, Department of General Surgery and Gastroenterology, Pisa University Hospital, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Gravina+AG%22">Gravina AG</searchLink>; Department of Precision Medicine, Hepatogastroenterology and Digestive Endoscopy Unit, University of Campania 'Luigi Vanvitelli', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Pellegrino+R%22">Pellegrino R</searchLink>; Department of Precision Medicine, Hepatogastroenterology and Digestive Endoscopy Unit, University of Campania 'Luigi Vanvitelli', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Bodini+G%22">Bodini G</searchLink>; Department of Internal Medicine and Medical Specialities, Division of Gastroenterology, IRCCS 'San Martino' Hospital, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Pasta+A%22">Pasta A</searchLink>; Department of Internal Medicine and Medical Specialities, Division of Gastroenterology, IRCCS 'San Martino' Hospital, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Marzo+M%22">Marzo M</searchLink>; Division of Gastroenterology, 'Veris-Delli Ponti' Hospital, Scorrano, Italy.<br /><searchLink fieldCode="AU" term="%22Miranda+A%22">Miranda A</searchLink>; Division of Gastroenterology, 'Monaldi' Hospital, AORN 'Dei Colli', Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Cuomo+A%22">Cuomo A</searchLink>; Division of Gastroenterology, 'Umberto I' Hospital, Nocera Inferiore, Italy.<br /><searchLink fieldCode="AU" term="%22Donnarumma+L%22">Donnarumma L</searchLink>; Division of Gastroenterology, 'Umberto I' Hospital, Nocera Inferiore, Italy.<br /><searchLink fieldCode="AU" term="%22Lombardi+G%22">Lombardi G</searchLink>; Division of Gastroenterology, AORN 'Cardarelli', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Patturelli+M%22">Patturelli M</searchLink>; Division of Gastroenterology, AORN 'Cardarelli', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Serio+M%22">Serio M</searchLink>; Division of Gastroenterology, 'San Salvatore' Hospital, Pesaro, Italy.<br /><searchLink fieldCode="AU" term="%22Antonella+Scarcelli%22">Antonella Scarcelli</searchLink>; Division of Gastroenterology, 'San Salvatore' Hospital, Pesaro, Italy.<br /><searchLink fieldCode="AU" term="%22Pranzo+G%22">Pranzo G</searchLink>; Ambulatory for IBD Treatment, 'Valle D'Itria' Hospital, Martina Franca, Italy.<br /><searchLink fieldCode="AU" term="%22Chiara+Maria+Palmisano%22">Chiara Maria Palmisano</searchLink>; Ambulatory for IBD Treatment, 'Valle D'Itria' Hospital, Martina Franca, Italy.<br /><searchLink fieldCode="AU" term="%22Rocco+Spagnuolo%22">Rocco Spagnuolo</searchLink>; Department of Health Science, University of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Luzza+F%22">Luzza F</searchLink>; Department of Health Science, University of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Morano+D%22">Morano D</searchLink>; Department of Health Science, University of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Vespere+G%22">Vespere G</searchLink>; Division of Gastroenterology, 'Ospedale del Mare', ASL Na1, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Sedda+S%22">Sedda S</searchLink>; Division of Gastroenterology, 'Ospedale del Mare', ASL Na1, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Luca+LDE%22">Luca LDE</searchLink>; Division of Gastroenterology, 'Ospedale del Mare', ASL Na1, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Elisei+W%22">Elisei W</searchLink>; Division of Gastroenterology, A.O. 'S. Camillo-Folanini', Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Monterubbianesi+R%22">Monterubbianesi R</searchLink>; Division of Gastroenterology, A.O. 'S. Camillo-Folanini', Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Fonzo+M%22">Di Fonzo M</searchLink>; Division of Gastroenterology, A.O. 'S. Camillo-Folanini', Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Fanigliulo+L%22">Fanigliulo L</searchLink>; Division of Gastroenterology, 'S.S. Annunziata' Hospital, Taranto, Italy.<br /><searchLink fieldCode="AU" term="%22Pica+R%22">Pica R</searchLink>; Division of Gastroenterology, IBD Unit, 'S. Pertini' Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Cassieri+C%22">Cassieri C</searchLink>; Division of Gastroenterology, IBD Unit, 'S. Pertini' Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Cocco+A%22">Cocco A</searchLink>; Division of Gastroenterology, IBD Unit, 'S. Pertini' Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Stasi+E%22">Stasi E</searchLink>; Division of Gastroenterology, 'Vito Fazzi' Hospital, Lecce, Italy.<br /><searchLink fieldCode="AU" term="%22Grossi+L%22">Grossi L</searchLink>; Gastroenterology Unit, 'Spirito Santo' Hospital, 'G. d'Annunzio' University, Pescara, Italy.<br /><searchLink fieldCode="AU" term="%22Bertani+L%22">Bertani L</searchLink>; Division of Gastroenterology, 'Felice Lotti' Hospital, Azienda USL Toscana Nord Ovest, Pontedera, Italy.<br /><searchLink fieldCode="AU" term="%22Cortellini+F%22">Cortellini F</searchLink>; Division of Gastroenterology, 'Infermi' Hospital, Rimini, Italy.<br /><searchLink fieldCode="AU" term="%22Piergallini+S%22">Piergallini S</searchLink>; Division of Gastroenterology, IBD Unit, 'A. Murri' Hospital, Fermo, Italy.<br /><searchLink fieldCode="AU" term="%22Scarozza+P%22">Scarozza P</searchLink>; Division of Gastroenterology, 'Ospedale dei Castelli', Ariccia, Italy.<br /><searchLink fieldCode="AU" term="%22Bevevino+G%22">Bevevino G</searchLink>; Division of Gastroenterology, 'Ospedale dei Castelli', Ariccia, Italy.<br /><searchLink fieldCode="AU" term="%22Zerboni+G%22">Zerboni G</searchLink>; Division of Gastroenterology, 'Ospedale dei Castelli', Ariccia, Italy.<br /><searchLink fieldCode="AU" term="%22Iacopini+F%22">Iacopini F</searchLink>; Division of Gastroenterology, 'Ospedale dei Castelli', Ariccia, Italy.<br /><searchLink fieldCode="AU" term="%22Rodino'+S%22">Rodino' S</searchLink>; Division of Gastroenterology, 'Ciaccio-Pugliese' Hospital, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Sebkova+L%22">Sebkova L</searchLink>; Division of Gastroenterology, 'Ciaccio-Pugliese' Hospital, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Checchin+D%22">Checchin D</searchLink>; Division of Gastroenterology,' S Giovanni e Paolo' Hospital, Mestre - Venezia, Italy.<br /><searchLink fieldCode="AU" term="%22Lamboglia+F%22">Lamboglia F</searchLink>; Division of Gastroenterology,' S Giovanni e Paolo' Hospital, Mestre - Venezia, Italy.<br /><searchLink fieldCode="AU" term="%22Ferrara+F%22">Ferrara F</searchLink>; Division of Gastroenterology,' S Giovanni e Paolo' Hospital, Mestre - Venezia, Italy.<br /><searchLink fieldCode="AU" term="%22Della+Valle+N%22">Della Valle N</searchLink>; Division of Gastroenterology, A.O. 'Ospedali Riuniti', Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Colucci+R%22">Colucci R</searchLink>; Digestive Endoscopy Unit, 'San Matteo degli Infermi' Hospital, Spoleto, Italy.<br /><searchLink fieldCode="AU" term="%22Bachetti+F%22">Bachetti F</searchLink>; Digestive Endoscopy Unit, 'San Matteo degli Infermi' Hospital, Spoleto, Italy.<br /><searchLink fieldCode="AU" term="%22Catarella+D%22">Catarella D</searchLink>; Division of Gastroenterology, ARNAS 'Garibaldi', Catania, Italy.<br /><searchLink fieldCode="AU" term="%22D'agostino+D%22">D'agostino D</searchLink>; Division of Gastroenterology, ARNAS 'Garibaldi', Catania, Italy.<br /><searchLink fieldCode="AU" term="%22Bartolo+EDI%22">Bartolo EDI</searchLink>; Division of Gastroenterology, ARNAS 'Garibaldi', Catania, Italy.<br /><searchLink fieldCode="AU" term="%22Luppino+I%22">Luppino I</searchLink>; Division of Gastroenterology, 'Annunziata' Hospital, Cosenza, Italy.<br /><searchLink fieldCode="AU" term="%22Erboso+M%22">Erboso M</searchLink>; Division of Gastroenterology, 'Annunziata' Hospital, Cosenza, Italy.<br /><searchLink fieldCode="AU" term="%22Rocco+G%22">Rocco G</searchLink>; Division of Gastroenterology, 'Belcolle' Hospital, Viterbo, Italy.<br /><searchLink fieldCode="AU" term="%22Sacchi+C%22">Sacchi C</searchLink>; Division of Gastroenterology, 'Belcolle' Hospital, Viterbo, Italy.<br /><searchLink fieldCode="AU" term="%22Zampaletta+C%22">Zampaletta C</searchLink>; Division of Gastroenterology, 'Belcolle' Hospital, Viterbo, Italy.<br /><searchLink fieldCode="AU" term="%22Giacomo+Forti%22">Giacomo Forti</searchLink>; Division of Digestive Endoscopy, 'S. Maria Goretti' Hospital, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Fiorella+S%22">Fiorella S</searchLink>; Division of Gastroenterology, 'P. Pio' Hospital, Vasto, Italy.<br /><searchLink fieldCode="AU" term="%22Bassotti+G%22">Bassotti G</searchLink>; Gastroenterology & Hepatology Section, Department of Medicine & Surgery, University of Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Antonelli+E%22">Antonelli E</searchLink>; Gastroenterology & Hepatology Section, Department of Medicine & Surgery, University of Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Mucherino+C%22">Mucherino C</searchLink>; Division of Gastroenterology, Azienda Ospedaliera 'S. Anna e S. Sebastiano', Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22D'Antonio+E%22">D'Antonio E</searchLink>; Division of Gastroenterology, Azienda Ospedaliera 'S. Anna e S. Sebastiano', Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Montesano+L%22">Montesano L</searchLink>; Division of Gastroenterology, Azienda Ospedaliera 'S. Anna e S. Sebastiano', Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Giovannone+M%22">Giovannone M</searchLink>; Division of Gastroenterology, 'San Camillo Dè Lellis' Hospital, Rieti, Italy.<br /><searchLink fieldCode="AU" term="%22Vincoli+G%22">Vincoli G</searchLink>; Division of Gastroenterology, 'San Camillo Dè Lellis' Hospital, Rieti, Italy.<br /><searchLink fieldCode="AU" term="%22Gigliozzi+A%22">Gigliozzi A</searchLink>; Division of Gastroenterology, 'San Camillo Dè Lellis' Hospital, Rieti, Italy.<br /><searchLink fieldCode="AU" term="%22D'Ascoli+B%22">D'Ascoli B</searchLink>; Division of Gastroenterology, 'Madonna delle Grazie' Hospital, Matera, Italy.<br /><searchLink fieldCode="AU" term="%22Rizzi+M%22">Rizzi M</searchLink>; Division of Gastroenterology, 'Madonna delle Grazie' Hospital, Matera, Italy.<br /><searchLink fieldCode="AU" term="%22Capone+P%22">Capone P</searchLink>; Division of Gastroenterology, 'T. Maresca' Hospital, Torre del Greco, Italy.<br /><searchLink fieldCode="AU" term="%22Aragona+G%22">Aragona G</searchLink>; Division of Gastroenterology, 'Guglielmo da Saliceto' Hospital, Piacenza, Italy.<br /><searchLink fieldCode="AU" term="%22Perazzo+P%22">Perazzo P</searchLink>; Division of Gastroenterology, 'Guglielmo da Saliceto' Hospital, Piacenza, Italy.<br /><searchLink fieldCode="AU" term="%22Allegretta+L%22">Allegretta L</searchLink>; Division of Gastroenterology, 'Santa Caterina Novella' Hospital, Galatina, Italy.<br /><searchLink fieldCode="AU" term="%22Tonti+P%22">Tonti P</searchLink>; Division of Gastroenterology, 'A. Perrino' Hospital, Brindisi, Italy.<br /><searchLink fieldCode="AU" term="%22Neve+V%22">Neve V</searchLink>; Division of Gastroenterology, 'A. Perrino' Hospital, Brindisi, Italy.<br /><searchLink fieldCode="AU" term="%22Pagnini+C%22">Pagnini C</searchLink>; Division of Gastroenterology, 'S. Giovanni - Addolorata' Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Grandolfo+A%22">Grandolfo A</searchLink>; Division of Gastroenterology, 'S. Paolo' Hospital, Italy.<br /><searchLink fieldCode="AU" term="%22Gatti+F%22">Gatti F</searchLink>; Division of Gastroenterology, 'S. Paolo' Hospital, Italy.<br /><searchLink fieldCode="AU" term="%22Bucci+A%22">Bucci A</searchLink>; Division of Gastroenterology, 'S. Giovanni - Addolorata' Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Rizzi+M%22">Rizzi M</searchLink>; Division of Digestive Endoscopy, 'A. Perinei' Hospital, Altamura, Italy.<br /><searchLink fieldCode="AU" term="%22Picchio+M%22">Picchio M</searchLink>; Division of General Surgery, 'P. Colombo' Hospital, ASL Roma 6, Velletri, Italy.<br /><searchLink fieldCode="AU" term="%22Onidi+FM%22">Onidi FM</searchLink>; Department of Medical and Surgical Sciences, Catholic University, School of Medicine, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Usai+Satta+P%22">Usai Satta P</searchLink>; Department of Medical and Surgical Sciences, Catholic University, School of Medicine, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Papa+A%22">Papa A</searchLink>; Digestive Diseases Center (CEMAD), Department of Medical and Surgical Sciences, Policlinico Universitario 'A. Gemelli' Foundation, IRCCS, Rome, Italy.; Catholic University, School of Medicine, Rome, Italy.
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  Data: <searchLink fieldCode="JN" term="%229441347%22">American journal of therapeutics</searchLink> [Am J Ther] 2026 Jul 23. <i>Date of Electronic Publication: </i>2026 Jul 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott+Williams+%26+Wilkins%22">Lippincott Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9441347 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1536-3686 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210752765%22">10752765 </searchLink><i>NLM ISO Abbreviation: </i>Am J Ther <i>Subsets: </i>MEDLINE
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      – TitleFull: Effectiveness and Safety of Risankizumab in Crohn Disease After Failure of a First Line of Advanced Therapy: A Long-Term, Real-Life Study.
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